DK459088A - Plasminogenaktivatorer - Google Patents

Plasminogenaktivatorer

Info

Publication number
DK459088A
DK459088A DK459088A DK459088A DK459088A DK 459088 A DK459088 A DK 459088A DK 459088 A DK459088 A DK 459088A DK 459088 A DK459088 A DK 459088A DK 459088 A DK459088 A DK 459088A
Authority
DK
Denmark
Prior art keywords
plasminogen activators
plasminogen
activators
Prior art date
Application number
DK459088A
Other languages
English (en)
Other versions
DK459088D0 (da
Inventor
Alex Joseph Bollen
Dirk Gheysen
Paul Jacobs
Laurent Pierard
Desire J Collen
Original Assignee
Smith Kline Rit
Leuven Res & Dev Vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit, Leuven Res & Dev Vzw filed Critical Smith Kline Rit
Publication of DK459088A publication Critical patent/DK459088A/da
Publication of DK459088D0 publication Critical patent/DK459088D0/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK459088A 1986-12-16 1988-08-16 Plasminogenaktivatorer DK459088D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94212786A 1986-12-16 1986-12-16
PCT/BE1987/000018 WO1988004690A1 (en) 1986-12-16 1987-12-11 New plasminogen activators

Publications (2)

Publication Number Publication Date
DK459088A true DK459088A (da) 1988-08-16
DK459088D0 DK459088D0 (da) 1988-08-16

Family

ID=25477615

Family Applications (1)

Application Number Title Priority Date Filing Date
DK459088A DK459088D0 (da) 1986-12-16 1988-08-16 Plasminogenaktivatorer

Country Status (8)

Country Link
EP (1) EP0275856A1 (da)
JP (1) JPH02501106A (da)
AU (1) AU1103588A (da)
DK (1) DK459088D0 (da)
IE (1) IE873398L (da)
PT (1) PT86383B (da)
WO (1) WO1988004690A1 (da)
ZA (1) ZA879286B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204255A (en) * 1986-01-31 1993-04-20 Sagami Chemical Research Center Hybrid tissue plasminogen activator/urokinase polypeptides
AU3410289A (en) * 1988-04-22 1989-11-24 Collaborative Research Inc. Plasminogen activators with increased fibrin selectivity
EP0966197A1 (en) * 1996-08-14 1999-12-29 Myung Hee Chun Plasmin-depletion therapy
IN190822B (da) * 1998-12-24 2003-08-23 Council Scient Ind Res
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
FI88932C (fi) 1982-04-15 1993-07-26 Genentech Inc Framstaellning av funktionellt maenskligt urokinasprotein
IL68561A (en) 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
GR81701B (da) 1983-01-18 1984-12-12 Lilly Co Eli
AU572108B2 (en) 1983-01-19 1988-05-05 Genentech Inc. Human tpa production using vectors coding for dhfr protein
GR80966B (en) 1983-11-21 1985-03-15 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
EP0154272B1 (en) 1984-02-27 1992-01-08 Green Cross Corporation Production of human urokinase
US4758512A (en) 1984-03-06 1988-07-19 President And Fellows Of Harvard College Hosts and methods for producing recombinant products in high yields
DE3584341D1 (de) 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
DE3781420T2 (de) * 1986-01-31 1993-02-25 Central Glass Co Ltd Hybrides plasminogenaktivatoraehnliches polypeptid.

Also Published As

Publication number Publication date
PT86383B (pt) 1990-11-20
EP0275856A1 (en) 1988-07-27
PT86383A (en) 1988-01-01
ZA879286B (en) 1988-10-26
DK459088D0 (da) 1988-08-16
IE873398L (en) 1988-06-16
AU1103588A (en) 1988-07-15
JPH02501106A (ja) 1990-04-19
WO1988004690A1 (en) 1988-06-30

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment