DK463885A - Indomethacin- eller oxicam-baseret anti-inflammatorisk praeparat - Google Patents

Indomethacin- eller oxicam-baseret anti-inflammatorisk praeparat Download PDF

Info

Publication number: DK463885A
Authority: DK; Denmark
Prior art keywords: guanidino; imidazolyl; oxicam; indomethacin; thiazole
Prior art date: 1984-10-11

Application number

DK463885A

Other languages

English (en)

Other versions

DK165964C (da

DK463885D0 (da

DK165964B (da

Inventor

John Lawrence Lamattina

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-11

Filing date

1985-10-10

Publication date

1986-04-12

1985-10-10 Application filed by Pfizer filed Critical Pfizer

1985-10-10 Publication of DK463885D0 publication Critical patent/DK463885D0/da

1986-04-12 Publication of DK463885A publication Critical patent/DK463885A/da

1993-02-22 Publication of DK165964B publication Critical patent/DK165964B/da

1993-07-26 Application granted granted Critical

1993-07-26 Publication of DK165964C publication Critical patent/DK165964C/da

Links

CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 title abstract 4
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
229960000905 indomethacin Drugs 0.000 title abstract 2
FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 3
RROBYWWPVULLSU-UHFFFAOYSA-N 2-[4-(1h-imidazol-5-yl)-1,3-thiazol-2-yl]guanidine Chemical compound S1C(NC(=N)N)=NC(C=2N=CNC=2)=C1 RROBYWWPVULLSU-UHFFFAOYSA-N 0.000 abstract 1
206010061218 Inflammation Diseases 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Radiation-Therapy Devices (AREA)
Electron Beam Exposure (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)

DK463885A 1984-10-11 1985-10-10 Forbedret indomethancin- eller oxicam-baseret anti-inflammatorisk praeparat DK165964C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US65975284A	1984-10-11	1984-10-11
US65975284		1984-10-11
US06/765,415 US4636498A (en)	1984-10-11	1985-08-15	Formulation of antiinflammatory drugs
US76541585		1985-08-15

Publications (4)

Publication Number	Publication Date
DK463885D0 DK463885D0 (da)	1985-10-10
DK463885A true DK463885A (da)	1986-04-12
DK165964B DK165964B (da)	1993-02-22
DK165964C DK165964C (da)	1993-07-26

Family

ID=27097890

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK463885A DK165964C (da)	1984-10-11	1985-10-10	Forbedret indomethancin- eller oxicam-baseret anti-inflammatorisk praeparat

Country Status (16)

Country	Link
US (1)	US4636498A (da)
EP (1)	EP0178121B1 (da)
CN (1)	CN1011196B (da)
AT (1)	ATE53492T1 (da)
AU (1)	AU558668B2 (da)
CA (1)	CA1251138A (da)
DE (1)	DE3578125D1 (da)
DK (1)	DK165964C (da)
EG (1)	EG17529A (da)
FI (1)	FI853948L (da)
GR (1)	GR852459B (da)
IE (1)	IE58740B1 (da)
IL (1)	IL76647A0 (da)
NZ (1)	NZ213756A (da)
PH (1)	PH21400A (da)
PT (1)	PT81280B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1196307B (it) *	1984-10-22	1988-11-16	Chiesi Farma Spa	Formulazioni farmaceutiche acquose di piroxicam monoidrato
US5260333A (en) *	1986-08-08	1993-11-09	Bristol Myers Squibb Company	Effect of a combination of a terbutaline, diphenhydramine and ranitidine composition on gastrointestinal injury produced by nonsteroidal anti-inflammatory compositions
GB8625325D0 (en) *	1986-10-22	1986-11-26	Glaxo Group Ltd	Chemical compounds
NZ230701A (en) *	1988-09-20	1992-01-29	Glaxo Group Ltd	Pharmaceutical compositions comprising ranitidine, alginic acid and a carbonate or bicarbonate
EP0703782A1 (en) *	1993-06-15	1996-04-03	Pfizer Inc.	H2-antagonists as immune stimulants in bacterial infections of cattle or swine
US20060281775A1 (en) *	2005-06-14	2006-12-14	Applied Pharmacy Services, Inc.	Two-component pharmaceutical composition for the treatment of pain

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL6715112A (da) *	1966-11-21	1968-05-22
US4230717A (en) *	1978-12-29	1980-10-28	Lovelace Alan M Administrator	Indomethacin-antihistamine combination for gastric ulceration control
GB2105193B (en) *	1981-09-04	1984-09-12	Glaxo Group Ltd	Pharmaceutical compositions containing non-steroidal anti-inflammatory agents
BE894286A (fr) *	1981-09-04	1983-03-02	Glaxo Group Ltd	Composition pharmaceutique contenant un medicament anti-inflammatoire systemique non steroidique et du 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)-propyl)amino -1h-1,2,4-triazole-3-methanol ou un sel de ce compose
US4435396A (en) *	1982-05-10	1984-03-06	Pfizer Inc.	Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor
US4447443A (en) *	1982-11-15	1984-05-08	Merck & Co., Inc.	Anti-inflammatory/analgesic combination of α-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID)

1985
- 1985-08-15 US US06/765,415 patent/US4636498A/en not_active Expired - Fee Related
- 1985-10-02 EP EP85307055A patent/EP0178121B1/en not_active Expired - Lifetime
- 1985-10-02 DE DE8585307055T patent/DE3578125D1/de not_active Expired - Lifetime
- 1985-10-02 AT AT85307055T patent/ATE53492T1/de active
- 1985-10-09 PT PT81280A patent/PT81280B/pt unknown
- 1985-10-09 GR GR852459A patent/GR852459B/el unknown
- 1985-10-09 CA CA000492568A patent/CA1251138A/en not_active Expired
- 1985-10-09 NZ NZ213756A patent/NZ213756A/xx unknown
- 1985-10-10 CN CN85107521A patent/CN1011196B/zh not_active Expired
- 1985-10-10 FI FI853948A patent/FI853948L/fi not_active Application Discontinuation
- 1985-10-10 IL IL76647A patent/IL76647A0/xx not_active IP Right Cessation
- 1985-10-10 EG EG648/85A patent/EG17529A/xx active
- 1985-10-10 PH PH32913A patent/PH21400A/en unknown
- 1985-10-10 IE IE249485A patent/IE58740B1/en not_active IP Right Cessation
- 1985-10-10 DK DK463885A patent/DK165964C/da not_active IP Right Cessation
- 1985-10-10 AU AU48485/85A patent/AU558668B2/en not_active Ceased

Also Published As

Publication number	Publication date
PT81280B (pt)	1988-02-17
FI853948A0 (fi)	1985-10-10
CN1011196B (zh)	1991-01-16
IL76647A0 (en)	1986-02-28
DK165964C (da)	1993-07-26
US4636498A (en)	1987-01-13
AU558668B2 (en)	1987-02-05
GR852459B (da)	1986-02-11
CN85107521A (zh)	1986-08-06
PH21400A (en)	1987-10-15
CA1251138A (en)	1989-03-14
EP0178121B1 (en)	1990-06-13
IE852494L (en)	1987-02-15
DK463885D0 (da)	1985-10-10
PT81280A (en)	1985-11-01
FI853948A7 (fi)	1986-04-12
FI853948L (fi)	1986-04-12
EG17529A (en)	1993-08-30
DK165964B (da)	1993-02-22
AU4848585A (en)	1986-05-08
DE3578125D1 (de)	1990-07-19
IE58740B1 (en)	1993-11-03
EP0178121A3 (en)	1988-10-05
NZ213756A (en)	1988-11-29
ATE53492T1 (de)	1990-06-15
EP0178121A2 (en)	1986-04-16

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Legal Events

Date	Code	Title	Description
1995-06-26	PBP	Patent lapsed