DK465377A - Fremgangsmaade til fremstilling af cis-isomeren af n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyliden) thioxanthen-2-sulfonamid - Google Patents

Fremgangsmaade til fremstilling af cis-isomeren af n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyliden) thioxanthen-2-sulfonamid

Info

Publication number: DK465377A
Authority: DK; Denmark
Prior art keywords: thioxanthene; sulphonamide; propylidene; piperazinyl; dimethyl
Prior art date: 1976-10-20

Application number

DK465377A

Other languages

English (en)

Other versions

DK159314B (da

DK159314C (da

Inventor

D E Kuhla

H A Watson

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-10-20

Filing date

1977-10-19

Publication date

1978-04-21

1977-10-19 Application filed by Pfizer filed Critical Pfizer

1978-04-21 Publication of DK465377A publication Critical patent/DK465377A/da

1990-10-01 Publication of DK159314B publication Critical patent/DK159314B/da

1991-02-25 Application granted granted Critical

1991-02-25 Publication of DK159314C publication Critical patent/DK159314C/da

Links

-1 3- (4-METHYL-1-PIPERAZINYL) PROPYLIDENE Chemical class 0.000 title 1
IRDOTPJGMVWQRT-UHFFFAOYSA-N 9h-thioxanthene-2-sulfonamide Chemical compound C1=CC=C2CC3=CC(S(=O)(=O)N)=CC=C3SC2=C1 IRDOTPJGMVWQRT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/20—Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK465377A 1976-10-20 1977-10-19 Fremgangsmaade til fremstilling af cis-isomeren af n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyliden)thioxanthen-2-sulfonamid DK159314C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73408176		1976-10-20
US05/734,081 US4107430A (en)	1976-10-20	1976-10-20	Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer

Publications (3)

Publication Number	Publication Date
DK465377A true DK465377A (da)	1978-04-21
DK159314B DK159314B (da)	1990-10-01
DK159314C DK159314C (da)	1991-02-25

Family

ID=24950235

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK465377A DK159314C (da)	1976-10-20	1977-10-19	Fremgangsmaade til fremstilling af cis-isomeren af n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyliden)thioxanthen-2-sulfonamid

Country Status (37)

Country	Link
US (1)	US4107430A (da)
JP (1)	JPS5353674A (da)
AR (1)	AR213867A1 (da)
AT (1)	AT360025B (da)
AU (1)	AU499048B2 (da)
BE (1)	BE859907A (da)
BG (1)	BG32852A3 (da)
CA (1)	CA1085399A (da)
CH (1)	CH625519A5 (da)
CS (1)	CS192494B2 (da)
DD (1)	DD133438A5 (da)
DE (1)	DE2746762C3 (da)
DK (1)	DK159314C (da)
ES (1)	ES463343A1 (da)
FI (1)	FI63939C (da)
FR (1)	FR2368485A1 (da)
GB (1)	GB1542004A (da)
GR (1)	GR69786B (da)
HK (1)	HK31081A (da)
HU (1)	HU173644B (da)
IE (1)	IE45715B1 (da)
IL (1)	IL53056A (da)
IN (1)	IN146954B (da)
LU (1)	LU78336A1 (da)
MX (1)	MX4843E (da)
MY (1)	MY8100275A (da)
NL (1)	NL172062C (da)
NO (1)	NO148713C (da)
NZ (1)	NZ185461A (da)
PH (1)	PH13941A (da)
PL (1)	PL106962B1 (da)
PT (1)	PT67171B (da)
RO (1)	RO74135A (da)
SE (1)	SE437828B (da)
SU (1)	SU831078A3 (da)
YU (1)	YU40978B (da)
ZA (1)	ZA776216B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2998303B1 (en)	2014-09-17	2018-06-13	B & G Partners, LLC	Phenothiazine derivatives and methods for treating tumors
CN107987053B (zh) *	2017-12-08	2023-04-14	植恩生物技术股份有限公司	一种高纯度z型盐酸氟哌噻吨的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3115502A (en) *	1959-06-19	1963-12-24	Hoffmann La Roche	Method of isomerizing basically substituted stereoisomeric thioxanthenes
NL103196C (da) *	1959-06-19
US3310553A (en) *	1962-09-25	1967-03-21	Pfizer & Co C	Alkylated thioxathenesulfonamides
US3514449A (en) *	1967-01-16	1970-05-26	Pfizer & Co C	Process for separating the cis isomer from a mixture of cis and trans n-(3 - (2 - chlorodibenz(b,e)oxepin - 11(6h)-ylidene)-propyl)piperazine
US3681346A (en) *	1969-06-20	1972-08-01	Kefalas As	{60 -isomer of the decanoic acid ester of 10-{8 3,-(4-hydroxyethyl-1-piperazinyl)propylidene{9 -2-trifluoro-methyl thiaxanthene, acid addition salts thereof, method of use and compositions
SU540867A1 (ru) *	1975-06-16	1976-12-30	Предприятие П/Я М-5927	Способ получени цис- -диметил9-/3-(4-метил-1-пиперазинил)-пропилиден/-тиоксантен-2-сульфонамида

1976
- 1976-10-20 US US05/734,081 patent/US4107430A/en not_active Expired - Lifetime
1977
- 1977-04-19 AU AU29690/77A patent/AU499048B2/en not_active Expired
- 1977-09-26 SE SE7710759A patent/SE437828B/sv not_active IP Right Cessation
- 1977-10-03 IN IN286/DEL/77A patent/IN146954B/en unknown
- 1977-10-04 GR GR54504A patent/GR69786B/el unknown
- 1977-10-05 IL IL53056A patent/IL53056A/xx unknown
- 1977-10-07 PH PH20316A patent/PH13941A/en unknown
- 1977-10-10 YU YU2438/77A patent/YU40978B/xx unknown
- 1977-10-13 AT AT732077A patent/AT360025B/de not_active IP Right Cessation
- 1977-10-14 MX MX776482U patent/MX4843E/es unknown
- 1977-10-17 FI FI773073A patent/FI63939C/fi not_active IP Right Cessation
- 1977-10-17 RO RO7791862A patent/RO74135A/ro unknown
- 1977-10-17 JP JP12437277A patent/JPS5353674A/ja active Granted
- 1977-10-18 BG BG037599A patent/BG32852A3/xx unknown
- 1977-10-18 LU LU78336A patent/LU78336A1/xx unknown
- 1977-10-18 PL PL1977201585A patent/PL106962B1/pl unknown
- 1977-10-18 DE DE2746762A patent/DE2746762C3/de not_active Expired
- 1977-10-18 CH CH1271377A patent/CH625519A5/fr not_active IP Right Cessation
- 1977-10-18 NZ NZ185461A patent/NZ185461A/xx unknown
- 1977-10-18 CA CA288,928A patent/CA1085399A/en not_active Expired
- 1977-10-18 PT PT67171A patent/PT67171B/pt unknown
- 1977-10-19 DK DK465377A patent/DK159314C/da not_active IP Right Cessation
- 1977-10-19 HU HU77PI595A patent/HU173644B/hu unknown
- 1977-10-19 GB GB7743542A patent/GB1542004A/en not_active Expired
- 1977-10-19 IE IE2134/77A patent/IE45715B1/en not_active IP Right Cessation
- 1977-10-19 SU SU772531950A patent/SU831078A3/ru active
- 1977-10-19 ZA ZA00776216A patent/ZA776216B/xx unknown
- 1977-10-19 FR FR7731487A patent/FR2368485A1/fr active Granted
- 1977-10-19 BE BE181889A patent/BE859907A/xx not_active IP Right Cessation
- 1977-10-19 CS CS776800A patent/CS192494B2/cs unknown
- 1977-10-19 NO NO773588A patent/NO148713C/no unknown
- 1977-10-19 NL NLAANVRAGE7711471,A patent/NL172062C/xx not_active IP Right Cessation
- 1977-10-19 ES ES463343A patent/ES463343A1/es not_active Expired
- 1977-10-20 AR AR269655A patent/AR213867A1/es active
- 1977-10-20 DD DD77201628A patent/DD133438A5/xx unknown
1981
- 1981-07-02 HK HK310/81A patent/HK31081A/xx not_active IP Right Cessation
- 1981-12-30 MY MY275/81A patent/MY8100275A/xx unknown

Also Published As

Publication number	Publication date
CA1085399A (en)	1980-09-09
ZA776216B (en)	1978-06-28
FI63939C (fi)	1983-09-12
DD133438A5 (de)	1979-01-03
CH625519A5 (da)	1981-09-30
PT67171B (pt)	1979-03-21
JPS5353674A (en)	1978-05-16
NO773588L (no)	1978-04-21
PL106962B1 (pl)	1980-01-31
MX4843E (es)	1982-10-28
DE2746762A1 (de)	1978-04-27
FR2368485B1 (da)	1983-01-07
HK31081A (en)	1981-07-10
NL172062C (nl)	1983-07-01
LU78336A1 (fr)	1979-06-01
DE2746762C3 (de)	1980-08-21
NL7711471A (nl)	1978-04-24
RO74135A (ro)	1981-08-30
HU173644B (hu)	1979-07-28
IN146954B (da)	1979-10-20
FI773073A7 (fi)	1978-04-21
FR2368485A1 (fr)	1978-05-19
GB1542004A (en)	1979-03-14
JPS6139311B2 (da)	1986-09-03
MY8100275A (en)	1981-12-31
NO148713B (no)	1983-08-22
IE45715B1 (en)	1982-11-03
YU243877A (en)	1982-08-31
SE437828B (sv)	1985-03-18
US4107430A (en)	1978-08-15
BE859907A (fr)	1978-04-19
NL172062B (nl)	1983-02-01
NZ185461A (en)	1978-12-18
IE45715L (en)	1978-04-20
AR213867A1 (es)	1979-03-30
DK159314B (da)	1990-10-01
IL53056A0 (en)	1977-12-30
ATA732077A (de)	1980-05-15
FI63939B (fi)	1983-05-31
PT67171A (pt)	1977-11-01
AU499048B2 (en)	1979-04-05
PL201585A1 (pl)	1978-07-31
DE2746762B2 (de)	1979-12-13
SE7710759L (sv)	1978-04-21
BG32852A3 (bg)	1982-10-15
PH13941A (en)	1980-11-04
ES463343A1 (es)	1978-07-01
CS192494B2 (en)	1979-08-31
SU831078A3 (ru)	1981-05-15
IL53056A (en)	1981-01-30
NO148713C (no)	1983-11-30
DK159314C (da)	1991-02-25
GR69786B (da)	1982-07-07
YU40978B (en)	1986-10-31
AT360025B (de)	1980-12-10

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Legal Events

Date	Code	Title	Description
1997-11-17	PUP	Patent expired