DK465380A - Fremgangsmaade til fremstilling af azepinderivater - Google Patents

Fremgangsmaade til fremstilling af azepinderivater

Info

Publication number: DK465380A
Authority: DK; Denmark
Prior art keywords: alkyl; procedure; preparation; trifluoromethyl; alkoxy
Prior art date: 1979-11-02

Application number

DK465380A

Other languages

Danish (da)

English (en)

Inventor

F Gadient

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-11-02

Filing date

1980-10-31

Publication date

1981-05-03

1980-10-31 Application filed by Sandoz Ag filed Critical Sandoz Ag

1981-05-03 Publication of DK465380A publication Critical patent/DK465380A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK465380A 1979-11-02 1980-10-31 Fremgangsmaade til fremstilling af azepinderivater DK465380A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH985279		1979-11-02

Publications (1)

Publication Number	Publication Date
DK465380A true DK465380A (da)	1981-05-03

Family

ID=4356374

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK465380A DK465380A (da)	1979-11-02	1980-10-31	Fremgangsmaade til fremstilling af azepinderivater

Country Status (13)

Country	Link
US (1)	US4478750A (pt)
EP (1)	EP0028381B1 (pt)
JP (1)	JPS5675493A (pt)
AT (1)	ATE12641T1 (pt)
AU (1)	AU6401480A (pt)
DE (1)	DE3070467D1 (pt)
DK (1)	DK465380A (pt)
ES (1)	ES496451A0 (pt)
FI (1)	FI803356L (pt)
IL (1)	IL61382A (pt)
NZ (1)	NZ195423A (pt)
PT (1)	PT72002B (pt)
ZA (1)	ZA806741B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH649553A5 (de) *	1982-05-06	1985-05-31	Sandoz Ag	Azepinoindole und verfahren zu deren herstellung.
DE3229215A1 (de) *	1982-08-05	1984-02-09	Basf Ag, 6700 Ludwigshafen	1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
US4748247A (en) *	1986-10-21	1988-05-31	American Home Products Corporation	2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]alkyl]alkyl]pyrido- and pyrazino-indole-1,3-dione derivatives as histamine H1 antagonists
FR2663935A1 (fr) *	1990-06-27	1992-01-03	Adir	Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9025890D0 (en) *	1990-11-28	1991-01-09	Lilly Industries Ltd	Pharmaceutical compounds
US5616575A (en) *	1995-12-04	1997-04-01	Regents Of The University Of Minnesota	Bioactive tricyclic ibogaine analogs
MY122278A (en)	1999-07-19	2006-04-29	Upjohn Co	1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7030109B2 (en)	1999-07-19	2006-04-18	Pharmacia & Upjohn Company	1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
AU2001269781A1 (en) *	2000-07-06	2002-01-21	Pharmacia And Upjohn Company	Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles
AU2001292898A1 (en)	2000-09-20	2002-04-02	Brad A. Acker	Substituted azepino[4,5b)indole derivatives
US6849640B2 (en)	2001-08-08	2005-02-01	Pharmacia & Upjohn Company	Therapeutic 1H-pyrido [4,3-b] indoles
WO2018064465A1 (en)	2016-09-29	2018-04-05	The Regents Of The University Of California	Compounds for increasing neural plasticity
CN113784962B (zh)	2019-02-27	2025-04-25	加利福尼亚大学董事会	用于治疗脑部疾病的氮杂环庚三烯并-吲哚类和其他杂环
TW202333668A (zh)	2021-12-15	2023-09-01	美商德利克斯醫療公司	經苯氧基及苄氧基取代之精神成形素(psychoplastogen)及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH445512A (de) *	1964-12-03	1967-10-31	Geigy Ag J R	Verfahren zur Herstellung von neuen Indolderivaten
US3839357A (en) *	1966-05-10	1974-10-01	Upjohn Co	1,2,3,4,5,6-hexahydroazepino(4,5-b)indoles
US3553232A (en) *	1967-08-25	1971-01-05	Upjohn Co	4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones
US3652588A (en) *	1969-10-23	1972-03-28	Upjohn Co	6-alkyl-1 2 3 4 5 6-hexahydroazepino(4 5-b)indoles

1980
- 1980-10-25 DE DE8080106550T patent/DE3070467D1/de not_active Expired
- 1980-10-25 EP EP80106550A patent/EP0028381B1/en not_active Expired
- 1980-10-25 AT AT80106550T patent/ATE12641T1/de not_active IP Right Cessation
- 1980-10-27 FI FI803356A patent/FI803356L/fi not_active Application Discontinuation
- 1980-10-31 PT PT72002A patent/PT72002B/pt unknown
- 1980-10-31 ZA ZA00806741A patent/ZA806741B/xx unknown
- 1980-10-31 NZ NZ195423A patent/NZ195423A/en unknown
- 1980-10-31 ES ES496451A patent/ES496451A0/es active Granted
- 1980-10-31 AU AU64014/80A patent/AU6401480A/en not_active Abandoned
- 1980-10-31 JP JP15239780A patent/JPS5675493A/ja active Pending
- 1980-10-31 IL IL61382A patent/IL61382A/xx unknown
- 1980-10-31 DK DK465380A patent/DK465380A/da not_active Application Discontinuation
1982
- 1982-06-07 US US06/385,867 patent/US4478750A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0028381A3 (en)	1981-07-22
FI803356A7 (fi)	1981-05-03
ZA806741B (en)	1982-05-26
JPS5675493A (en)	1981-06-22
IL61382A0 (en)	1980-12-31
NZ195423A (en)	1984-07-06
EP0028381A2 (en)	1981-05-13
FI803356L (fi)	1981-05-03
EP0028381B1 (en)	1985-04-10
ES8205800A1 (es)	1982-06-16
ES496451A0 (es)	1982-06-16
PT72002A (fr)	1980-11-01
ATE12641T1 (de)	1985-04-15
IL61382A (en)	1984-02-29
DE3070467D1 (en)	1985-05-15
US4478750A (en)	1984-10-23
PT72002B (fr)	1981-12-17
AU6401480A (en)	1981-05-07

Legal Events

Date	Code	Title	Description
1986-06-30	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
NO875440L (no)	1987-12-28	Fremgangsmaate for fremstilling av kalsiumuavhengig camp-fosfodiesterase-inhibitorantidepressivt middel.
DK465380A (da)	1981-05-03	Fremgangsmaade til fremstilling af azepinderivater
FI906045A0 (fi)	1990-12-07	Kvaevehaltiga spirocykliska foereningar.
ATE32077T1 (de)	1988-02-15	7-amino-azolo(1,5-a>-pyrimidine und diese enthaltende fungizide.
ES2167371T3 (es)	2002-05-16	Derivados de 1h-3-aril-pirrolidin-2,4-diona espirociclicos substituidos.
ES2074463T3 (es)	1995-09-16	Compuestos de nitrometileno, su preparacion y su uso como pesticidas.
DE3360904D1 (de)	1985-11-07	A fungicidal indanylbenzamide
NO176911C (no)	1995-06-21	Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling
ES2039221T3 (es)	1996-07-16	Procedimiento para producir derivados de piridazinona.
SE8006953L (sv)	1981-04-04	Heterocykliska foreningar
FI833784A0 (fi)	1983-10-17	1,3,4,6,7,11b-hexahydro-7-aryl-2h-pyrazino/2,1-a/isokinoliner och foerfaranden foer framstaellning dessa
DE3667788D1 (de)	1990-02-01	Diphenyletherherbizide.
ES2017493B3 (es)	1991-02-16	Herbicidas de difenil-eter.
ES2077697T3 (es)	1995-12-01	Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
FI854343A0 (fi)	1985-11-05	Foerfarande foer framstaellning av 3-amino-2,3-dihydro-1-benzoxepinfoereningar.
IL82419A (en)	1991-06-10	3-amino-dihydropyridines,their preparation and medicaments containing them
AR245701A1 (es)	1994-02-28	Derivados de sulfamoilurea herbicidamente activos y formulacion herbicida que los contiene