DK473889A - Granula - Google Patents

Granula Download PDF

Info

Publication number
DK473889A
DK473889A DK473889A DK473889A DK473889A DK 473889 A DK473889 A DK 473889A DK 473889 A DK473889 A DK 473889A DK 473889 A DK473889 A DK 473889A DK 473889 A DK473889 A DK 473889A
Authority
DK
Denmark
Prior art keywords
granules
core
dispersion
dusting powder
produced
Prior art date
Application number
DK473889A
Other languages
Danish (da)
English (en)
Other versions
DK473889D0 (da
Inventor
Hiroyoshi Koyama
Shunichi Itoh
Shin-Ichiro Hirai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK473889D0 publication Critical patent/DK473889D0/da
Publication of DK473889A publication Critical patent/DK473889A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK473889A 1988-09-27 1989-09-26 Granula DK473889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24354388 1988-09-27

Publications (2)

Publication Number Publication Date
DK473889D0 DK473889D0 (da) 1989-09-26
DK473889A true DK473889A (da) 1990-03-28

Family

ID=17105442

Family Applications (1)

Application Number Title Priority Date Filing Date
DK473889A DK473889A (da) 1988-09-27 1989-09-26 Granula

Country Status (11)

Country Link
US (1) US5855914A (fr)
EP (1) EP0361874B1 (fr)
KR (1) KR0143424B1 (fr)
AT (1) ATE97317T1 (fr)
AU (1) AU626584B2 (fr)
CA (1) CA1338596C (fr)
DE (1) DE68910773T2 (fr)
DK (1) DK473889A (fr)
ES (1) ES2060784T3 (fr)
IE (1) IE63039B1 (fr)
NZ (1) NZ230763A (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114374D0 (en) * 1991-07-03 1991-08-21 Smithkline Beecham Plc Novel process
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
SE9600046D0 (sv) * 1996-01-05 1996-01-05 Astra Ab New pharmaceutical formulation
DE59710349D1 (de) * 1996-04-04 2003-07-31 Felix Specht Verfahren zur herstellung von gering dosierten freifliessenden und/oder direktkomprimierbaren pulversystemen
TW580397B (en) * 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
DK2263660T3 (en) * 1998-05-18 2018-01-02 Takeda Pharmaceuticals Co Orally disintegrating tablets.
ATE291418T1 (de) 1998-07-28 2005-04-15 Takeda Pharmaceutical Leicht zerfallende feste zubereitung
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
CA2313504C (fr) 1999-07-12 2007-05-29 Douglas P. Debernardi Acide folique sous formes posologiques solides
FR2796840B1 (fr) 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques Comprimes faiblement doses et procede de preparation
ES2260345T3 (es) * 2001-03-07 2006-11-01 Dainippon Sumitomo Pharma Co., Ltd. Metodo para fabricar granulos de farmacos, los granulos de farmaco y preparacion farmaceutica que contiene los granulos de farmaco.
US20070059368A1 (en) * 2005-05-31 2007-03-15 Cherukuri S R Modified release formulations of anti-irritability drugs
MY148466A (en) * 2001-10-26 2013-04-30 Merck Frosst Canada Ltd Granule formulation
US20030220351A1 (en) * 2002-05-24 2003-11-27 Gilbert Gonzales Enteric coated caffeine tablet
WO2004024168A1 (fr) * 2002-09-13 2004-03-25 Metcon Medicin Ab Composition et procede a utiliser dans des procedures de nettoyage intestinal
KR101099176B1 (ko) * 2003-01-21 2011-12-27 니뽄 신야쿠 가부시키가이샤 구강내 속붕성 정제
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
US7670624B2 (en) * 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
CA2561700A1 (fr) * 2004-04-16 2005-12-15 Santarus, Inc. Combinaison d'un inhibiteur de la pompe a protons, d'un agent tampon et d'un agent prokinetique
WO2006045152A1 (fr) * 2004-10-29 2006-05-04 Mayne Pharma International Pty Ltd Procede ameliore de preparation de comprimes
CA2599340C (fr) * 2005-02-25 2012-12-04 Takeda Pharmaceutical Company Limited Procede de fabrication de granules
US20090017110A1 (en) * 2005-05-31 2009-01-15 Capricorn Pharma Inc. Modified release formulations of anti-irritability drugs
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
EP2050439B1 (fr) * 2006-08-11 2016-11-23 Asahi Kasei Kabushiki Kaisha Procédé de production de granulé sphérique contenant une substance légèrement hydrosoluble
EP2086543A2 (fr) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprenant des agents d'inhibition de la pompe à protons labiles d'acide, au moins un autre agent pharmaceutiquement actif et leurs procédés d'utilisation
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
WO2008114800A2 (fr) * 2007-03-13 2008-09-25 Takeda Pharmaceutical Company Limited Préparation solide
CA2615137A1 (fr) * 2007-12-17 2009-06-17 Pharmascience Inc. Dispositif therapeutique monocouche a liberation controlee
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
EP3031451B1 (fr) * 2009-01-26 2018-03-07 Shin-Etsu Chemical Co., Ltd Procédé de fabrication de comprimés à granulation par voie humide utilisant une dispersion aqueuse de cellulose hydroxypropyle substituée faible
JP5823401B2 (ja) * 2010-09-13 2015-11-25 大鵬薬品工業株式会社 不快な味が遮蔽された薬物含有膜被覆粒子
EP2674149B1 (fr) 2012-06-15 2017-10-04 Shin-Etsu Chemical Co., Ltd. Procédé de préparation de granules composites comprenant de la cellulose hydroxypropyle faiblement substituée et préparation à libération rapide
US20170182070A1 (en) 2014-10-08 2017-06-29 Mayne Pharma International Pty Ltd. Controlled Release Doxycycline
WO2016174664A1 (fr) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Compositions à désintégration par voie orale
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CA3133599A1 (fr) * 2019-03-28 2020-10-01 Omniactive Health Technologies Limited Formulations de cafeine a liberation pulsee et leur procede de preparation
CN110200935B (zh) * 2019-06-03 2021-03-02 浙江得恩德制药股份有限公司 一种胶体果胶铋胶囊及其制备工艺

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3664963A (en) * 1969-10-22 1972-05-23 Balchem Corp Encapsulation process
SE426548B (sv) * 1978-12-05 1983-01-31 Haessle Ab Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer
JPS5826816A (ja) * 1981-08-11 1983-02-17 Teisan Seiyaku Kk 球形顆粒からなる持続性複合顆粒剤
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
GB8507779D0 (en) * 1985-03-26 1985-05-01 Fujisawa Pharmaceutical Co Drug carrier
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US4704285A (en) * 1985-11-18 1987-11-03 The Dow Chemical Company Sustained release compositions comprising hydroxypropyl cellulose ethers
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
JP2536109B2 (ja) * 1988-12-19 1996-09-18 ライオン株式会社 毛髪化粧料

Also Published As

Publication number Publication date
US5855914A (en) 1999-01-05
EP0361874A3 (fr) 1991-01-30
EP0361874B1 (fr) 1993-11-18
DK473889D0 (da) 1989-09-26
KR900004325A (ko) 1990-04-12
IE893075L (en) 1990-03-27
DE68910773D1 (de) 1993-12-23
AU4233289A (en) 1990-04-05
ATE97317T1 (de) 1993-12-15
ES2060784T3 (es) 1994-12-01
EP0361874A2 (fr) 1990-04-04
KR0143424B1 (ko) 1998-07-15
CA1338596C (fr) 1996-09-17
IE63039B1 (en) 1995-03-22
DE68910773T2 (de) 1994-05-11
NZ230763A (en) 1991-10-25
AU626584B2 (en) 1992-08-06

Similar Documents

Publication Publication Date Title
DK473889A (da) Granula
FI863074A7 (fi) Farmaseuttisesti aktiivisten aineiden rakeinen, hidasluovutteinen muoto.
IL87866A0 (en) 2-anilinopyrimidine derivatives,their preparation and their use as pesticides
DE68910297D1 (de) Homogenes, granuliertes Stickstoffdüngemittel.
IL86098A0 (en) (p-phenoxyphenoxy)-methyl-five-membered heteroaromatic compounds,their preparation and their use as pesticides
EG19572A (en) Pyrimidine derivatives their production and herbicides containing the same as an active ingredient
IT8947598A0 (it) Composti carbonilati, loro preparazione e loro impiego come erbicidi
IL110921A0 (en) Substituted pyridines, their preparation and their use as pesticides and fungicides
ZA9110135B (en) 2-aryl-5-(trifluoromethyl)-2-pyrroline compounds and process for the manufacture of insecticidal,2-aryl-1-(alkoxymethyl)-4-halo-5-(trifluoromethyl)pyrroles
HUT49875A (en) Herbicides comprising substituted sulfonylaminoazole derivatives as active ingredient and process for producing the active ingredients
FI891865A7 (fi) Atselastiinia sisältäviä lääkkeitä, joista vaikuttava aine vapautuu säädellysti
AU590915B2 (en) N-pyridyloxyphenylisothioureas,their production and use as pesticides.
IL90939A0 (en) Substituted imidazolyl-methyloxiranes and substituted imidazolylpropenes,their preparation and their use as fungicides
IL85234A0 (en) 1-aminomethyl-3-aryl-4-cyanopyrroles,their preparation and their use as pesticides
IL85195A0 (en) Benzoylurea derivative,its production and insecticide composition containing the same
IL86614A0 (en) Heterocyclic compounds,their manufacture and their use as pesticides
NO901396L (no) Fytosanitaere preparater, deres fremstilling og deres anvendelse for behandling av kryptogame sykdommer.
AU4614289A (en) Substituted pyridazinones, processes for their preparation, and their use as pesticides
IL110920A0 (en) Substituted pyridines, their preparation and their use as pesticides and fungicides
NO893768L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 2,7-diamino-1,2,3,4-tetrahydronaftalenderivater.
NO894645L (no) Fremgangsmaate for aa hemme geldannelse av umettede monomerer, blandinger omfattende nevnte monomerer og deres anvendelse.
HUT46881A (en) Herbicides comprising cyclohexane-1,3,5-triones as active ingredient and process for producing the active ingredients
IL87183A0 (en) Substituted bicyclic compounds,their preparation and their use as pesticides
GR3018795T3 (en) Emulsion-free emulsion polymers in sustained-release pharmaceutical compositions and their production
DK83988A (da) Pesticide bicyclooctaner, deres fremstilling og midler indeholdende forbindelserne.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment