DK49077A - Piperazinderivater samt fremgangsmade til fremstilling deraf - Google Patents

Piperazinderivater samt fremgangsmade til fremstilling deraf

Info

Publication number: DK49077A
Authority: DK; Denmark
Prior art keywords: procedures; preparation; piperazine derivatives; piperazine; derivatives
Prior art date: 1976-02-07

Application number

DK49077A

Other languages

English (en)

Other versions

DK138891B (da

DK138891C (da

Inventor

R Cyrus

M Raschack

Original Assignee

Knoll Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-02-07

Filing date

1977-02-04

Publication date

1977-08-08

1977-02-04 Application filed by Knoll Ag filed Critical Knoll Ag

1977-08-08 Publication of DK49077A publication Critical patent/DK49077A/da

1978-11-13 Publication of DK138891B publication Critical patent/DK138891B/da

1979-04-23 Application granted granted Critical

1979-04-23 Publication of DK138891C publication Critical patent/DK138891C/da

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)

DK49077A 1976-02-07 1977-02-04 Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer DK138891C (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19762604845 DE2604845A1 (de)	1976-02-07	1976-02-07	Neue piperazinderivate

Publications (3)

Publication Number	Publication Date
DK49077A true DK49077A (da)	1977-08-08
DK138891B DK138891B (da)	1978-11-13
DK138891C DK138891C (da)	1979-04-23

Family

ID=5969327

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK49077A DK138891C (da)	1976-02-07	1977-02-04	Analogifremgangsmaade til fremstilling af 3-methyl-3-(3,4-dihydroxybenzyl)-piperazinderivater eller deres salte med fysiologisk anvendelige syrer

Country Status (25)

Country	Link
US (1)	US4079137A (da)
JP (1)	JPS52105186A (da)
AT (1)	AT355578B (da)
AU (1)	AU504526B2 (da)
BE (1)	BE850492A (da)
CA (1)	CA1094560A (da)
CH (1)	CH631448A5 (da)
CS (1)	CS201544B2 (da)
DD (1)	DD128133A5 (da)
DE (1)	DE2604845A1 (da)
DK (1)	DK138891C (da)
ES (1)	ES455691A1 (da)
FI (1)	FI63226C (da)
FR (1)	FR2340311A1 (da)
GB (1)	GB1550545A (da)
HU (1)	HU173483B (da)
IE (1)	IE44339B1 (da)
IL (1)	IL51316A (da)
LU (1)	LU76706A1 (da)
NL (1)	NL7700841A (da)
NO (1)	NO142625C (da)
PL (1)	PL105526B1 (da)
PT (1)	PT66154B (da)
SE (1)	SE7701187L (da)
ZA (1)	ZA77248B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4341698A (en) *	1979-06-21	1982-07-27	Richardson-Merrell Inc.	Enkaphalin derivatives
US4483988A (en) *	1980-03-14	1984-11-20	Richardson Merrell Inc.	Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones
US4766125A (en) *	1981-06-23	1988-08-23	Janssen Pharmaceutica N.V.	N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
WO2006062917A2 (en) *	2004-12-06	2006-06-15	Sciclone Pharmaceuticals, Inc.	Alpha thymosin peptides as cancer vaccine adjuvants
US20080300166A1 (en) *	2007-06-01	2008-12-04	Sciclone Pharmaceuticals, Inc.	Treatment of Melanoma with Alpha Thymosin Peptides
WO2009075813A1 (en) *	2007-12-12	2009-06-18	Sciclone Pharmaceuticals, Inc.	Treatment of melanoma with alpha thymosin peptides in combination with antibodies against cytotoxic t lymphocyte-associated antigen 4 (ctla4)
WO2009076587A1 (en) *	2007-12-13	2009-06-18	Sciclone Pharmaceuticals, Inc.	Treatment of melanoma with alpha thymosin peptides in combination with a kinase inhibitor
JP2011506467A (ja) *	2007-12-14	2011-03-03	サイクローン・ファーマシューティカルズ・インコーポレイテッド	抗悪性腫瘍性熱ショックアポトーシス活性化因子（ｈｓａａ）と組み合わせられたアルファチモシンペプチドによる黒色腫の処置の方法
US8829173B2 (en)	2008-09-26	2014-09-09	Tocagen Inc.	Recombinant vectors
JP2012526149A (ja) *	2009-05-08	2012-10-25	サイクローン・ファーマシューティカルズ・インコーポレイテッド	ワクチン増強剤としてのαチモシンペプチド
CN107148279B (zh)	2014-10-21	2021-09-03	赛生药品股份国际有限公司	用免疫刺激剂治疗癌症

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3472856A (en) *	1967-05-29	1969-10-14	Sterling Drug Inc	1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines
DE2438725A1 (de) *	1974-08-12	1976-02-26	Knoll Ag	Piperazinderivate
US4031216A (en) *	1974-08-12	1977-06-21	Knoll A.G. Chemische Fabriken	3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines

1976
- 1976-02-07 DE DE19762604845 patent/DE2604845A1/de not_active Withdrawn
1977
- 1977-01-17 ZA ZA770248A patent/ZA77248B/xx unknown
- 1977-01-18 BE BE174169A patent/BE850492A/xx not_active IP Right Cessation
- 1977-01-19 US US05/760,722 patent/US4079137A/en not_active Expired - Lifetime
- 1977-01-24 GB GB2736/77A patent/GB1550545A/en not_active Expired
- 1977-01-24 IL IL51316A patent/IL51316A/xx unknown
- 1977-01-27 NL NL7700841A patent/NL7700841A/xx not_active Application Discontinuation
- 1977-02-01 IE IE205/77A patent/IE44339B1/en unknown
- 1977-02-03 AT AT68177A patent/AT355578B/de not_active IP Right Cessation
- 1977-02-03 SE SE7701187A patent/SE7701187L/xx not_active Application Discontinuation
- 1977-02-03 CS CS77726A patent/CS201544B2/cs unknown
- 1977-02-03 CH CH132077A patent/CH631448A5/de not_active IP Right Cessation
- 1977-02-04 PL PL1977195809A patent/PL105526B1/pl unknown
- 1977-02-04 PT PT66154A patent/PT66154B/pt unknown
- 1977-02-04 LU LU76706A patent/LU76706A1/xx unknown
- 1977-02-04 CA CA271,087A patent/CA1094560A/en not_active Expired
- 1977-02-04 AU AU21952/77A patent/AU504526B2/en not_active Expired
- 1977-02-04 NO NO770374A patent/NO142625C/no unknown
- 1977-02-04 HU HU77KO2845A patent/HU173483B/hu unknown
- 1977-02-04 DK DK49077A patent/DK138891C/da active
- 1977-02-04 DD DD7700197240A patent/DD128133A5/xx unknown
- 1977-02-05 ES ES455691A patent/ES455691A1/es not_active Expired
- 1977-02-07 FI FI770398A patent/FI63226C/fi not_active IP Right Cessation
- 1977-02-07 JP JP1235677A patent/JPS52105186A/ja active Pending
- 1977-02-07 FR FR7703386A patent/FR2340311A1/fr active Granted

Also Published As

Publication number	Publication date
FI63226B (fi)	1983-01-31
CS201544B2 (en)	1980-11-28
FR2340311B1 (da)	1980-02-08
IL51316A0 (en)	1977-03-31
NO142625C (no)	1980-09-17
IE44339L (en)	1977-08-07
FI770398A7 (da)	1977-08-08
US4079137A (en)	1978-03-14
DD128133A5 (de)	1977-11-02
SE7701187L (sv)	1977-08-08
PL105526B1 (pl)	1979-10-31
NO142625B (no)	1980-06-09
CH631448A5 (de)	1982-08-13
NL7700841A (nl)	1977-08-09
ATA68177A (de)	1979-08-15
PT66154B (fr)	1978-07-07
JPS52105186A (en)	1977-09-03
DK138891B (da)	1978-11-13
ZA77248B (en)	1977-11-30
PT66154A (fr)	1977-03-01
IE44339B1 (en)	1981-10-21
IL51316A (en)	1980-12-31
AT355578B (de)	1980-03-10
DK138891C (da)	1979-04-23
CA1094560A (en)	1981-01-27
FI63226C (fi)	1983-05-10
DE2604845A1 (de)	1977-08-18
HU173483B (hu)	1979-05-28
GB1550545A (en)	1979-08-15
AU504526B2 (en)	1979-10-18
BE850492A (fr)	1977-07-18
LU76706A1 (da)	1977-06-28
ES455691A1 (es)	1978-01-01
AU2195277A (en)	1978-08-10
NO770374L (no)	1977-08-09
FR2340311A1 (fr)	1977-09-02

Publication	Publication Date	Title
DK20979A (da)	1979-07-21	4-amino-5-alkylsulfonyl-0-anisamid-derivater samt fremgangsmaade til fremstilling deraf
SE416083B (sv)	1980-11-24	Forfalskningssekert dokument samt forfarande for framstellning av detsamma
DK282880A (da)	1981-01-04	Aminoalkylbenzen-derivater samt fremgangsmaade til fremstilling deraf
DK119577A (da)	1977-09-24	Peptid samt fremgangsmade til fremstilling deraf
DK397777A (da)	1978-03-09	Thiazolindinderivater samt fremgangsmaade til fremstilling deraf
DK291180A (da)	1981-01-07	Indolizinderivater samt fremgangsmaade til fremstilling deraf
DK540678A (da)	1979-07-06	Polypeptider samt fremgangsmaade til fremstilling heraf
DK37278A (da)	1978-07-28	Meta-sulfonamido-benzamid-derivater samt fremgangsmaade til fremstilling deraf
DK223180A (da)	1980-11-24	3-formylmethylcephalosporiner samt fremgangsmaade til fremstilling heraf
DK147378A (da)	1978-10-05	Imidazodiazepinderivater samt fremgangsmaade til fremstilling deraf
DK25177A (da)	1977-07-25	1,2-benzisothiazolinoner-3 samt fremgangsmade til fremstilling deraf
SE7601962L (sv)	1976-08-23	Tetralon- och indanon-derivat samt forfarande for framstellning derav
DK545077A (da)	1978-06-09	Thiooximcephalosporin- og penicillinderivater samt fremgangsmaader til fremstilling deraf
GB1550545A (en)	1979-08-15	Piperazine derivatives
SE7704322L (sv)	1977-10-16	Tiokarbamidderivat samt forfarande for framstellning derav
DK303178A (da)	1979-01-07	Benzylpyrimidiner samt fremgangsmaade til fremstilling deraf
SE7711246L (sv)	1978-04-08	Piperazinderivat
DK402877A (da)	1978-04-06	1-amino-2-hydroxy-3-heterocyclyloxy-propansalte deraf samt fremgangsmaade til fremstilling deraf
DK29876A (da)	1976-07-28	Svovlholdige octapeptidderivater samt fremgangsmade til fremstilling heraf
DK206377A (da)	1977-11-16	Substituerede pyrazolopyriminer fremgangsmade til deres fremstilling samt deres anvendelse
DK170779A (da)	1979-10-27	Phenoxyalkyltrialkoxysilaner samt fremgangsmaade til fremstilling heraf
DK159160C (da)	1991-02-18	Nitroaryl-malto-n-osider samt fremgangsmaade til fremstilling deraf
NL7812132A (nl)	1979-07-03	5.6-dihydroprostacyclinederivaten en werkwijzen ter bereiding ervan.
DK313576A (da)	1977-01-13	1-methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoler samt fremgangsmade til fremstilling deraf
FI773951A7 (fi)	1978-07-01	Isokinolinacetamid-derivat