DK495886A - Carboxamidderivater - Google Patents

Carboxamidderivater Download PDF

Info

Publication number: DK495886A
Authority: DK; Denmark
Prior art keywords: carboxamide
Prior art date: 1985-10-17

Application number

DK495886A

Other languages

English (en)

Other versions

DK495886D0 (da

DK169964B1 (da

Inventor

Peter Robert Bernstein

Frederick Jeffrey Brown

Victor Giulio Matassa

Ying Kwong Yee

Original Assignee

Ici America Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-17

Filing date

1986-10-16

Publication date

1987-04-18

1985-10-17 Priority claimed from GB858525658A external-priority patent/GB8525658D0/en

1986-04-15 Priority claimed from GB868609176A external-priority patent/GB8609176D0/en

1986-10-16 Application filed by Ici America Inc filed Critical Ici America Inc

1986-10-16 Publication of DK495886D0 publication Critical patent/DK495886D0/da

1987-04-18 Publication of DK495886A publication Critical patent/DK495886A/da

1995-04-18 Application granted granted Critical

1995-04-18 Publication of DK169964B1 publication Critical patent/DK169964B1/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Immunology (AREA)
Cardiology (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK495886A 1985-10-17 1986-10-16 Amidiske indol- eller indazolderivater og farmaceutisk acceptable salte deraf, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem DK169964B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB8525658		1985-10-17
GB858525658A GB8525658D0 (en)	1985-10-17	1985-10-17	Heterocyclic amide derivatives
GB868609176A GB8609176D0 (en)	1986-04-15	1986-04-15	Carboxamide derivatives
GB8609176		1986-04-15

Publications (3)

Publication Number	Publication Date
DK495886D0 DK495886D0 (da)	1986-10-16
DK495886A true DK495886A (da)	1987-04-18
DK169964B1 DK169964B1 (da)	1995-04-18

Family

ID=26289900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK495886A DK169964B1 (da)	1985-10-17	1986-10-16	Amidiske indol- eller indazolderivater og farmaceutisk acceptable salte deraf, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem

Country Status (19)

Country	Link
US (3)	US4918094A (da)
EP (1)	EP0220066B1 (da)
JP (1)	JP2512724B2 (da)
KR (1)	KR900004385B1 (da)
AU (1)	AU595839B2 (da)
CA (1)	CA1336192C (da)
DE (1)	DE3684549D1 (da)
DK (1)	DK169964B1 (da)
ES (1)	ES2032384T3 (da)
FI (1)	FI83866C (da)
GB (1)	GB8623429D0 (da)
GR (1)	GR3004137T3 (da)
HK (1)	HK18197A (da)
HU (1)	HU197724B (da)
IE (1)	IE60480B1 (da)
IL (1)	IL80335A (da)
NO (1)	NO170482C (da)
NZ (1)	NZ217962A (da)
PT (1)	PT83558B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK496086A (da) *	1985-10-17	1987-04-18	Ici America Inc	Heterocykliske forbindelser
US5041460A (en) *	1988-04-14	1991-08-20	Ici Americas Inc.	Heter-aliphatic carboxamides
GB8927981D0 (en) *	1989-12-11	1990-02-14	Ici Plc	Carbamoyl derivative
US5286740A (en) *	1989-12-11	1994-02-15	Imperial Chemical Industries Plc	Carbamoyl derivatives
DK0455596T3 (da) *	1990-05-04	1994-11-28	Ciba Geigy Ag	Substituerede indoler
US5095031A (en) *	1990-08-20	1992-03-10	Abbott Laboratories	Indole derivatives which inhibit leukotriene biosynthesis
GB9026427D0 (en) *	1990-12-05	1991-01-23	Ici Plc	Chemical process
US5239083A (en) *	1991-03-11	1993-08-24	Kyowa Hakko Kogyo Co., Ltd.	Indole derivatives which inhibit steroid 5α reductase
GB9119001D0 (en) *	1991-09-05	1991-10-23	Ici Plc	Pharmaceutical agents
EP0539329A1 (de) *	1991-10-25	1993-04-28	Ciba-Geigy Ag	Acetylen-Verbindungen, verwendbar als Leukotrien-Antagonisten
ATE122656T1 (de) *	1991-10-25	1995-06-15	Ciba Geigy Ag	Verfahren zur herstellung substituierter indole.
ES2050611B1 (es) *	1992-10-08	1994-12-16	Ici Plc	Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
US5288743A (en) *	1992-11-20	1994-02-22	Abbott Laboratories	Indole carboxylate derivatives which inhibit leukotriene biosynthesis
WO2001007031A1 (en) *	1999-07-26	2001-02-01	Shionogi & Co., Ltd.	Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same
US6614627B1 (en) *	2000-02-14	2003-09-02	Hitachi, Ltd.	Magnetic disk apparatus
JP2012521429A (ja) *	2009-03-23	2012-09-13	メルク・シャープ・エンド・ドーム・コーポレイション	疼痛治療用のｐ２ｘ３受容体アンタゴニスト
JP2020111510A (ja) *	2017-03-29	2020-07-27	科研製薬株式会社	インダゾール誘導体及びそれを含有する医薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3271416A (en) *	1961-10-24	1966-09-06	Merck & Co Inc	Indolyl aliphatic acids
FR4035M (da) *	1964-11-04	1966-03-28
FR7631M (da) *	1968-08-13	1970-01-26
US3470298A (en) *	1969-01-29	1969-09-30	Acraf	Topical anti-inflammatory composition containing (indazole-3-yl)-oxyalkanoic acids
BE738727A (en) *	1969-09-11	1970-02-16		Anti inflammatory analgesic and antipyretic indolyalkanoic - acids and derivs
DE2854987A1 (de) *	1978-12-20	1980-06-26	Boehringer Mannheim Gmbh	Diagnostische mittel zum nachweis proteolytischer enzyme und dafuer geeignete chromogene
IE54269B1 (en) *	1981-12-30	1989-08-02	Ici America Inc	Pharmaceutically active phenylcarboxylic acid derivatives
CA1241660A (en) *	1984-06-25	1988-09-06	Yvan Guindon	Indole-2-alkanoic acids
GB8426474D0 (en) *	1984-10-19	1984-11-28	Ici America Inc	Heterocyclic amides
GB8524157D0 (en) *	1984-10-19	1985-11-06	Ici America Inc	Heterocyclic amides
GB8607294D0 (en) *	1985-04-17	1986-04-30	Ici America Inc	Heterocyclic amide derivatives

1986
- 1986-09-30 GB GB868623429A patent/GB8623429D0/en active Pending
- 1986-10-16 EP EP86308054A patent/EP0220066B1/en not_active Expired - Lifetime
- 1986-10-16 PT PT83558A patent/PT83558B/pt not_active IP Right Cessation
- 1986-10-16 KR KR1019860008670A patent/KR900004385B1/ko not_active Expired
- 1986-10-16 DK DK495886A patent/DK169964B1/da not_active IP Right Cessation
- 1986-10-16 AU AU63985/86A patent/AU595839B2/en not_active Ceased
- 1986-10-16 ES ES198686308054T patent/ES2032384T3/es not_active Expired - Lifetime
- 1986-10-16 IL IL80335A patent/IL80335A/xx not_active IP Right Cessation
- 1986-10-16 DE DE8686308054T patent/DE3684549D1/de not_active Expired - Lifetime
- 1986-10-16 IE IE273886A patent/IE60480B1/en not_active IP Right Cessation
- 1986-10-16 NO NO864130A patent/NO170482C/no not_active IP Right Cessation
- 1986-10-16 NZ NZ217962A patent/NZ217962A/xx unknown
- 1986-10-16 US US06/919,845 patent/US4918094A/en not_active Expired - Lifetime
- 1986-10-16 FI FI864191A patent/FI83866C/fi not_active IP Right Cessation
- 1986-10-16 HU HU864302A patent/HU197724B/hu not_active IP Right Cessation
- 1986-10-16 JP JP61246448A patent/JP2512724B2/ja not_active Expired - Lifetime
- 1986-10-17 CA CA000520794A patent/CA1336192C/en not_active Expired - Fee Related
1989
- 1989-12-29 US US07/458,876 patent/US5049576A/en not_active Expired - Lifetime
- 1989-12-29 US US07/458,868 patent/US5049679A/en not_active Expired - Lifetime
1992
- 1992-03-26 GR GR910401149T patent/GR3004137T3/el unknown
1997
- 1997-02-13 HK HK18197A patent/HK18197A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPS6299359A (ja)	1987-05-08
KR870003983A (ko)	1987-05-06
KR900004385B1 (ko)	1990-06-23
IE60480B1 (en)	1994-07-13
FI864191A7 (fi)	1987-04-18
CA1336192C (en)	1995-07-04
EP0220066A3 (en)	1988-10-12
AU6398586A (en)	1987-04-30
FI83866B (fi)	1991-05-31
FI864191A0 (fi)	1986-10-16
HK18197A (en)	1997-02-13
DK495886D0 (da)	1986-10-16
NO170482C (no)	1992-10-21
EP0220066B1 (en)	1992-03-25
EP0220066A2 (en)	1987-04-29
HUT42441A (en)	1987-07-28
PT83558A (en)	1986-11-01
NO864130L (no)	1987-04-21
GB8623429D0 (en)	1986-11-05
US5049679A (en)	1991-09-17
ES2032384T3 (es)	1993-02-16
GR3004137T3 (da)	1993-03-31
NO864130D0 (no)	1986-10-16
IL80335A (en)	1990-02-09
IE862738L (en)	1987-04-17
HU197724B (en)	1989-05-29
NZ217962A (en)	1990-03-27
FI83866C (fi)	1991-09-10
JP2512724B2 (ja)	1996-07-03
NO170482B (no)	1992-07-13
AU595839B2 (en)	1990-04-12
US4918094A (en)	1990-04-17
PT83558B (pt)	1989-05-31
US5049576A (en)	1991-09-17
DK169964B1 (da)	1995-04-18
DE3684549D1 (de)	1992-04-30

Legal Events

Date	Code	Title	Description
1995-04-18	B1	Patent granted (law 1993)
2004-06-07	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK495886D0 (da)	1986-10-16	Carboxamidderivater
ATA155686A (de)	1993-04-15	Giesspfannenkopf
AT386920B (de)	1988-11-10	Maishaecksler
ATA122686A (de)	1989-12-15	Kettenschloss
ATA257585A (de)	1988-04-15	Ru-deruebungsgeraet
ATA173385A (de)	1987-03-15	Stiegenlift
BR8501248A (pt)	1986-10-29	Sulcador pontiagudo
FR2597409B1 (fr)	1988-08-19	Lanopoudrographie
BR8505898A (pt)	1986-02-04	Altenador magnetonomo
BR8505025A (pt)	1987-05-19	Bucha
BR6500852U (pt)	1987-02-10	Churrasqueira-espeto
BR6501852U (pt)	1987-06-23	Control-temper
BR8503311A (pt)	1987-02-17	Cistotomico
BR6501182U (pt)	1987-03-24	Bonequinho
BR8501720A (pt)	1985-09-17	Semeadeira-adubadeira
ATA8786A (de)	1990-12-15	Heukran
BR6501018U (pt)	1987-03-04	Kit-box
BR6500483U (pt)	1986-11-25	Dialisor
BR6500432U (pt)	1986-11-18	Polainas
BR8505459A (pt)	1986-05-13	Poli-cacamba-pa
BR6501802U (pt)	1987-06-16	Mini-luminaria
BR8501687A (pt)	1986-11-11	Phonex
BR6501484U (pt)	1987-02-17	Vasilhame
BR8500544A (pt)	1986-09-09	Bi-telefone
BR8505432A (pt)	1987-06-02	Lenco boca-a-boca