DK506683A - Fibrinolytiske enzymer, fremgangsmaader til fremstilling deraf og farmaceutiske midler indeholdende dem - Google Patents

Fibrinolytiske enzymer, fremgangsmaader til fremstilling deraf og farmaceutiske midler indeholdende dem Download PDF

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Publication number
DK506683A
DK506683A DK506683A DK506683A DK506683A DK 506683 A DK506683 A DK 506683A DK 506683 A DK506683 A DK 506683A DK 506683 A DK506683 A DK 506683A DK 506683 A DK506683 A DK 506683A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
pharmaceutical agents
agents containing
fibrinolytic enzymes
Prior art date
Application number
DK506683A
Other languages
English (en)
Other versions
DK163134B (da
DK506683D0 (da
DK163134C (da
Inventor
Anthony Atkinson
Asgar Electricwala
John Bryan Griffiths
Amy Latter
Patrick Anthony Riley
Peter Morgan Sutton
Original Assignee
Health Lab Service Board
Univ London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Lab Service Board, Univ London filed Critical Health Lab Service Board
Publication of DK506683A publication Critical patent/DK506683A/da
Publication of DK506683D0 publication Critical patent/DK506683D0/da
Publication of DK163134B publication Critical patent/DK163134B/da
Application granted granted Critical
Publication of DK163134C publication Critical patent/DK163134C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/75Fibrin; Fibrinogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK506683A 1982-03-05 1983-11-04 Fremgangsmaade til fremstilling af et enzym med fibrinolytisk aktivitet og/eller aktivitet som en plasminogenaktivator DK163134C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8206576 1982-03-05
GB8206576 1982-03-05
PCT/GB1983/000067 WO1983003101A1 (en) 1982-03-05 1983-03-04 New fibrinolytic enzymes, methods for their production and pharmaceutical compositions containing them
GB8300067 1983-03-04

Publications (4)

Publication Number Publication Date
DK506683A true DK506683A (da) 1983-11-04
DK506683D0 DK506683D0 (da) 1983-11-04
DK163134B DK163134B (da) 1992-01-20
DK163134C DK163134C (da) 1992-06-09

Family

ID=10528816

Family Applications (1)

Application Number Title Priority Date Filing Date
DK506683A DK163134C (da) 1982-03-05 1983-11-04 Fremgangsmaade til fremstilling af et enzym med fibrinolytisk aktivitet og/eller aktivitet som en plasminogenaktivator

Country Status (18)

Country Link
US (1) US4780412A (da)
EP (1) EP0104194B1 (da)
JP (1) JPS59500351A (da)
AT (1) ATE32232T1 (da)
AU (2) AU567491B2 (da)
BR (1) BR8306108A (da)
CA (1) CA1213231A (da)
DE (1) DE3375491D1 (da)
DK (1) DK163134C (da)
FI (1) FI76375C (da)
HU (1) HU200792B (da)
IE (1) IE54593B1 (da)
IT (1) IT1194148B (da)
NO (1) NO161445C (da)
RO (1) RO88552A (da)
SU (1) SU1507204A3 (da)
WO (1) WO1983003101A1 (da)
ZA (1) ZA831399B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
JPS60158115A (ja) * 1984-01-30 1985-08-19 Meiji Milk Prod Co Ltd プラズミノーゲンアクチベーターの製造法
EP0151996B1 (en) * 1984-01-30 1991-04-03 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a double-chain plasminogen activator
US4661453A (en) * 1984-06-19 1987-04-28 American Biogenetic Sciences, Inc. Production of tissue plasminogen activator factor
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
NO171344C (no) * 1985-05-28 1993-03-03 Wellcome Found Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator
DE3722522A1 (de) * 1987-07-08 1989-01-19 Boehringer Ingelheim Int Verwendung eines vehikels mit hoher affinitaet zu tumoren
GB8723082D0 (en) * 1987-10-01 1987-11-04 Porton Prod Ltd Enzyme production
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
GB9000629D0 (en) * 1990-01-11 1990-03-14 Porton Prod Ltd Tissue plasminogen activator
IT1245485B (it) * 1991-05-03 1994-09-20 Butterfly Srl Membrane permselettive e loro impiego

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
IT1170913B (it) * 1981-04-23 1987-06-03 Manetti & Roberts Italo Brit Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
NZ206699A (en) * 1982-12-30 1989-08-29 Bio Response Inc Process for the production of serum independent cell lines

Also Published As

Publication number Publication date
RO88552A (ro) 1986-02-28
NO161445C (no) 1989-08-16
AU567491B2 (en) 1987-11-26
AU1214688A (en) 1988-09-08
FI76375C (fi) 1988-10-10
SU1507204A3 (ru) 1989-09-07
DE3375491D1 (en) 1988-03-03
CA1213231A (en) 1986-10-28
HU200792B (en) 1990-08-28
DK163134B (da) 1992-01-20
NO834024L (no) 1983-11-04
DK506683D0 (da) 1983-11-04
DK163134C (da) 1992-06-09
JPS59500351A (ja) 1984-03-08
AU625283B2 (en) 1992-07-09
NO161445B (no) 1989-05-08
EP0104194A1 (en) 1984-04-04
BR8306108A (pt) 1984-01-17
IT8319914A0 (it) 1983-03-04
AU1337783A (en) 1983-10-18
WO1983003101A1 (en) 1983-09-15
FI834042A0 (fi) 1983-11-03
IE54593B1 (en) 1989-12-06
IT1194148B (it) 1988-09-14
ATE32232T1 (de) 1988-02-15
US4780412A (en) 1988-10-25
EP0104194B1 (en) 1988-01-27
ZA831399B (en) 1984-02-29
FI76375B (fi) 1988-06-30
IT8319914A1 (it) 1984-09-04
FI834042L (fi) 1983-11-03
IE830480L (en) 1983-09-05

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