DK509579A - Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling - Google Patents

Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling

Info

Publication number
DK509579A
DK509579A DK509579A DK509579A DK509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A
Authority
DK
Denmark
Prior art keywords
preparation
intermediates
glycolipid compounds
glycolipid
compounds
Prior art date
Application number
DK509579A
Other languages
English (en)
Inventor
R L Bugianesi
M M Ponpipom
T-Y Shen
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK509579A publication Critical patent/DK509579A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK509579A 1978-12-01 1979-11-30 Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling DK509579A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/965,559 US4229441A (en) 1978-12-01 1978-12-01 Immunologic adjuvant

Publications (1)

Publication Number Publication Date
DK509579A true DK509579A (da) 1980-06-02

Family

ID=25510144

Family Applications (1)

Application Number Title Priority Date Filing Date
DK509579A DK509579A (da) 1978-12-01 1979-11-30 Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling

Country Status (6)

Country Link
US (1) US4229441A (da)
EP (1) EP0012083A1 (da)
JP (1) JPS5589298A (da)
AU (1) AU5300979A (da)
CA (1) CA1147722A (da)
DK (1) DK509579A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259324A (en) * 1979-07-31 1981-03-31 Merck & Co., Inc. Immunologic adjuvant thio glycoside compounds and compositions
JPS59118053A (ja) * 1982-12-24 1984-07-07 Hayashibara Biochem Lab Inc 飲食物とその製造方法
EP0224173B1 (en) 1985-11-25 1993-04-28 Merck & Co. Inc. Steroidal glycolipids as host resistance stimulators
US4652553A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators
US4652637A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids
HU198216B (en) * 1986-05-12 1989-08-28 Kanto Ishi Pharma Co Ltd Process for producing sialosyl-cholesterin and pharmaceutical compositions containing them as active components
US5019568A (en) * 1987-06-18 1991-05-28 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US4970199A (en) * 1987-06-18 1990-11-13 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US4942154A (en) * 1987-06-18 1990-07-17 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
JP2955314B2 (ja) * 1988-10-27 1999-10-04 リージェンツ・オブ・ザ・ユニバーシティー・オブ・ミネソタ Il―2含有リポソーム免疫アジュバント
JPH04300891A (ja) * 1991-03-29 1992-10-23 Nisshin Oil Mills Ltd:The S−グリコシドを有するガングリオシド類縁体
US5514784A (en) * 1993-03-19 1996-05-07 Wong; Chi-Huey Thio linked glycosyl compounds
US5660855A (en) * 1995-02-10 1997-08-26 California Institute Of Technology Lipid constructs for targeting to vascular smooth muscle tissue
US5695738A (en) * 1995-06-15 1997-12-09 Glycomed Incorporated Steroidal C-glycosides
WO1998009650A1 (en) * 1996-09-06 1998-03-12 Mitsubishi Chemical Corporation Vaccinal preparations
JPH11199598A (ja) * 1998-01-08 1999-07-27 Yokohama Kokusai Bio Kenkyusho:Kk ウルソデオキシコール酸誘導体とその製造法
WO1999052931A1 (fr) 1998-04-10 1999-10-21 Mitsubishi Chemical Corporation Dispersion solide contenant un derive d'acide sialique
ATE420887T1 (de) * 2003-04-02 2009-01-15 Us Gov Health & Human Serv Cholesterol enthaltende verbindungen und deren verwendung als immunogen gegen borellia burgdorferi

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050517A (en) * 1955-06-22 1962-08-21 Burroughs Wellcome Co Purine 6-thio-glycosides
US3585186A (en) * 1969-01-31 1971-06-15 American Cyanamid Co Preparation of glycopyranosiduronides and glycopyranosides and products resulting therefrom
DE2052634A1 (de) * 1970-10-27 1972-05-04 Dr Karl Thomae GmbH, 7950 Biberach Neue durch einen Steroidrest substi tuierte Derivate der Acrylsäure und Ver fahren zu ihrer Herstellung
JPS5428830A (en) * 1977-08-09 1979-03-03 Ichirou Azuma Immunological treating agent of tumor containing glycolipid as effective component
US4096247A (en) * 1977-02-16 1978-06-20 Smithkline Corporation Gold thio glucopyranoside compounds and method of use
US4189471A (en) * 1978-07-11 1980-02-19 Merck & Co., Inc. Immunologic glycolipid adjuvants

Also Published As

Publication number Publication date
CA1147722A (en) 1983-06-07
JPS5589298A (en) 1980-07-05
US4229441A (en) 1980-10-21
AU5300979A (en) 1980-06-05
EP0012083A1 (en) 1980-06-11

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