DK509579A - Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling - Google Patents

Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling

Info

Publication number
DK509579A
DK509579A DK509579A DK509579A DK509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A DK 509579 A DK509579 A DK 509579A
Authority
DK
Denmark
Prior art keywords
preparation
intermediates
glycolipid compounds
glycolipid
compounds
Prior art date
Application number
DK509579A
Other languages
English (en)
Inventor
R L Bugianesi
M M Ponpipom
T-Y Shen
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK509579A publication Critical patent/DK509579A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK509579A 1978-12-01 1979-11-30 Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling DK509579A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/965,559 US4229441A (en) 1978-12-01 1978-12-01 Immunologic adjuvant

Publications (1)

Publication Number Publication Date
DK509579A true DK509579A (da) 1980-06-02

Family

ID=25510144

Family Applications (1)

Application Number Title Priority Date Filing Date
DK509579A DK509579A (da) 1978-12-01 1979-11-30 Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling

Country Status (6)

Country Link
US (1) US4229441A (da)
EP (1) EP0012083A1 (da)
JP (1) JPS5589298A (da)
AU (1) AU5300979A (da)
CA (1) CA1147722A (da)
DK (1) DK509579A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259324A (en) * 1979-07-31 1981-03-31 Merck & Co., Inc. Immunologic adjuvant thio glycoside compounds and compositions
JPS59118053A (ja) * 1982-12-24 1984-07-07 Hayashibara Biochem Lab Inc 飲食物とその製造方法
DE3688364T2 (de) 1985-11-25 1993-11-25 Merck & Co Inc Steroidische Glycolipide als Immunstimulatoren.
US4652553A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators
US4652637A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids
EP0267297B1 (en) * 1986-05-12 1993-09-15 Mect Corporation Sialosylcholesterol, process for its preparation, and drug for treating diseases of nervous system
US4970199A (en) * 1987-06-18 1990-11-13 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US5019568A (en) * 1987-06-18 1991-05-28 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US4942154A (en) * 1987-06-18 1990-07-17 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
ATE147633T1 (de) * 1988-10-27 1997-02-15 Univ Minnesota Immunhilfsmittel aus liposome enthaltend lymphokin il -2
JPH04300891A (ja) * 1991-03-29 1992-10-23 Nisshin Oil Mills Ltd:The S−グリコシドを有するガングリオシド類縁体
US5514784A (en) * 1993-03-19 1996-05-07 Wong; Chi-Huey Thio linked glycosyl compounds
US5660855A (en) * 1995-02-10 1997-08-26 California Institute Of Technology Lipid constructs for targeting to vascular smooth muscle tissue
US5695738A (en) * 1995-06-15 1997-12-09 Glycomed Incorporated Steroidal C-glycosides
WO1998009650A1 (en) * 1996-09-06 1998-03-12 Mitsubishi Chemical Corporation Vaccinal preparations
JPH11199598A (ja) * 1998-01-08 1999-07-27 Yokohama Kokusai Bio Kenkyusho:Kk ウルソデオキシコール酸誘導体とその製造法
US6444649B1 (en) 1998-04-10 2002-09-03 Mitsubishi Chemical Corporation Solid dispersion containing sialic acid derivative
WO2004089969A2 (en) * 2003-04-02 2004-10-21 The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services Cholesterol-containing compounds and their use as immunogens against borrelia burgdorferi

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050517A (en) * 1955-06-22 1962-08-21 Burroughs Wellcome Co Purine 6-thio-glycosides
US3585186A (en) * 1969-01-31 1971-06-15 American Cyanamid Co Preparation of glycopyranosiduronides and glycopyranosides and products resulting therefrom
DE2052634A1 (de) * 1970-10-27 1972-05-04 Dr Karl Thomae GmbH, 7950 Biberach Neue durch einen Steroidrest substi tuierte Derivate der Acrylsäure und Ver fahren zu ihrer Herstellung
JPS5428830A (en) * 1977-08-09 1979-03-03 Ichirou Azuma Immunological treating agent of tumor containing glycolipid as effective component
US4096247A (en) * 1977-02-16 1978-06-20 Smithkline Corporation Gold thio glucopyranoside compounds and method of use
US4189471A (en) * 1978-07-11 1980-02-19 Merck & Co., Inc. Immunologic glycolipid adjuvants

Also Published As

Publication number Publication date
AU5300979A (en) 1980-06-05
EP0012083A1 (en) 1980-06-11
US4229441A (en) 1980-10-21
JPS5589298A (en) 1980-07-05
CA1147722A (en) 1983-06-07

Similar Documents

Publication Publication Date Title
DK509579A (da) Glycolipidforbindelser,deres fremstilling og anvendelse samt mellemprodukter til brug ved deres fremstilling
DK319480A (da) Muramylpeptidforbindelser samt deres fremstilling og anvendelse
BR7901893A (pt) Composicao compreendendo poliestireno,poliolefina e copolimeros em bloco
NO152785C (no) Mellomprodukter til bruk ved fremstilling av substituerte 2-(2-benzimidazoylyl)-pyridiner.
DK531780A (da) Braendt i hovedsagen ikke poroest keramisk legeme fremgangmaade til fremstilling deraf og svindfrik keramisk raamateriale til brug ved fremgangsmaaden
DK162443C (da) 1,3-diacyl-2-oxindol-forbindelser samt 1-acyl-2-oxindol-forbindelser til anvendelse som mellemprodukter ved deres fremstilling
NO803208L (no) Senke for anvendelse ved smiing.
DK155236C (da) Sigtemiddel til anvendelse ved bueskydning
DK253780A (da) Anordning ved moppehoveder
DK491079A (da) Strukturelt farvede tvaerbindelige forbindelser,deres fremstilling og deres anvendelse i overtraeksmidler
NO790934L (no) 2,6-dialkoksybenzamider og fremgangsmaate til deres fremstilling
DK295780A (da) Kufferthaandtag
DK465978A (da) Fremgangsmaade til fremstilling af deoxynarasinkomplexet samt kultur til brug ved fremgangsmaaden og foderstof indeholdende naevnte komplex
DK467780A (da) Fremgangsmaade til fremstilling af 24,24-difluor25-hydrochlecalciferol og mellemprodukter til brug ved fremgangsmaaden
DK184779A (da) Substituerede 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepiner fremgangsmaade til deres fremstilling samt deres anvendelse
DK287779A (da) Alkyl-n-trifluoracetyl-n-phosphonomethylycinat-forbindelser og deres anvendelse i herbicider
DK458579A (da) Substituerede n-propargylaniliner fremgangsmaade til deres fremstilling samt anvendelse heraf som fungicider
DK191679A (da) Substituerede alkanyl-azolyl-oximcarbamater samt fremgangsmaader til deres fremstilling og deres anvendelse som insecticider acaricider og nematodicider
DK419278A (da) Fremgangsmaade til fremstilling af 2,3-dihydrobenzofuranoler samt mellemprodukt til brug ved fremgangsmaaden
DK4679A (da) Carbamoyltriazolyl-o,n-acetaler deres fremstilling og anvendelse
DK534079A (da) Isoxazol-4-carboxylsyreamider deres fremstilling og anvendelse samt ved fremstillingen anvendte mellemprodukter
DK36479A (da) 2,6-dinitrobenzenaminer deres fremstilling og anvendelse
FI790944A7 (fi) Bryggfoerstaerkare
DK54179A (da) N-azolylalkyl-anillin samt fremgangsmaader til deres fremstilling
BR7901260A (pt) Cilindro travador