DK515580A - Fremgangsmaade til fremstilling af 11-ketosteroider - Google Patents

Fremgangsmaade til fremstilling af 11-ketosteroider

Info

Publication number
DK515580A
DK515580A DK515580A DK515580A DK515580A DK 515580 A DK515580 A DK 515580A DK 515580 A DK515580 A DK 515580A DK 515580 A DK515580 A DK 515580A DK 515580 A DK515580 A DK 515580A
Authority
DK
Denmark
Prior art keywords
ketosteroids
procedure
preparation
steroid
aprotic
Prior art date
Application number
DK515580A
Other languages
English (en)
Other versions
DK146097B (da
DK146097C (da
Inventor
P E Schulze
U Kerb
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK515580A publication Critical patent/DK515580A/da
Publication of DK146097B publication Critical patent/DK146097B/da
Application granted granted Critical
Publication of DK146097C publication Critical patent/DK146097C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK515580A 1979-12-10 1980-12-03 Fremgangsmaade til fremstilling af 11-ketosteroider eller 11-keto-d-homosteroider DK146097C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2950026 1979-12-10
DE2950026A DE2950026C2 (de) 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden

Publications (3)

Publication Number Publication Date
DK515580A true DK515580A (da) 1981-06-11
DK146097B DK146097B (da) 1983-06-27
DK146097C DK146097C (da) 1983-12-05

Family

ID=6088284

Family Applications (1)

Application Number Title Priority Date Filing Date
DK515580A DK146097C (da) 1979-12-10 1980-12-03 Fremgangsmaade til fremstilling af 11-ketosteroider eller 11-keto-d-homosteroider

Country Status (10)

Country Link
US (1) US4315866A (da)
EP (1) EP0030368B1 (da)
JP (1) JPS5692900A (da)
AT (1) ATE2534T1 (da)
CA (1) CA1141750A (da)
DE (2) DE2950026C2 (da)
DK (1) DK146097C (da)
HU (1) HU182250B (da)
IE (1) IE50611B1 (da)
IL (1) IL61601A (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
USRE35517E (en) * 1987-08-25 1997-05-20 University Of Southern California Method, compositions, and compounds for modulating brain excitability
US5120723A (en) * 1987-08-25 1992-06-09 University Of Southern California Method, compositions, and compounds for modulating brain excitability
FR2691968B1 (fr) * 1992-06-04 1994-07-29 Roussel Uclaf Nouveau procede de preparation d'un derive sterouide 11-ceto.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
DE2929558C2 (de) * 1979-07-18 1982-03-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden

Also Published As

Publication number Publication date
EP0030368A1 (de) 1981-06-17
DE2950026B1 (de) 1981-07-23
EP0030368B1 (de) 1983-02-16
IE50611B1 (en) 1986-05-28
DK146097B (da) 1983-06-27
DE3062082D1 (en) 1983-03-24
JPS6352640B2 (da) 1988-10-19
DE2950026C2 (de) 1982-05-19
JPS5692900A (en) 1981-07-27
DK146097C (da) 1983-12-05
US4315866A (en) 1982-02-16
HU182250B (en) 1983-12-28
ATE2534T1 (de) 1983-03-15
IL61601A (en) 1984-09-30
CA1141750A (en) 1983-02-22
IE802571L (en) 1981-06-10
IL61601A0 (en) 1981-01-30

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Legal Events

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PBP Patent lapsed