DK519486A - N-substituerede n-(3-(1,2,4-triazolo(4,3-b)pyridazin-6-yl)phenyl)alkanamider-carbamater og -urinstoffer, deres fremstilling og anvendelse - Google Patents

N-substituerede n-(3-(1,2,4-triazolo(4,3-b)pyridazin-6-yl)phenyl)alkanamider-carbamater og -urinstoffer, deres fremstilling og anvendelse

Info

Publication number
DK519486A
DK519486A DK519486A DK519486A DK519486A DK 519486 A DK519486 A DK 519486A DK 519486 A DK519486 A DK 519486A DK 519486 A DK519486 A DK 519486A DK 519486 A DK519486 A DK 519486A
Authority
DK
Denmark
Prior art keywords
urinents
alkanamides
pyridazin
triazolo
carbamates
Prior art date
Application number
DK519486A
Other languages
English (en)
Other versions
DK519486D0 (da
Inventor
Jay Donald Albright
Dennis William Powell
John Paul Dusza
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK519486D0 publication Critical patent/DK519486D0/da
Publication of DK519486A publication Critical patent/DK519486A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK519486A 1985-10-31 1986-10-30 N-substituerede n-(3-(1,2,4-triazolo(4,3-b)pyridazin-6-yl)phenyl)alkanamider-carbamater og -urinstoffer, deres fremstilling og anvendelse DK519486A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/793,437 US4654343A (en) 1985-10-31 1985-10-31 N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas

Publications (2)

Publication Number Publication Date
DK519486D0 DK519486D0 (da) 1986-10-30
DK519486A true DK519486A (da) 1987-05-01

Family

ID=25159919

Family Applications (1)

Application Number Title Priority Date Filing Date
DK519486A DK519486A (da) 1985-10-31 1986-10-30 N-substituerede n-(3-(1,2,4-triazolo(4,3-b)pyridazin-6-yl)phenyl)alkanamider-carbamater og -urinstoffer, deres fremstilling og anvendelse

Country Status (12)

Country Link
US (1) US4654343A (da)
EP (1) EP0223974A1 (da)
JP (1) JPS62108882A (da)
KR (1) KR900004833B1 (da)
AU (1) AU591940B2 (da)
DK (1) DK519486A (da)
ES (1) ES2002430A6 (da)
FI (1) FI864423A7 (da)
HU (1) HU196209B (da)
NO (1) NO165194C (da)
NZ (1) NZ218063A (da)
ZA (1) ZA868280B (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892873A (en) * 1985-10-31 1990-01-09 American Cyanamid Company N-substituted -N-(3-(1,2,4-triazolo-(4,3-b)pyridazin-6-yl)phenyl)alkanamides, carbamates and ureas
GB9507348D0 (en) * 1995-04-08 1995-05-31 Knoll Ag Therapeutic agents
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
WO2008109437A2 (en) * 2007-03-02 2008-09-12 Northwestern University Compositions and treatments for seizure-related disorders
GB9718254D0 (en) * 1997-08-28 1997-11-05 Merck Sharp & Dohme Therapeutic agents
US6297235B1 (en) * 1997-08-28 2001-10-02 Merck Sharp & Dohme Ltd. Triazolopyridazine derivatives for treating anxiety and enhancing cognition
GB9726701D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726699D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9726702D0 (en) * 1997-12-18 1998-02-18 Merck Sharp & Dohme Therapeutic use
GB9723999D0 (en) 1997-11-13 1998-01-14 Merck Sharp & Dohme Therapeutic use
US6110915A (en) * 1997-12-18 2000-08-29 Merck & Co., Inc. Antiemetic use of triazolo-pyridazine derivatives
AU746866B2 (en) * 1998-01-14 2002-05-02 Merck Sharp & Dohme Limited Triazolo-pyridazine derivatives as ligands for GABA receptors
GB9801208D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801210D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801234D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801202D0 (en) 1998-01-21 1998-03-18 Merck Sharp & Dohme Therapeutic agents
MXPA00007135A (es) * 1998-01-21 2002-11-07 Merck Sharp & Dohme Derivados de triazolo-piridazina como ligandos para receptores gaba.
GB9801397D0 (en) 1998-01-22 1998-03-18 Merck Sharp & Dohme Therapeutic agents
GB9801538D0 (en) * 1998-01-23 1998-03-25 Merck Sharp & Dohme Pharmaceutical product
TWI334868B (en) * 2003-06-03 2010-12-21 Nippon Kayaku Kk [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
KR100658771B1 (ko) * 2004-05-31 2006-12-15 고려대학교 산학협력단 고추 유래의 ＣａＯＤＣ1 유전자 도입 재조합 벡터 및이를 이용하여 형질전환된 식물병 저항성 향상 담배 변종식물체
ATE523199T1 (de) * 2004-11-02 2011-09-15 Univ Northwestern Pyridazinverbindungen und verfahren
BRPI0517947A (pt) 2004-11-02 2008-10-21 Univ Northwestern composto de piridazina, composições e métodos
TW200719895A (en) * 2005-05-26 2007-06-01 Wyeth Corp Method for the treatment of noise phobia in companion animals
JP2009535344A (ja) 2006-04-28 2009-10-01 ノースウェスタン ユニバーシティ 神経炎症性疾患の処置のためのピリダジン化合物を含む処方物
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
US20100168120A1 (en) * 2006-04-28 2010-07-01 Neuromedix Inc. Salts of pyridazine compounds
WO2009005675A1 (en) * 2007-06-28 2009-01-08 Abbott Laboratories Novel triazolopyridazines
HUE034911T2 (hu) * 2009-07-27 2018-03-28 Gilead Sciences Inc Fúzionált heterociklusos vegyületek mint ioncsatorna modulátorok
EP2588197B1 (en) 2010-07-02 2014-11-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
WO2012154760A1 (en) 2011-05-10 2012-11-15 Gilead Sciences, Inc. Fused heterocyclic compounds as sodium channel modulators
NO3175985T3 (da) 2011-07-01 2018-04-28
UY34171A (es) 2011-07-01 2013-01-31 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal iónico
CN115087657B (zh) * 2019-12-18 2025-01-21 加利福尼亚大学董事会 Lin28抑制剂和其使用方法
CN112225741B (zh) * 2020-12-09 2021-03-30 中山大学 1,2,4三唑并4,3-b哒嗪衍生物在制备抗炎症因子风暴药物中的应用
EP4598534A1 (en) * 2022-10-04 2025-08-13 ETH Zurich Compounds for the treatment of myotonic dystrophy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230705A (en) * 1976-09-22 1980-10-28 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety
CA1080712A (en) * 1976-09-22 1980-07-01 Jay D. Albright Hypotensive agents
US4112095A (en) * 1976-10-07 1978-09-05 American Cyanamid Company 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents
PH12424A (en) * 1976-10-26 1979-02-15 American Cyanamid Co Method of treating anxiety in mammals
US4260755A (en) * 1979-10-31 1981-04-07 American Cyanamid Company Novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines
DE3217325A1 (de) * 1982-05-08 1983-11-10 Hoechst Ag, 6230 Frankfurt 3-amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre herstellung und ihre verwendung
DE3311753A1 (de) * 1983-03-31 1984-10-04 Hoechst Ag, 6230 Frankfurt Substituierte 6-aryl-1,2,4-triazolo(4,3-b)pyridazine - ihre herstellung und verwendung -

Also Published As

Publication number Publication date
AU6454986A (en) 1987-05-07
FI864423A0 (fi) 1986-10-30
EP0223974A1 (en) 1987-06-03
NO864336D0 (no) 1986-10-30
US4654343A (en) 1987-03-31
NO864336L (no) 1987-05-04
NZ218063A (en) 1990-03-27
FI864423A7 (fi) 1987-05-01
ZA868280B (en) 1987-06-24
JPS62108882A (ja) 1987-05-20
KR870004034A (ko) 1987-05-07
HU196209B (en) 1988-10-28
KR900004833B1 (ko) 1990-07-07
ES2002430A6 (es) 1988-08-01
NO165194C (no) 1991-01-09
DK519486D0 (da) 1986-10-30
NO165194B (no) 1990-10-01
HUT43609A (en) 1987-11-30
AU591940B2 (en) 1989-12-21

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