DK522578A - G prostacyklinderivater og fremgangsmaade til deres fremstillin - Google Patents

G prostacyklinderivater og fremgangsmaade til deres fremstillin

Info

Publication number: DK522578A
Authority: DK; Denmark
Prior art keywords: procedure; preparation; prostacyclin derivatives; prostacyclin; derivatives
Prior art date: 1977-11-25

Application number

DK522578A

Other languages

English (en)

Other versions

DK153482C (da

DK153482B (da

Inventor

H Vorbrueggen

W Skuballa

B Raduechel

W Losert

O Loge

B Mueller

G Mannensmann

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-25

Filing date

1978-11-23

Publication date

1979-05-26

1978-11-23 Application filed by Schering Ag filed Critical Schering Ag

1979-05-26 Publication of DK522578A publication Critical patent/DK522578A/da

1988-07-18 Publication of DK153482B publication Critical patent/DK153482B/da

1988-12-27 Application granted granted Critical

1988-12-27 Publication of DK153482C publication Critical patent/DK153482C/da

Links

KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical class O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)

DK522578A 1977-11-25 1978-11-23 Analogifremgangsmaade til fremstilling af 5-cyano-prostacyklinderivater DK153482C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19772753244 DE2753244A1 (de)	1977-11-25	1977-11-25	Neue prostacyclinderivate und verfahren zu ihrer herstellung
DE2753244		1977-11-25

Publications (3)

Publication Number	Publication Date
DK522578A true DK522578A (da)	1979-05-26
DK153482B DK153482B (da)	1988-07-18
DK153482C DK153482C (da)	1988-12-27

Family

ID=6024901

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK522578A DK153482C (da)	1977-11-25	1978-11-23	Analogifremgangsmaade til fremstilling af 5-cyano-prostacyklinderivater

Country Status (23)

Country	Link
US (1)	US4219479A (da)
EP (1)	EP0002234B1 (da)
JP (1)	JPS5481257A (da)
AT (1)	AT371455B (da)
AU (1)	AU523420B2 (da)
CA (1)	CA1180701A (da)
CS (1)	CS209909B2 (da)
DD (1)	DD140042A5 (da)
DE (2)	DE2753244A1 (da)
DK (1)	DK153482C (da)
ES (1)	ES475377A1 (da)
FI (1)	FI68621C (da)
GR (1)	GR72772B (da)
HU (1)	HU181518B (da)
IE (1)	IE47497B1 (da)
IL (1)	IL56017A (da)
IT (1)	IT1160264B (da)
NO (1)	NO148642C (da)
NZ (1)	NZ188976A (da)
PH (1)	PH20276A (da)
SU (1)	SU923365A3 (da)
YU (1)	YU271078A (da)
ZA (1)	ZA786622B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4178367A (en) *	1977-02-21	1979-12-11	Ono Pharmaceutical Co. Ltd.	Prostaglandin I2 analogues
DE2902809A1 (de) *	1979-01-25	1980-08-07	Hoechst Ag	Neue analoga von prostacyclin
DE3004795A1 (de) *	1980-02-07	1981-08-13	Schering Ag Berlin Und Bergkamen, 1000 Berlin	Neue prostacyclinderivate, ihre herstellung und anwendung
DE3041601A1 (de) *	1980-10-31	1982-06-16	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3041602A1 (de) *	1980-10-31	1982-06-16	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue 5-cyan-prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3322893A1 (de) *	1983-06-23	1985-01-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3448257C2 (en) *	1984-07-25	1988-08-18	Schering Ag, 1000 Berlin Und 4709 Bergkamen, De	Cytoprotective action of prostacyclin derivatives on the kidney
DE3448256C2 (en) *	1984-07-25	1988-08-18	Schering Ag, 1000 Berlin Und 4709 Bergkamen, De	Cytoprotective action of prostacyclin derivatives on the pancreas
DE3740838A1 (de) *	1987-11-27	1989-06-08	Schering Ag	Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
JP2009543826A (ja) *	2006-07-18	2009-12-10	バイエル・シエーリング・ファーマアクチエンゲゼルシャフト	自己免疫疾患治療剤としての５−シアノ−プロスタサイクリン誘導体
EP2269611B1 (en) *	2006-11-16	2016-03-23	Gemmus Pharma Inc.	EP2 and EP4 agonists as agents for the treatment of influenza A viral infection
EP1975163A1 (en) *	2007-03-28	2008-10-01	Bayer Schering Pharma Aktiengesellschaft	Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of influenza a viral infection
US20080242713A1 (en) *	2007-03-28	2008-10-02	Bayer Schering Pharma Aktiengesellschaft	Novel 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases
US7776896B2 (en) *	2007-03-28	2010-08-17	Bayer Schering Pharma Aktiengesellschaft	5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection
EP1988087A1 (en) *	2007-03-28	2008-11-05	Bayer Schering Pharma Aktiengesellschaft	Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of autoimmune diseases
CA2920856C (en)	2013-08-09	2026-03-03	Ardelyx, Inc.	Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
CA3110469A1 (en)	2018-08-22	2020-02-27	Respira Technologies, Inc.	Electronic device for producing an aerosol for inhalation by a person
US12501929B2 (en)	2018-08-22	2025-12-23	Qnovia, Inc.	Electronic device for producing an aerosol for inhalation by a person
JP2022533251A (ja)	2019-05-21	2022-07-21	アルデリックス，インコーポレイテッド	患者において血清リン酸塩を低下させるための組み合わせ
US20210113783A1 (en)	2019-10-20	2021-04-22	Respira Technologies, Inc.	Electronic devices and liquids for aerosolizing and inhaling therewith
US12471625B2 (en)	2020-11-01	2025-11-18	Qnovia, Inc.	Electronic devices and liquids for aerosolizing and inhaling therewith
CA3261770A1 (en)	2022-04-22	2023-10-26	Qnovia, Inc.	ELECTRONIC DEVICES FOR VAPORIZING AND INHALATING LIQUID

1977
- 1977-11-25 DE DE19772753244 patent/DE2753244A1/de not_active Withdrawn
1978
- 1978-11-21 YU YU02710/78A patent/YU271078A/xx unknown
- 1978-11-22 IL IL56017A patent/IL56017A/xx unknown
- 1978-11-22 PH PH21832A patent/PH20276A/en unknown
- 1978-11-22 JP JP14358878A patent/JPS5481257A/ja active Granted
- 1978-11-22 NZ NZ188976A patent/NZ188976A/xx unknown
- 1978-11-23 DK DK522578A patent/DK153482C/da active
- 1978-11-23 DE DE7878101445T patent/DE2860486D1/de not_active Expired
- 1978-11-23 AT AT0836478A patent/AT371455B/de not_active IP Right Cessation
- 1978-11-23 EP EP78101445A patent/EP0002234B1/de not_active Expired
- 1978-11-23 FI FI783590A patent/FI68621C/fi not_active IP Right Cessation
- 1978-11-23 GR GR57720A patent/GR72772B/el unknown
- 1978-11-24 HU HU78SCHE661A patent/HU181518B/hu not_active IP Right Cessation
- 1978-11-24 IT IT30174/78A patent/IT1160264B/it active
- 1978-11-24 CA CA000316872A patent/CA1180701A/en not_active Expired
- 1978-11-24 ZA ZA00786622A patent/ZA786622B/xx unknown
- 1978-11-24 SU SU782690452A patent/SU923365A3/ru active
- 1978-11-24 NO NO783964A patent/NO148642C/no unknown
- 1978-11-24 US US05/963,240 patent/US4219479A/en not_active Expired - Lifetime
- 1978-11-24 AU AU41912/78A patent/AU523420B2/en not_active Expired
- 1978-11-24 CS CS787724A patent/CS209909B2/cs unknown
- 1978-11-24 ES ES475377A patent/ES475377A1/es not_active Expired
- 1978-11-24 IE IE2321/78A patent/IE47497B1/en not_active IP Right Cessation
- 1978-11-27 DD DD78209338A patent/DD140042A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ188976A (en)	1979-12-11
ES475377A1 (es)	1979-04-01
AU523420B2 (en)	1982-07-29
HU181518B (en)	1983-10-28
SU923365A3 (ru)	1982-04-23
IE782321L (en)	1979-05-25
AU4191278A (en)	1979-05-31
IL56017A0 (en)	1979-01-31
DE2860486D1 (en)	1981-03-26
IT1160264B (it)	1987-03-11
IL56017A (en)	1983-03-31
FI783590A7 (fi)	1979-05-26
IT7830174A0 (it)	1978-11-24
JPS6220989B2 (da)	1987-05-11
YU271078A (en)	1983-01-21
PH20276A (en)	1986-11-14
EP0002234B1 (de)	1981-02-11
FI68621C (fi)	1985-10-10
JPS5481257A (en)	1979-06-28
AT371455B (de)	1983-06-27
NO148642C (no)	1983-11-16
NO783964L (no)	1979-05-28
ATA836478A (de)	1982-11-15
EP0002234A1 (de)	1979-06-13
US4219479A (en)	1980-08-26
DD140042A5 (de)	1980-02-06
ZA786622B (en)	1979-10-31
CA1180701A (en)	1985-01-08
DK153482C (da)	1988-12-27
DK153482B (da)	1988-07-18
CS209909B2 (en)	1981-12-31
IE47497B1 (en)	1984-04-04
DE2753244A1 (de)	1979-06-07
FI68621B (fi)	1985-06-28
NO148642B (no)	1983-08-08
GR72772B (da)	1983-12-05

Publication	Publication Date	Title
NO781130L (no)	1978-10-03	Cephemderivater og fremgangsmaate til deres fremstilling
DK92378A (da)	1978-09-04	Substituerede phenoxybenzyloxycarbonylderivater fremgangsmaade til deres femstilling og deres anvendelse som insecticider og acaricider
DK495476A (da)	1977-05-07	Phenolethere og fremgangsmade til deres fremstilling
DK173778A (da)	1978-10-22	Fremgangsmaade til fremstilling af mercaptoalkylsulfonylprolinderivater og dermed beslaegtede forbindelser
NO783471L (no)	1979-04-18	Xantinderivater og fremgangsmaate til deres fremstilling
DK557876A (da)	1977-06-13	Polyhalogensteroider og fremgangsmade til deres fremstilling
DK180878A (da)	1978-11-17	Fremgangsmaade til fremstilling af imidazoaziner og imidazodiaziner
DK445078A (da)	1979-04-08	Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf
DK495578A (da)	1979-05-09	Quinazolderivater og fremgangsmaade til fremstilling deraf
DK313878A (da)	1979-01-14	Indolderivater og fremgangsmaade til fremstilling deraf
DK150778A (da)	1978-10-06	Prostanderivater og fremgangsmaade til fremstilling heraf
NO780800L (no)	1978-09-12	Azoforbindelser og fremgangsmaate til deres fremstilling
DK582578A (da)	1979-06-30	2,4-thiazolidindion-derivater og fremgangsmaade til deres fremstilling
DK308878A (da)	1979-02-19	Aminoglyosidderivater og fremgangsmaader til deres fremstilling
DK31576A (da)	1976-09-19	Acetylenderivater og fremgangsmade til deres fremstilling
DK111678A (da)	1978-09-15	Enzym-marumer og fremgangsmaade til deres fremstilling
DK416278A (da)	1979-03-23	2-oxazolidon-derivater og fremgangsmaade til deres fremstilling
DK323378A (da)	1979-01-22	Imidazo-isoquinolin-dioner og fremgangsmaade til deres fremstilling
DK161377A (da)	1977-10-14	Naphtyridinderivater og fremgangsmade til deres fremstilling
DK458977A (da)	1978-10-01	Fremgangsmaade til fremstilling af maytansinol og derivater deraf
DK574978A (da)	1979-06-23	Fremgangsmaade til fremstilling af polyfluorhydroxyisopropylderivater af cicycliske og tricycliske carbostyriler
DK341576A (da)	1977-01-31	Homophthalimider og fremgangsmade til deres fremstilling
DK21579A (da)	1979-07-21	5-phenethyl-2-oxazolidon-derivater og fremgangsmaade til deres fremstilling
DK334079A (da)	1980-02-11	Anthraquinon-derivater og fremgangsmaade til deres fremstilling
DK24280A (da)	1980-07-23	Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse