DK524788A - Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstande - Google Patents
Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstandeInfo
- Publication number
- DK524788A DK524788A DK524788A DK524788A DK524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A DK 524788 A DK524788 A DK 524788A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- treatment
- acquired
- immundefect
- conditions
- Prior art date
Links
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 title abstract 4
- 239000005557 antagonist Substances 0.000 title abstract 2
- 229960005181 morphine Drugs 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
- 208000029483 Acquired immunodeficiency Diseases 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 230000002584 immunomodulator Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 abstract 1
- 229960003086 naltrexone Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/34—Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/35—Corticotropin [ACTH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8700670A FR2609632B1 (fr) | 1987-01-21 | 1987-01-21 | Nouvelle application therapeutique de la 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinon-6-one et les compositions pharmaceutiques destinees a cet usage |
| PCT/FR1988/000032 WO1988005297A1 (fr) | 1987-01-21 | 1988-01-21 | Utilisation d'antagonistes de la morphine dans la preparation de medicaments a effet immunomodulateur et anti-viral, destines notamment a traiter les etats immuno-deficitaires acquis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK524788D0 DK524788D0 (da) | 1988-09-21 |
| DK524788A true DK524788A (da) | 1988-11-18 |
Family
ID=9347124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK524788A DK524788A (da) | 1987-01-21 | 1988-09-21 | Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstande |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0278821B1 (da) |
| JP (1) | JPH02502278A (da) |
| AT (1) | ATE112488T1 (da) |
| AU (1) | AU610561B2 (da) |
| DE (1) | DE3851711D1 (da) |
| DK (1) | DK524788A (da) |
| FR (1) | FR2609632B1 (da) |
| OA (1) | OA09124A (da) |
| WO (1) | WO1988005297A1 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5095035A (en) * | 1981-07-31 | 1992-03-10 | Eby Iii George A | Flavor stable zinc acetate compositions for oral absorption |
| US4877791A (en) * | 1988-11-01 | 1989-10-31 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for interestitial cystitis |
| US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
| RU2058553C1 (ru) * | 1994-03-18 | 1996-04-20 | Иван Николаевич Головистиков | Способ определения супрессорного звена иммунного статуса человека |
| RU2056852C1 (ru) * | 1994-03-18 | 1996-03-27 | Иван Николаевич Головистиков | Средство для лечения аутоиммунных заболеваний с иммунодефицитом супрессоров и способ лечения аутоиммунных заболеваний |
| US6274591B1 (en) | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
| ATE510534T1 (de) * | 2002-03-14 | 2011-06-15 | Euro Celtique Sa | Naltrexonhydrochlorid-zusammensetzungen |
| RU2224518C1 (ru) * | 2003-02-10 | 2004-02-27 | Дулькис Мария Дмитриевна | Жидкая лекарственная форма налтрексона |
| HRP20150037T4 (hr) | 2003-04-08 | 2022-09-02 | Progenics Pharmaceuticals, Inc. | Farmaceutske formulacije koje sadrže metilnaltrekson |
| RU2238093C1 (ru) * | 2003-08-07 | 2004-10-20 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Фторированные производные 2-ароил-3-метил-6,7-дифторбенз[4,5]-имидазо[1,2-b][1,3]-тиазолов-ингибитор ы репродукции вируса кори |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| ES2714198T3 (es) | 2005-03-07 | 2019-05-27 | Univ Chicago | Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| SI2565195T1 (sl) | 2007-03-29 | 2015-09-30 | Wyeth Llc | Periferalni opioidni receptorji in antagonisti in njih uporaba |
| CL2008000905A1 (es) | 2007-03-29 | 2008-08-22 | Progenics Pharm Inc | Compuestos derivados de morfina, antagonistas del receptor opioide periferico; metodo de preparacion; composicion farmaceutica; y uso para reducir los efectos de la actividad opioide endogena. |
| MX2009010550A (es) | 2007-03-29 | 2009-12-14 | Progenics Pharm Inc | Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas. |
| EP2240489A1 (en) | 2008-02-06 | 2010-10-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| EP2278966B1 (en) | 2008-03-21 | 2019-10-09 | The University of Chicago | Treatment with opioid antagonists and mtor inhibitors |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| EP3939570A1 (en) * | 2016-02-18 | 2022-01-19 | Immune Therapeutics, Inc. | Naltrexone for treating or preventing autoimmune and inflammatory diseases |
| US11285192B2 (en) | 2019-03-13 | 2022-03-29 | Adamis Pharmaceuticals Corporation | Formulation including a combination of beta-endorphin and adrenocorticotropic hormone |
| SG11202109652TA (en) * | 2019-03-13 | 2021-10-28 | Adamis Pharmaceuticals Corp | FORMULATION INCLUDING A COMBINATION OF ß-ENDORPHIN AND ADRENOCORTICOTROPIC HORMONE |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3332950A (en) * | 1963-03-23 | 1967-07-25 | Endo Lab | 14-hydroxydihydronormorphinone derivatives |
-
1987
- 1987-01-21 FR FR8700670A patent/FR2609632B1/fr not_active Expired - Lifetime
-
1988
- 1988-01-21 WO PCT/FR1988/000032 patent/WO1988005297A1/fr not_active Ceased
- 1988-01-21 AT AT88400132T patent/ATE112488T1/de not_active IP Right Cessation
- 1988-01-21 JP JP87506276A patent/JPH02502278A/ja active Pending
- 1988-01-21 AU AU11896/88A patent/AU610561B2/en not_active Ceased
- 1988-01-21 DE DE3851711T patent/DE3851711D1/de not_active Expired - Lifetime
- 1988-01-21 EP EP88400132A patent/EP0278821B1/fr not_active Expired - Lifetime
- 1988-09-21 DK DK524788A patent/DK524788A/da not_active Application Discontinuation
-
1989
- 1989-07-20 OA OA59616A patent/OA09124A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3851711D1 (de) | 1994-11-10 |
| AU1189688A (en) | 1988-08-10 |
| OA09124A (fr) | 1991-10-31 |
| FR2609632A1 (fr) | 1988-07-22 |
| EP0278821B1 (fr) | 1994-10-05 |
| EP0278821A1 (fr) | 1988-08-17 |
| DK524788D0 (da) | 1988-09-21 |
| FR2609632B1 (fr) | 1991-03-29 |
| AU610561B2 (en) | 1991-05-23 |
| WO1988005297A1 (fr) | 1988-07-28 |
| JPH02502278A (ja) | 1990-07-26 |
| ATE112488T1 (de) | 1994-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK524788D0 (da) | Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstande | |
| DK0509019T3 (da) | Behandling af humane retrovirale infektioner med 2',3'-dideoxyinosin | |
| DK162965C (da) | Anvendelse af et difluornucleosid eller et farmaceutisk acceptabelt salt deraf til fremstilling af et laegemiddel til behandling af neoplasma | |
| ES2149267T3 (es) | Carbonilos ciclicos substituidos y derivados de los mismos utiles como inhibidores de la proteasa retroviral. | |
| ES2130114T3 (es) | 5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepinas y su uso en la prevencion o tratamiento de infeccion por hiv. | |
| DK602988D0 (da) | Nukleosidderivater med antiviral virkning og laegemiddelpraeparat indeholdende saadanne forbindelser | |
| DK336688D0 (da) | Nucleosider od fremgangsmaade til fremstilling deraf | |
| ZA913033B (en) | N-(3-fluoro-2-phosphonylmethoxypropyl)derivatives of purine and pyrimidine heterocyclic basis,their preparation and use | |
| DK92788A (da) | Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retrovira | |
| DK422589D0 (da) | Farmaceutisk praeparat til behandling af immundefekttilstande | |
| DK557087A (da) | Forbindelse til behandling af retrovirusinfektioner | |
| DK538888A (da) | Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat | |
| ATE132163T1 (de) | Neue polypeptide und damit hergestellte anti-hiv medikamente | |
| TW371662B (en) | Antiviral acyclic phosphonomethoxyalkyl substituted alkenyl purine and pyrimidine derivatives | |
| DE3788338D1 (de) | Vorbehandlungswirkstoff zur perkutanen verabreichung. | |
| IT8621397A0 (it) | Derivati del pirrolidin-2-one adattivita' nootropa. | |
| ATE108335T1 (de) | Kit oder zusammensetzung zur vorbeugung oder behandlung von hiv-1 infektionen. | |
| IT1225262B (it) | Metodo per la sensibilizzazione di piccoli animali all'infezione da virus dell'immunodeficienza umana (hiv) | |
| ES2066897T3 (es) | 5,11-dihidro-6h-pirido(2,3-b)(1,4)benzodiazepin-6-onas y -tionas y su uso en la prevencion o el tratamiento del sida. | |
| DK469487A (da) | Laegemiddel til behandling af fedme | |
| FI862412L (fi) | Anordning foer omraodet av draget med enkel vira i flercylindertorken av en pappersmaskin. | |
| ATE79529T1 (de) | Vorrichtung zur stimulation von gliedversteifungen. | |
| DE69010736D1 (de) | Anti-HIV Zusammensetzungen. | |
| IT8720402A0 (it) | Procedimento per la preparazione di derivati condensati as-triazinici. | |
| IT8723272A0 (it) | Derivati pirimidinici condensati e procedimento per la loro preparazione. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |