DK527789A - Dithiocarbamoylquinoloner og sammensaetninger omfattende samme - Google Patents

Dithiocarbamoylquinoloner og sammensaetninger omfattende samme

Info

Publication number
DK527789A
DK527789A DK527789A DK527789A DK527789A DK 527789 A DK527789 A DK 527789A DK 527789 A DK527789 A DK 527789A DK 527789 A DK527789 A DK 527789A DK 527789 A DK527789 A DK 527789A
Authority
DK
Denmark
Prior art keywords
dithiocarbamoylquinolons
comprehensive same
compositions
compositions comprehensive
same
Prior art date
Application number
DK527789A
Other languages
Danish (da)
English (en)
Other versions
DK527789D0 (da
Inventor
Jr Thomas Prosser Demuth
Ronald Eugene White
Original Assignee
Norwich Eaton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Eaton Pharma filed Critical Norwich Eaton Pharma
Publication of DK527789D0 publication Critical patent/DK527789D0/da
Publication of DK527789A publication Critical patent/DK527789A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK527789A 1988-10-24 1989-10-24 Dithiocarbamoylquinoloner og sammensaetninger omfattende samme DK527789A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26194888A 1988-10-24 1988-10-24
US41802989A 1989-10-12 1989-10-12

Publications (2)

Publication Number Publication Date
DK527789D0 DK527789D0 (da) 1989-10-24
DK527789A true DK527789A (da) 1990-04-25

Family

ID=26948929

Family Applications (1)

Application Number Title Priority Date Filing Date
DK527789A DK527789A (da) 1988-10-24 1989-10-24 Dithiocarbamoylquinoloner og sammensaetninger omfattende samme

Country Status (10)

Country Link
US (2) US5387748A (fr)
EP (1) EP0366643A3 (fr)
JP (1) JP2875015B2 (fr)
KR (1) KR900006333A (fr)
AU (1) AU631379B2 (fr)
CA (1) CA2001203C (fr)
DK (1) DK527789A (fr)
NZ (1) NZ231111A (fr)
PH (1) PH29981A (fr)
WO (1) WO1990004591A1 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
CA2001203C (fr) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Dithiocarbamoyl quinolones antimicrobiens
EP0366640B1 (fr) * 1988-10-24 1999-02-03 Procter & Gamble Pharmaceuticals, Inc. Fluoroquinolonyl céphems antimicrobiens
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
EP0366189A3 (fr) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Lactames-quinolones antimicrobiennes
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
KR100204987B1 (ko) * 1990-04-18 1999-06-15 제이코버스 코넬리스 레이서 항미생물성 퀴놀로닐 락탐
KR950005301B1 (ko) * 1990-09-04 1995-05-23 주식회사대웅제약 신규한 퀴놀론 카르복실산 유도체
WO1994025464A1 (fr) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Nouveaux derives d'acide quinolone-carboxylique et leur procede de preparation
WO1995006637A1 (fr) * 1993-09-03 1995-03-09 Smithkline Beecham Plc Nouveaux derives d'indole et d'indoline en tant qu'antagonistes du recepteur de 5ht1d
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
CA2265877A1 (fr) * 1996-09-10 1998-03-19 Medinox, Inc. Macromolecules contenant du polydithiocarbamate, et leur utilisation dans des applications therapeutiques et diagnostiques
DE19652239A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
DE69840599D1 (de) 1997-09-15 2009-04-09 Procter & Gamble Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
BR0212864A (pt) 2001-09-26 2004-08-17 Bayer Pharmaceuticals Corp Derivados de 1,6-naftiridina como antidiabéticos
KR20060069836A (ko) * 2003-08-12 2006-06-22 아칠리온 파르마세우티칼스 인코포레이티드 항-감염제로서의 이소티아졸로퀴놀론 및 관련 화합물
AU2005273961A1 (en) * 2004-08-11 2006-02-23 Williamsburg Holdings Llc Noncardiotoxic pharmaceutical compounds
KR101289115B1 (ko) * 2004-08-13 2013-07-23 엠에스디 인터내셔널 홀딩즈 게엠베하 항생제인 트리아졸 및 코르티코스테로이드를 포함하는약제학적 제형
CN101120004A (zh) * 2004-11-11 2008-02-06 艾其林医药公司 用作抗感染剂的8a,9-二氢-4a-h-异噻唑[5,4-b]喹啉-3,4-二酮及相关化合物
US7659399B2 (en) * 2005-01-05 2010-02-09 Achillion Pharmaceuticals, Inc. 1-thia-2,4a-diaza-cyclopenta[b]napththalene-3,4-diones and related compounds as anti-infective agents
WO2006084053A1 (fr) * 2005-02-02 2006-08-10 Achillion Pharmaceuticals, Inc. 2h-isothiazolo[5,4-b]quinolizine-3,4-diones 8-n-substituees et composes relatifs servant d'agents anti-infectieux
ATE491713T1 (de) * 2005-02-16 2011-01-15 Achillion Pharmaceuticals Inc Neue isothiazolochinolone und verwandte verbindungen als infektionsschutzmittel
JP5143000B2 (ja) 2005-07-27 2013-02-13 アキリオン ファーマシューティカルズ，インコーポレーテッド 抗感染症薬としての８−メトキシ−９Ｈ−イソチアゾロ［５，４−ｂ］キノリン−３，４−ジオンおよび関連化合物
AU2007225088B2 (en) * 2006-03-13 2012-09-13 Kyorin Pharmaceutical Co., Ltd Aminoquinolones as GSK-3 inhibitors
US7456279B2 (en) * 2006-03-28 2008-11-25 The Procter & Gamble Company Coupling process for preparing quinolone intermediates
SMP200800058B (it) * 2006-03-28 2009-09-07 Procter & Gamble Sali e polimorfi malati di un acido (3s, 5s) -7- [3-ammino-5-metilpiperidinil]-1-ciclopropil-1,4-diidro-8-metossi-4-osso-3-chinolincarbossilico
WO2009035634A2 (fr) * 2007-09-11 2009-03-19 Activx Biosciences, Inc. Cyanoaminoquinolones et tétrazoloaminoquinolones en tant qu'inhibiteurs de gsk-3
CN102344457B (zh) 2007-09-12 2015-07-22 杏林制药株式会社 作为 gsk-3 抑制剂的螺环状氨基喹诺酮
BRPI1008974A2 (pt) * 2009-03-11 2017-06-06 Kyorin Seiyaku Kk composto, composição farmacêutica, e, método para tratar, prevenir ou melhorar uma doença mediada com gsk-3
EA201101451A1 (ru) * 2009-04-03 2012-03-30 Ачиллион Фармасьютикалз, Инк. Гидрокситиенохинолоны и родственные соединения как противоинфекционные средства

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33873B (en) * 1968-08-08 1978-06-30 Pliva Pharm & Chem Works Process for the preparation of the novel 6-nalidixyl-penicillanic acid
JPS5219561Y2 (fr) * 1971-03-05 1977-05-06
AR204813A1 (es) * 1972-05-08 1976-03-05 Yamanouchi Pharma Co Ltd Proceso para la preparacion de derivados de ampilicina
FR2191556A5 (en) * 1972-06-29 1974-02-01 Aries Robert N-Acylampicillins - with broad-spectrum antibacterial activity prepd. by acylation with naphthyridine carboxylic acids
JPS4935392A (fr) * 1972-08-02 1974-04-01
JPS5023037A (fr) * 1973-07-03 1975-03-12
JPS5023036A (fr) * 1973-07-06 1975-03-12
FR2243940A1 (en) * 1973-09-17 1975-04-11 Aries Robert Antibacterial nalidixamido cephems - prepd from 7-amino cephem (salt) and nalidixic acid deriv
US3939150A (en) * 1973-10-19 1976-02-17 Yamanouchi Pharmaceutical Co., Ltd. Penicillin derivatives
GB1509074A (en) * 1974-04-05 1978-04-26 Yamanouchi Pharma Co Ltd Cephalosporin derivatives
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
JPS5573686A (en) * 1978-11-28 1980-06-03 Mitsui Toatsu Chem Inc Novel penicillin
JPS5732290A (en) * 1980-08-06 1982-02-20 Fujimoto Seiyaku Kk Novel penicillin derivative and its preparation
JPS5746988A (en) * 1980-09-03 1982-03-17 Fujimoto Seiyaku Kk Novel penicillin derivative and its preparation
JPS5746990A (en) * 1980-09-03 1982-03-17 Fujimoto Seiyaku Kk Novel cephalexin derivative and its preparation
US4620007A (en) * 1980-09-03 1986-10-28 Bayer Aktiengesellschaft 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
WO1982001873A1 (fr) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd Derives 1-sulfo-2-oxoazetidine et leur procede de preparation
US4468394A (en) * 1981-04-02 1984-08-28 Eisai Co., Ltd. Cephalosporin compounds
JPS57202170A (en) * 1981-06-08 1982-12-10 Nippon Telegr & Teleph Corp <Ntt> Line selecting system
US4546176A (en) * 1982-12-14 1985-10-08 Eisai Co., Ltd. 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same
JPS606617A (ja) * 1983-05-09 1985-01-14 Kyorin Pharmaceut Co Ltd 抗菌性組成物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
EP0182210B1 (fr) * 1984-11-12 1991-02-27 Banyu Pharmaceutical Co., Ltd. Dérivés de céphalosporine
EP0191185B1 (fr) * 1984-12-14 1990-03-07 Daiichi Seiyaku Co., Ltd. Dérivés de l'acide quinoléine-carboxylique
IT1215277B (it) * 1985-05-27 1990-01-31 Pomezia Roma A Derivato chinolin-lattaminico ad attivita' antibatterica ed inibitrice delle b-lattamasi.
DE3525108A1 (de) * 1985-06-07 1986-12-11 Bayer Ag, 5090 Leverkusen Antibakteriell wirksame chinoloncarbonsaeureester
DE3683922D1 (de) * 1985-09-24 1992-03-26 Hoffmann La Roche Chinolinderivate.
GB8626245D0 (en) * 1985-11-27 1986-12-03 Ici Pharma Cephalosporin compounds
DE3542002A1 (de) * 1985-11-28 1987-06-04 Bayer Ag 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
DE3606698A1 (de) * 1986-03-01 1987-09-03 Bayer Ag 7-(1-pyrrolidinyl)-chinoloncarbonsaeure -derivate
US4783443A (en) * 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
JPS62274855A (ja) * 1986-05-22 1987-11-28 Nec Corp 中継交換機の経路選択方式
JPS62274965A (ja) * 1986-05-23 1987-11-28 Nec Corp ル−ト選択スケジユ−リング方法
ZA874696B (en) * 1986-07-03 1988-01-04 F. Hoffmann-La Roche & Co. Aktiengesellschaft Acyl derivatives
NZ222047A (en) * 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
US4954507A (en) * 1986-10-08 1990-09-04 Bristol-Myers Company 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents
HU200917B (en) * 1987-07-20 1990-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical compositions comprising quinoline or naphthyridinecarboxylic acid and tetracycline derivatives as active ingredient
ATE130299T1 (de) * 1987-07-23 1995-12-15 Zeneca Pharma Sa Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate.
GB8816519D0 (en) * 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
US4803205A (en) * 1987-08-07 1989-02-07 Warner-Lambert Company Quinolones as antibacterial agents
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
NZ227470A (en) * 1987-12-28 1991-06-25 Hoffmann La Roche Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
YU63689A (en) * 1988-03-31 1991-06-30 Hoffmann La Roche Acyl derivatives
JPH01258684A (ja) * 1988-04-07 1989-10-16 Banyu Pharmaceut Co Ltd ３‐置換キノリニウムチオメチルセファロスポリン誘導体
ATE113953T1 (de) * 1988-05-10 1994-11-15 Ici Plc Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate.
CA2001203C (fr) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Dithiocarbamoyl quinolones antimicrobiens
EP0366640B1 (fr) * 1988-10-24 1999-02-03 Procter &amp; Gamble Pharmaceuticals, Inc. Fluoroquinolonyl céphems antimicrobiens
EP0366189A3 (fr) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Lactames-quinolones antimicrobiennes
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
EP0366193A3 (fr) * 1988-10-24 1992-01-08 Norwich Eaton Pharmaceuticals, Inc. Quinolonyl-lactames antimicrobiennes
DE68929227T2 (de) * 1988-10-24 2001-05-31 Procter & Gamble Pharmaceuticals, Inc. Antimikrobielle Quinolonyllactamester
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
KR100204987B1 (ko) * 1990-04-18 1999-06-15 제이코버스 코넬리스 레이서 항미생물성 퀴놀로닐 락탐
US5066800A (en) * 1990-04-27 1991-11-19 Hoffmann-La Roche Inc. Qunoline intermediates useful therein for synthesizing antibacterial compounds
US5112967A (en) * 1990-04-27 1992-05-12 Hoffmann-La Roches Inc. Process for synthesizing antibacterial cephalosporin compounds

Also Published As

Publication number Publication date
DK527789D0 (da) 1989-10-24
CA2001203C (fr) 2001-02-13
US5672600A (en) 1997-09-30
JPH03503533A (ja) 1991-08-08
KR900006333A (ko) 1990-05-07
WO1990004591A1 (fr) 1990-05-03
EP0366643A3 (fr) 1991-12-04
PH29981A (en) 1996-10-29
EP0366643A2 (fr) 1990-05-02
AU631379B2 (en) 1992-11-26
CA2001203A1 (fr) 1990-04-24
JP2875015B2 (ja) 1999-03-24
AU4368589A (en) 1990-04-26
US5387748A (en) 1995-02-07
NZ231111A (en) 1992-11-25

Similar Documents

Publication Publication Date Title
DK527789D0 (da) Dithiocarbamoylquinoloner og sammensaetninger omfattende samme
DK659589A (da) Fedtstofsammensaetning og levnedsmiddel omfattende samme
DK330087D0 (da) Solfilter-forbindelse og sammensaetning indeholdende samme
NO177325C (no) Brönnbehandlingsvæske og tilsetningsmiddel
BR8905204A (pt) Composicao colutoria
DK609689D0 (da) Folielaminat og dets anvendelse
DK527589A (da) Antimikrobielle lactam-qinolonforbindelser og sammensaetninger omfattende samme
BR8906787A (pt) Composicao
PT87554A (pt) Didinfecting and sterilizing composition
KR890016965A (ko) 항생작용을 하는 조성물 및 이들의 용도
BR8905444A (pt) Composicoes e aplicacao
DK413187A (da) Semicarbazoner og thiosemicarbazoner
NO893892L (no) Antimikrobiologisk sammensetning og fremgangsmaate for anvendelse.
BR8902491A (pt) Composicao
BR8905729A (pt) Composicao e emprego
DK564189A (da) Insecticidt praeparat og insecticid aerosol
DK501989A (da) Mikrobiocidt praeparat og dettes fremstilling
DK634089D0 (da) Polyhydroxybenzyloxypropanolaminer og deres anvendelse
DK0462123T3 (da) UV-absorberende forbindelser og sammensætninger
BR8900587A (pt) Composicoes
DK619589D0 (da) Sphingenin og derivater heraf
DK94288D0 (da) Stillads og stilladsbuk dertil
DK647089D0 (da) Forbindelser og anvendelse
DK624889D0 (da) Forbindelser og anvendelse
DK90087D0 (da) Stillads og stilladsbuk dertil

Legal Events

Date Code Title Description
ATS Application withdrawn