DK552476A - Glucosaminderivater og fremgangsmade til fremstilling deraf - Google Patents

Glucosaminderivater og fremgangsmade til fremstilling deraf

Info

Publication number
DK552476A
DK552476A DK552476A DK552476A DK552476A DK 552476 A DK552476 A DK 552476A DK 552476 A DK552476 A DK 552476A DK 552476 A DK552476 A DK 552476A DK 552476 A DK552476 A DK 552476A
Authority
DK
Denmark
Prior art keywords
procedures
glucosamine derivatives
glucosamine
derivatives
Prior art date
Application number
DK552476A
Other languages
English (en)
Other versions
DK154654C (da
DK154654B (da
Inventor
G Baschang
A Hartmann
J Stanek
A Sele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK552476A publication Critical patent/DK552476A/da
Publication of DK154654B publication Critical patent/DK154654B/da
Application granted granted Critical
Publication of DK154654C publication Critical patent/DK154654C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK552476A 1975-12-10 1976-12-09 Analogifremgangsmaade til fremstilling af immunmodulerende 2-oe2-acylamino-2-desoxy-(d)-glucosyl-3-oaa-alkancarboxylsyrepeptid-derivater eller farmaceutisk acceptable salte deraf DK154654C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1604275 1975-12-10
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (3)

Publication Number Publication Date
DK552476A true DK552476A (da) 1977-06-11
DK154654B DK154654B (da) 1988-12-05
DK154654C DK154654C (da) 1989-05-08

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK552476A DK154654C (da) 1975-12-10 1976-12-09 Analogifremgangsmaade til fremstilling af immunmodulerende 2-oe2-acylamino-2-desoxy-(d)-glucosyl-3-oaa-alkancarboxylsyrepeptid-derivater eller farmaceutisk acceptable salte deraf

Country Status (30)

Country Link
JP (1) JPS5273820A (da)
AR (2) AR224091A1 (da)
AT (1) AT365607B (da)
AU (1) AU508764B2 (da)
BE (1) BE849214A (da)
CA (1) CA1262400A (da)
CH (2) CH613709A5 (da)
CS (4) CS205025B2 (da)
DD (1) DD129781A5 (da)
DE (1) DE2655500A1 (da)
DK (1) DK154654C (da)
ES (2) ES454118A1 (da)
FI (1) FI64164C (da)
FR (1) FR2361902A1 (da)
GB (1) GB1570625A (da)
GR (1) GR61647B (da)
HK (1) HK32883A (da)
HU (1) HU177970B (da)
IE (1) IE44190B1 (da)
IL (1) IL51076A (da)
MY (1) MY8400123A (da)
NL (1) NL7613666A (da)
NO (1) NO144850C (da)
NZ (1) NZ182837A (da)
PL (4) PL110353B1 (da)
PT (1) PT65946B (da)
SE (1) SE445923B (da)
SG (1) SG11083G (da)
SU (3) SU660589A3 (da)
ZA (1) ZA767333B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
DE3070457D1 (en) * 1979-10-02 1985-05-15 Ciba Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
FI803077A7 (fi) * 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (da) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
RU2181729C1 (ru) * 2000-09-20 2002-04-27 Калюжин Олег Витальевич Производные мурамовой кислоты
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
ES2930246T3 (es) * 2015-12-10 2022-12-09 Bharat Biotech Int Ltd Nuevo compuesto derivado del péptido muramilo, síntesis y utilizaciones del mismo
US12134664B2 (en) 2015-12-10 2024-11-05 Bharat Biotech International Ltd. Muramyl peptide derivatives
CN108883080B (zh) * 2015-12-15 2021-12-21 巴拉特生物技术国际有限公司 胞壁酰肽衍生物化合物、其合成及其用途
WO2019040109A1 (en) 2017-08-21 2019-02-28 Celgene Corporation PROCESSES FOR THE PREPARATION OF (S) -TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Also Published As

Publication number Publication date
CS205027B2 (en) 1981-04-30
AR220686A1 (es) 1980-11-28
NZ182837A (en) 1978-07-28
DE2655500A1 (de) 1977-06-23
HK32883A (en) 1983-09-02
SU660589A3 (ru) 1979-04-30
FI763541A7 (da) 1977-06-11
AT365607B (de) 1982-02-10
CH613709A5 (en) 1979-10-15
NO144850B (no) 1981-08-17
NL7613666A (nl) 1977-06-14
PL112672B1 (en) 1980-10-31
DD129781A5 (de) 1978-02-08
PL194291A1 (pl) 1978-10-23
CS205025B2 (en) 1981-04-30
IL51076A0 (en) 1977-02-28
IE44190B1 (en) 1981-09-09
SG11083G (en) 1983-09-16
FI64164C (fi) 1983-10-10
CH614718A5 (en) 1979-12-14
GB1570625A (en) 1980-07-02
MY8400123A (en) 1984-12-31
FR2361902A1 (fr) 1978-03-17
SE445923B (sv) 1986-07-28
FR2361902B1 (da) 1980-11-07
FI64164B (fi) 1983-06-30
AR224091A1 (es) 1981-10-30
SU1060118A3 (ru) 1983-12-07
CA1262400A (en) 1989-10-17
BE849214A (fr) 1977-06-09
PT65946B (en) 1978-06-14
NO764191L (da) 1977-06-13
DK154654C (da) 1989-05-08
GR61647B (en) 1978-12-05
SE7613851L (sv) 1977-06-11
IE44190L (en) 1977-06-10
IL51076A (en) 1980-09-16
CS205028B2 (en) 1981-04-30
AU508764B2 (en) 1980-04-03
ES454118A1 (es) 1978-03-01
PL110787B1 (en) 1980-07-31
ES465514A1 (es) 1978-09-16
HU177970B (en) 1982-02-28
PL110794B1 (en) 1980-07-31
DK154654B (da) 1988-12-05
SU747430A3 (ru) 1980-07-23
CS205026B2 (en) 1981-04-30
DE2655500C2 (da) 1988-12-22
NO144850C (no) 1981-11-25
PT65946A (en) 1977-01-01
JPS638118B2 (da) 1988-02-19
ATA909276A (de) 1981-06-15
AU2042276A (en) 1978-06-15
PL110353B1 (en) 1980-07-31
ZA767333B (en) 1977-11-30
JPS5273820A (en) 1977-06-21

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PBP Patent lapsed