DK562685D0 - Transformationssystem - Google Patents

Transformationssystem

Info

Publication number
DK562685D0
DK562685D0 DK562685A DK562685A DK562685D0 DK 562685 D0 DK562685 D0 DK 562685D0 DK 562685 A DK562685 A DK 562685A DK 562685 A DK562685 A DK 562685A DK 562685 D0 DK562685 D0 DK 562685D0
Authority
DK
Denmark
Prior art keywords
niger
dna
transformation
selectable marker
vector
Prior art date
Application number
DK562685A
Other languages
English (en)
Other versions
DK175213B1 (da
DK562685A (da
Inventor
Francis Paul Buxton
David Ivor Gwynne
Roger Wayne Davies
Original Assignee
Allelix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24723387&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK562685(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allelix Inc filed Critical Allelix Inc
Publication of DK562685D0 publication Critical patent/DK562685D0/da
Publication of DK562685A publication Critical patent/DK562685A/da
Application granted granted Critical
Publication of DK175213B1 publication Critical patent/DK175213B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y10S435/917—Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Vehicle Body Suspensions (AREA)
  • Control Of Eletrric Generators (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK198505626A 1984-12-05 1985-12-04 Fremgangsmåde til fremstilling af transformanter af fungusarten Aspergillus niger og transformanter af fungusarten Aspergillus niger DK175213B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67857884 1984-12-05
US06/678,578 US4885249A (en) 1984-12-05 1984-12-05 Aspergillus niger transformation system

Publications (3)

Publication Number Publication Date
DK562685D0 true DK562685D0 (da) 1985-12-04
DK562685A DK562685A (da) 1986-06-06
DK175213B1 DK175213B1 (da) 2004-07-12

Family

ID=24723387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198505626A DK175213B1 (da) 1984-12-05 1985-12-04 Fremgangsmåde til fremstilling af transformanter af fungusarten Aspergillus niger og transformanter af fungusarten Aspergillus niger

Country Status (8)

Country Link
US (1) US4885249A (da)
EP (1) EP0184438B1 (da)
JP (1) JPS61162168A (da)
AT (1) ATE82772T1 (da)
AU (1) AU590733B2 (da)
CA (1) CA1341342C (da)
DE (1) DE3586858T2 (da)
DK (1) DK175213B1 (da)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723292A (en) * 1984-05-25 1998-03-03 Zymogenetics, Inc. Stable DNA constructs
US6004785A (en) 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US5766912A (en) 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
FI872102L (fi) * 1986-06-06 1987-12-07 Panlabs Inc Expressionssystem hos filamentala fungi.
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
GB8702475D0 (en) 1987-02-04 1987-03-11 Ciba Geigy Ag Expression system
DE3854249T2 (de) * 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JP2748347B2 (ja) * 1989-03-09 1998-05-06 キッコーマン 株式会社 アスペルギルス・ソーヤ形質転換体
FI103206B (fi) * 1990-01-29 1999-05-14 Novartis Ag Uusi ilmentämisjärjestelmä sieniä varten
US5290474A (en) * 1990-10-05 1994-03-01 Genencor International, Inc. Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
CA2093422C (en) * 1990-10-05 2001-04-03 Genencor International, Inc. DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS
DE69331121T2 (de) * 1992-03-09 2002-07-11 Oji Paper Co., Ltd. Ornithin-Carbamoyl-Transferase Gen und seine Verwendung als Gen-Marker in einem Expression-System für die Herstellung von Proteinen bei Basidiomyceten
DK36592D0 (da) * 1992-03-20 1992-03-20 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
US5846802A (en) * 1992-04-15 1998-12-08 Buxton; Frank Fungal Protease
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US6268140B1 (en) 1994-02-03 2001-07-31 Neugenesis Combinatorial metabolic libraries
US5643745A (en) * 1994-02-03 1997-07-01 University Of Hawaii Heterologous dimeric proteins produced in heterokaryons
US5683899A (en) 1994-02-03 1997-11-04 University Of Hawaii Methods and compositions for combinatorial-based discovery of new multimeric molecules
AU2733895A (en) * 1994-06-17 1996-01-15 Novo Nordisk A/S A fungus wherein the area gene has been modified and an area gene from aspergillus oryzae
DK0767837T3 (da) * 1994-06-29 2004-03-15 Dsm Ip Assets Bv Forøget produktion af b-galactosidase i Aspergillus Oryzae
CN1160465C (zh) * 1995-12-15 2004-08-04 诺沃奇梅兹有限公司 其中areA、pepC和/或pepE基因已被灭活的真菌
US5776730A (en) * 1995-12-15 1998-07-07 University Of Hawaii Neurospora hosts for the production of recombinant proteins, and methods for producing same
WO2000020555A2 (en) * 1998-10-06 2000-04-13 Aarl Inc Transformation system in the field of filamentous fungal hosts: in chrysosporium
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US8372620B2 (en) 1998-12-23 2013-02-12 Dupont Nutrition Biosciences Aps Bacterial xylanases
ATE529502T1 (de) * 1999-08-13 2011-11-15 Suntory Holdings Ltd Lipidausscheidender mikroorganismus und verfahren zur herstellung des lipids und lipidkugeln mit darin eingeschlossenem lipid durch verwendung von mikroorganismen
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
PT1326957E (pt) 2000-12-07 2004-09-30 Dsm Ip Assets Bv Metodo para a prevencao ou reducao de turvacao em bebidas
CA2437081C (en) 2000-12-07 2010-10-19 Dsm Ip Assets B.V. Protein hydrolysates enriched in peptides having a carboxy terminal proline residue
IL157842A0 (en) 2001-03-22 2004-03-28 Novo Nordisk Healthcare Ag Coagulation factor vii derivatives
GB0116453D0 (en) 2001-07-05 2001-08-29 Imp College Innovations Ltd Method
JP4088097B2 (ja) * 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
EP1511835B9 (en) 2002-06-07 2015-02-25 DSM IP Assets B.V. Improved method for the prevention or reduction of haze in beverages
AU2003258395A1 (en) * 2002-08-30 2004-03-19 Puratos Naamloze Vennootschap Myrothecium sp. transformation and expression system
JP2007526748A (ja) 2003-06-25 2007-09-20 ノボザイムス アクティーゼルスカブ 澱粉加工用酵素
ES2517245T3 (es) 2003-06-25 2014-11-03 Novozymes A/S Enzimas para el tratamiento de almidón
EP2392655A3 (en) 2003-09-09 2012-02-29 Novo Nordisk Health Care AG Coagulation factor VII polypeptides
US8323014B2 (en) * 2003-10-31 2012-12-04 Pirelli Pneumatici S.P.A. Expandable bladder for tyre-curing apparatuses, a manufacturing method thereof, and a process for manufacturing tyres for vehicle wheels
US20050181509A1 (en) * 2004-02-12 2005-08-18 The Penn State Research Foundation Dual selection based, targeted gene disruption method for fungi and fungus-like organisms
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
US8163533B2 (en) * 2004-10-15 2012-04-24 Intrexon Corporation Methods and compositions for combinatorial-based production of multivalent recombinant antigens
ES2543131T3 (es) 2004-12-22 2015-08-14 Novozymes North America, Inc. Enzimas para tratamiento de almidón
CN1298837C (zh) * 2005-07-28 2007-02-07 秘鸣 一种黑曲霉真菌及其在普洱茶生产中的应用
WO2007031559A2 (en) 2005-09-14 2007-03-22 Novo Nordisk Health Care Ag Human coagulation factor vii polypeptides
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
CN101292024B (zh) 2005-10-17 2012-04-18 诺维信公司 用于表达抗体的真菌突变体的用途
EP3563688A1 (en) 2005-11-28 2019-11-06 DSM IP Assets B.V. Enzyme preparations yielding a clean taste
GB0600406D0 (en) 2006-01-10 2006-02-15 Univ Bath Crystal
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
US8680252B2 (en) 2006-12-10 2014-03-25 Dyadic International (Usa), Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
NZ578309A (en) 2007-01-30 2012-06-29 Verenium Corp Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
JP5436225B2 (ja) 2007-02-20 2014-03-05 ディーエスエム アイピー アセッツ ビー．ブイ． 新規シアリダーゼ
DK2126060T3 (da) 2007-03-22 2017-01-16 Dsm Ip Assets Bv Hidtil ukendte lysyloxidaser
CA2695830A1 (en) 2007-08-08 2009-02-12 Novozymes Biopharma Dk A/S Transferrin variants and conjugates
CA2736661A1 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
CN108530543B (zh) 2009-02-03 2023-06-23 阿穆尼克斯制药公司 延伸重组多肽和包含该延伸重组多肽的组合物
WO2010089385A1 (en) 2009-02-06 2010-08-12 Novozymes Biopharma Dk A/S Purification process
WO2010092135A2 (en) 2009-02-11 2010-08-19 Novozymes Biopharma Uk Ltd. Albumin variants and conjugates
WO2011006982A2 (en) 2009-07-17 2011-01-20 Rigshospitalet Inhibitors of complement activation
CN102741275B (zh) 2009-08-24 2016-08-03 阿穆尼克斯运营公司 凝血因子ix组合物及其制备和使用方法
US9096843B2 (en) 2009-12-01 2015-08-04 Novo Nordisk A/S Peptidyl α-hydroxyglycine α-amidating lyases
WO2011101339A2 (en) 2010-02-18 2011-08-25 Dsm Ip Assets B.V. Fermentation broth and filtration filter cake and uses thereof
US9815876B2 (en) 2010-03-05 2017-11-14 Omeros Corporation Chimeric inhibitor molecules of complement activation
WO2012007445A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Mutarotase in crystallization
WO2012007446A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Use of a mutarotase in the production of dried powders
BR112013008347A2 (pt) 2010-10-06 2016-06-14 Bp Corp North America Inc polipeptídeos de variantes cbh i
EP3431098A1 (en) 2011-09-12 2019-01-23 Amunix Operating Inc. Glucagon-like peptide-2 compositions and methods of making and using same
JP6517018B2 (ja) 2012-02-09 2019-05-22 ヴァー２・ファーマシューティカルズ・アンパルトセルスカブＶＡＲ２ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ ＡｐＳ コンドロイチン硫酸グリカンのターゲティング
EP2822577B1 (en) 2012-02-15 2019-02-06 Bioverativ Therapeutics Inc. Recombinant factor viii proteins
LT3564260T (lt) 2012-02-15 2023-01-10 Bioverativ Therapeutics Inc. Viii faktoriaus kompozicijos ir jų gamybos bei panaudojimo būdai
JP2015532307A (ja) 2012-10-15 2015-11-09 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 凝固因子ｖｉｉポリペプチド
TWI667255B (zh) 2013-08-14 2019-08-01 美商生物化學醫療公司 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途
SG11201605242YA (en) 2014-01-10 2016-07-28 Biogen Ma Inc Factor viii chimeric proteins and uses thereof
IL257231B (en) 2015-08-03 2022-09-01 Bioverativ Therapeutics Inc Factor ix fusion proteins and methods of making and using same
MX2019006444A (es) 2016-12-02 2019-10-30 Bioverativ Therapeutics Inc Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos.
SI3793588T1 (sl) 2018-05-18 2025-07-31 Bioverativ Therapeutics Inc. Postopki zdravljenja hemofilije A
US20210278406A1 (en) 2018-07-13 2021-09-09 Varct Diagnostic Aps Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
CN114958899A (zh) * 2022-05-30 2022-08-30 福州大学 一种能在黑曲霉细胞内自主复制的复制子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486533A (en) * 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
EP0191221A1 (en) * 1984-10-24 1986-08-20 The Regents Of The University Of California Vectors for transformation of ascomycetes
US4735901A (en) * 1985-01-14 1988-04-05 E. R. Squibb & Sons, Inc. Transformation of Candida albicans
EP0625577A1 (en) * 1985-08-29 1994-11-23 Genencor International, Inc. Heterologous polypeptides expressed in filamentous fungi, processes for their preparation, and vectors for their preparation
FI864473L (fi) * 1985-11-20 1987-05-21 Panlabs Inc Sammansatta yttryckskassetter foer fungaltransformering.
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus

Also Published As

Publication number Publication date
EP0184438A2 (en) 1986-06-11
AU5078085A (en) 1986-06-12
CA1341342C (en) 2002-02-26
DK175213B1 (da) 2004-07-12
US4885249A (en) 1989-12-05
JPS61162168A (ja) 1986-07-22
AU590733B2 (en) 1989-11-16
EP0184438A3 (en) 1988-01-13
EP0184438B1 (en) 1992-11-25
DK562685A (da) 1986-06-06
ATE82772T1 (de) 1992-12-15
DE3586858T2 (de) 1993-05-19
DE3586858D1 (de) 1993-01-07

Similar Documents

Publication Publication Date Title
DK562685A (da) Transformationssystem
EP0249676A3 (en) Method for the expression of genes in plants
IT8023051A0 (it) Particelle sferiche di carbone attivato adatte all'impiego in composizioni farmaceutiche controle intossicazioni.
DE3587168D1 (de) Glucoamylasegen.
KR910001064A (ko) 열 안정성을 갖는 시토신 탈(脫) 아민 효소
ES2150188T3 (es) Procedimiento para la preparacion de una proteina mediante un hongo transformado por integracion multicopia de un vector de expresion.
MY8600605A (en) Agent for the detection of esterolytic and/or proteolytic enzymes and phenoxyamino acid and phenoxy peptide esters suitable as substrates therefor processes for their preparation as well as their use for the preparation of the agent according to the invention.
NO863458D0 (no) Undertrykkbare gjaerpromotorer.
Reiss et al. Isocitrate lyase from the free-living nematode, Turbatrix aceti. Purification and properties
IE840258L (en) Expression of gene products.
DE2963374D1 (en) Recombinant dna, method for preparing it and production of foreign proteins by unicellular hosts containing it
GB1530651A (en) Glass
JPS5658488A (en) Refined "sake" with low alcohol content
EP0138428A3 (en) Acid-stable alpha-amylase composition, preparation and use thereof
GR3033685T3 (en) Mutant interleukin 6 with improved biological activity over wild interleukin 6.
EP0240224A3 (en) An alpha interferon analogue
Killick Trehalase from the cellular slime mold Dictyostelium discoideum: purification and characterization of the homogeneous enzyme from myxamoebae
ES8606402A1 (es) Un procedimiento para preparar una molecula de adn recom- biante
ES8802248A1 (es) Procedimiento para la preparacion de penicilin-g-amidasa por expresion de la enzima en el seno de un microorganismo.
Pannerselvam et al. Purification and some properties of an acid carboxypeptidase from Aspergillus fumigatus.
JPS5437894A (en) Preparation of liquid flavor
Jervis Characterization of potato (Solanum tuberosum) lactate dehydrogenase isoenzymes by affinity chromatography and hybridization
Paberit et al. Isolation and properties of neutral metalloprotease from thermophilic bacteria Bacillus brevis.
SE7705701L (sv) Forfarande for utvinning av eggvita med forminskad nukleinsyrahalt ur mikroorganismer
JPS5783283A (en) Novel yeast

Legal Events

Date Code Title Description
PPF Opposition filed
PUP Patent expired
PUG Patent revoked