DK562685D0 - Transformationssystem - Google Patents

Transformationssystem

Info

Publication number
DK562685D0
DK562685D0 DK562685A DK562685A DK562685D0 DK 562685 D0 DK562685 D0 DK 562685D0 DK 562685 A DK562685 A DK 562685A DK 562685 A DK562685 A DK 562685A DK 562685 D0 DK562685 D0 DK 562685D0
Authority
DK
Denmark
Prior art keywords
niger
dna
transformation
selectable marker
vector
Prior art date
Application number
DK562685A
Other languages
English (en)
Other versions
DK562685A (da
DK175213B1 (da
Inventor
Francis Paul Buxton
David Ivor Gwynne
Roger Wayne Davies
Original Assignee
Allelix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24723387&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK562685(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allelix Inc filed Critical Allelix Inc
Publication of DK562685D0 publication Critical patent/DK562685D0/da
Publication of DK562685A publication Critical patent/DK562685A/da
Application granted granted Critical
Publication of DK175213B1 publication Critical patent/DK175213B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y10S435/917—Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Vehicle Body Suspensions (AREA)
  • Control Of Eletrric Generators (AREA)
DK198505626A 1984-12-05 1985-12-04 Fremgangsmåde til fremstilling af transformanter af fungusarten Aspergillus niger og transformanter af fungusarten Aspergillus niger DK175213B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/678,578 US4885249A (en) 1984-12-05 1984-12-05 Aspergillus niger transformation system
US67857884 1984-12-05

Publications (3)

Publication Number Publication Date
DK562685D0 true DK562685D0 (da) 1985-12-04
DK562685A DK562685A (da) 1986-06-06
DK175213B1 DK175213B1 (da) 2004-07-12

Family

ID=24723387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198505626A DK175213B1 (da) 1984-12-05 1985-12-04 Fremgangsmåde til fremstilling af transformanter af fungusarten Aspergillus niger og transformanter af fungusarten Aspergillus niger

Country Status (8)

Country Link
US (1) US4885249A (da)
EP (1) EP0184438B1 (da)
JP (1) JPS61162168A (da)
AT (1) ATE82772T1 (da)
AU (1) AU590733B2 (da)
CA (1) CA1341342C (da)
DE (1) DE3586858T2 (da)
DK (1) DK175213B1 (da)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723292A (en) * 1984-05-25 1998-03-03 Zymogenetics, Inc. Stable DNA constructs
US6004785A (en) 1985-08-29 1999-12-21 Genencor International Inc. Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same
US5364770A (en) * 1985-08-29 1994-11-15 Genencor International Inc. Heterologous polypeptides expressed in aspergillus
US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
US5766912A (en) * 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
FI872102A7 (fi) * 1986-06-06 1987-12-07 Panlabs Inc Rihmasienten ilmentymisjärjestelmät.
GB8702475D0 (en) 1987-02-04 1987-03-11 Ciba Geigy Ag Expression system
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
EP0305216B1 (en) * 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
JP2748347B2 (ja) * 1989-03-09 1998-05-06 キッコーマン 株式会社 アスペルギルス・ソーヤ形質転換体
ZA909987B (en) * 1990-01-29 1991-09-25 Ciba Geigy Novel fungal expression system
US5290474A (en) * 1990-10-05 1994-03-01 Genencor International, Inc. Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
CA2093422C (en) * 1990-10-05 2001-04-03 Genencor International, Inc. DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS
CA2091236C (en) * 1992-03-09 2000-06-20 Akira Tsukamoto Ornithine carbamoyl transferase gene and utilization of the dna
DK36592D0 (da) * 1992-03-20 1992-03-20 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
US5846802A (en) * 1992-04-15 1998-12-08 Buxton; Frank Fungal Protease
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US5643745A (en) * 1994-02-03 1997-07-01 University Of Hawaii Heterologous dimeric proteins produced in heterokaryons
US6268140B1 (en) 1994-02-03 2001-07-31 Neugenesis Combinatorial metabolic libraries
US5683899A (en) * 1994-02-03 1997-11-04 University Of Hawaii Methods and compositions for combinatorial-based discovery of new multimeric molecules
CN1253574C (zh) * 1994-06-17 2006-04-26 诺沃奇梅兹有限公司 来自米曲霉的areA基因和其中areA基因已被修饰的真菌
DK0767837T3 (da) * 1994-06-29 2004-03-15 Dsm Ip Assets Bv Forøget produktion af b-galactosidase i Aspergillus Oryzae
US5776730A (en) * 1995-12-15 1998-07-07 University Of Hawaii Neurospora hosts for the production of recombinant proteins, and methods for producing same
AU1092897A (en) * 1995-12-15 1997-07-14 Novo Nordisk A/S A funguns wherein the area, pepc and/or pepe genes have been inactivated
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
ATE286136T1 (de) * 1998-10-06 2005-01-15 Mark Aaron Emalfarb Transformationsystem in filamentösen fungiziden chrysosporium-wirtszellen
US20050079573A1 (en) 1998-12-23 2005-04-14 Danisco A/S Proteins
EP1122304B1 (en) * 1999-08-13 2011-10-19 Suntory Holdings Limited Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the microorganism
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
DE60103174T2 (de) 2000-12-07 2005-05-12 Dsm Ip Assets B.V. Verfahren zur verhinderung oder verminderung der trübung in getränken
DK1339837T3 (da) 2000-12-07 2008-06-09 Dsm Ip Assets Bv Prolyl-endoprotease fra Aspergillus Niger
ES2432967T3 (es) 2001-03-22 2013-12-05 Novo Nordisk Health Care Ag Derivados del Factor VII de coagulación
GB0116453D0 (en) 2001-07-05 2001-08-29 Imp College Innovations Ltd Method
JP4088097B2 (ja) * 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
CA2490020C (en) 2002-06-07 2011-01-04 Dsm Ip Assets B.V. Improved method for the prevention or reduction of haze in beverages
US20060240509A1 (en) * 2002-08-30 2006-10-26 Jean-Luc Jonniaux Myrothecium sp transformation and expression system
ATE510925T1 (de) 2003-06-25 2011-06-15 Novozymes As Stärkehydrolyseverfahren
MXPA06000212A (es) 2003-06-25 2006-03-21 Novozymes As Enzimas para procesar almidon.
CN101870729A (zh) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 凝固因子ⅶ多肽
JP4359286B2 (ja) * 2003-10-31 2009-11-04 ピレリ・タイヤ・ソチエタ・ペル・アツィオーニ タイヤ加硫装置用の膨張性ブラダ、その製造方法、及び車輪用のタイヤを製造するプロセス
US20050181509A1 (en) * 2004-02-12 2005-08-18 The Penn State Research Foundation Dual selection based, targeted gene disruption method for fungi and fungus-like organisms
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
JP5060958B2 (ja) 2004-10-15 2012-10-31 イントレキソン コーポレーション 多価組換え抗原のコンビナトリアルベースの生産のための方法および組成物
MX2007007107A (es) 2004-12-22 2007-08-08 Novozymes North America Inc Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que los codifican.
CN1298837C (zh) * 2005-07-28 2007-02-07 秘鸣 一种黑曲霉真菌及其在普洱茶生产中的应用
JP5690047B2 (ja) 2005-09-14 2015-03-25 ノボ ノルディスク ヘルス ケア アーゲー ヒト凝固第ｖｉｉ因子ポリペプチド
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
DK1941025T3 (da) 2005-10-17 2011-09-26 Novozymes As Brug af svampemutanter til ekspression af antistoffer
US9011948B2 (en) 2005-11-28 2015-04-21 Dsm Ip Assets B.V. Enzyme preparations yielding a clean taste
GB0600406D0 (en) 2006-01-10 2006-02-15 Univ Bath Crystal
EP2505651A3 (en) 2006-12-10 2013-01-09 Dyadic International, Inc. Isolated fungus with reduced protease activity
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
CN104212822A (zh) 2007-01-30 2014-12-17 Bp法人北美有限公司 用于处理木质纤维素的酶、编码它们的核酸及其制备和应用方法
CA2676686C (en) 2007-02-20 2015-12-15 Dsm Ip Assets B.V. Novel sialidase
ES2608033T3 (es) 2007-03-22 2017-04-05 Dsm Ip Assets B.V. Nuevas lisil oxidasas
EP2594583A1 (en) 2007-08-08 2013-05-22 Novozymes Biopharma DK A/S Transferrin variants and conugates
WO2009033071A2 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
DK3178835T3 (da) 2009-02-03 2019-06-24 Amunix Pharmaceuticals Inc Forlængede rekombinante polypeptider og sammensætninger omfattende samme
US20110294988A1 (en) 2009-02-06 2011-12-01 Novozymes Bio Pharma DK A/S Purification Process
SG172789A1 (en) 2009-02-11 2011-08-29 Novozymes Biopharma Dk As Albumin variants and conjugates
CA2767755C (en) 2009-07-17 2021-10-12 Rigshospitalet Inhibitors of complement activation
CA2771999A1 (en) 2009-08-24 2011-03-10 Amunix Operating Inc. Coagulation factor vii compositions and methods of making and using same
ES2583259T3 (es) 2009-12-01 2016-09-20 Novo Nordisk A/S Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina
WO2011101339A2 (en) 2010-02-18 2011-08-25 Dsm Ip Assets B.V. Fermentation broth and filtration filter cake and uses thereof
AU2011222883B2 (en) 2010-03-05 2016-05-26 Omeros Corporation Chimeric inhibitor molecules of complement activation
WO2012007446A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Use of a mutarotase in the production of dried powders
WO2012007445A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Mutarotase in crystallization
CA2811787A1 (en) 2010-10-06 2012-04-19 Bp Corporation North America Inc. Variant cbh i polypeptides
ES2687651T3 (es) 2011-09-12 2018-10-26 Amunix Operating Inc. Composiciones de péptido-2 similar a glucagón y métodos para producir y usar los mismos
PL2812024T3 (pl) 2012-02-09 2018-09-28 Var2 Pharmaceuticals Aps Celowanie glikanów siarczanu chondroityny
WO2013123457A1 (en) 2012-02-15 2013-08-22 Biogen Idec Ma Inc. Recombinant factor viii proteins
CN111548418A (zh) 2012-02-15 2020-08-18 比奥贝拉蒂治疗公司 因子viii组合物及其制备和使用方法
CN104704118A (zh) 2012-10-15 2015-06-10 诺和诺德保健Ag（股份有限公司） 凝血因子vii多肽
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
EA201691111A1 (ru) 2014-01-10 2017-01-30 Байоджен Ма Инк. Химерные белки фактора viii и их применение
UA126016C2 (uk) 2015-08-03 2022-08-03 Біовератів Терапеутікс Інк. Злитий білок фактора іх
KR20190090827A (ko) 2016-12-02 2019-08-02 바이오버라티브 테라퓨틱스 인크. 키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법
KR102914074B1 (ko) 2018-05-18 2026-01-16 바이오버라티브 테라퓨틱스 인크. A형 혈우병의 치료 방법
CN112789504A (zh) 2018-07-13 2021-05-11 瓦克特诊断有限责任公司 使用重组疟疾蛋白var2csa分离胎儿来源的循环细胞
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
CN114958899A (zh) * 2022-05-30 2022-08-30 福州大学 一种能在黑曲霉细胞内自主复制的复制子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486533A (en) * 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
EP0191221A1 (en) * 1984-10-24 1986-08-20 The Regents Of The University Of California Vectors for transformation of ascomycetes
US4735901A (en) * 1985-01-14 1988-04-05 E. R. Squibb & Sons, Inc. Transformation of Candida albicans
NZ217373A (en) * 1985-08-29 1990-10-26 Genencor Inc Production of heterologous peptide in filamentous fungi, vectors and dna
FI864473A7 (fi) * 1985-11-20 1987-05-21 Panlabs Inc Yhdistetyt ilmaisukasetit fungaalitransformaatiota varten.
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus

Also Published As

Publication number Publication date
ATE82772T1 (de) 1992-12-15
JPS61162168A (ja) 1986-07-22
DE3586858D1 (de) 1993-01-07
US4885249A (en) 1989-12-05
EP0184438A2 (en) 1986-06-11
EP0184438A3 (en) 1988-01-13
EP0184438B1 (en) 1992-11-25
DK562685A (da) 1986-06-06
AU5078085A (en) 1986-06-12
DE3586858T2 (de) 1993-05-19
DK175213B1 (da) 2004-07-12
AU590733B2 (en) 1989-11-16
CA1341342C (en) 2002-02-26

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