DK567778A - Fremgangsmaade til fremstilling af kvaternaere ammoniumsalte af phenylpropylaminer og phenylbutylaminer - Google Patents

Fremgangsmaade til fremstilling af kvaternaere ammoniumsalte af phenylpropylaminer og phenylbutylaminer

Info

Publication number
DK567778A
DK567778A DK567778A DK567778A DK567778A DK 567778 A DK567778 A DK 567778A DK 567778 A DK567778 A DK 567778A DK 567778 A DK567778 A DK 567778A DK 567778 A DK567778 A DK 567778A
Authority
DK
Denmark
Prior art keywords
quateran
phenylbutylamines
phenylpropylamines
procedure
preparation
Prior art date
Application number
DK567778A
Other languages
English (en)
Other versions
DK150475B (da
DK150475C (da
Inventor
B B Molloy
M I Steinberg
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK567778A publication Critical patent/DK567778A/da
Publication of DK150475B publication Critical patent/DK150475B/da
Application granted granted Critical
Publication of DK150475C publication Critical patent/DK150475C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/037—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements with quaternary ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK567778A 1977-12-19 1978-12-18 Analogifremgangsmaade til fremstilling af kvaternaere ammoniumsalte af phenylbutylaminer DK150475C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86178977A 1977-12-19 1977-12-19
US86178977 1977-12-19

Publications (3)

Publication Number Publication Date
DK567778A true DK567778A (da) 1979-07-31
DK150475B DK150475B (da) 1987-03-09
DK150475C DK150475C (da) 1987-10-26

Family

ID=25336767

Family Applications (1)

Application Number Title Priority Date Filing Date
DK567778A DK150475C (da) 1977-12-19 1978-12-18 Analogifremgangsmaade til fremstilling af kvaternaere ammoniumsalte af phenylbutylaminer

Country Status (28)

Country Link
EP (1) EP0002604B1 (da)
JP (1) JPS5495520A (da)
AR (1) AR222813A1 (da)
AT (1) AT363065B (da)
AU (1) AU524727B2 (da)
BE (1) BE872832A (da)
CA (1) CA1093072A (da)
CH (1) CH640506A5 (da)
CS (1) CS857778A2 (da)
DD (1) DD139842A5 (da)
DE (1) DE2862243D1 (da)
DK (1) DK150475C (da)
EG (1) EG14601A (da)
ES (1) ES476152A1 (da)
FI (1) FI65425C (da)
FR (1) FR2411824A1 (da)
GB (1) GB2011388B (da)
HU (1) HU178220B (da)
IE (1) IE47693B1 (da)
IL (1) IL56212A (da)
LU (1) LU80670A1 (da)
NZ (1) NZ189162A (da)
PH (1) PH14394A (da)
PT (1) PT68907A (da)
RO (1) RO76881A2 (da)
SU (1) SU745360A3 (da)
YU (1) YU297578A (da)
ZA (1) ZA787111B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336269A (en) 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines
DE2952382A1 (de) * 1979-12-24 1981-07-16 Basf Ag, 6700 Ludwigshafen Phenylpropylammoniumsalze, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
EP0074005B1 (de) * 1981-08-29 1985-05-02 BASF Aktiengesellschaft Phenylpropylammoniumsalz enthaltende Fungizide und Verfahren zur Bekämpfung von Pilzen
DE3421810A1 (de) * 1984-06-12 1985-12-12 Basf Ag, 6700 Ludwigshafen Phenylalkylamine - bioregulatoren
JPS61140547A (ja) * 1984-12-13 1986-06-27 Seitai Kagaku Kenkyusho:Kk フェネチルアミン誘導体および診断・治療剤
JPH02268142A (ja) * 1989-04-10 1990-11-01 Toubishi Yakuhin Kogyo Kk 筋弛緩作用を有する新規化合物及びその製造方法
EP1207882A4 (en) * 1999-07-30 2003-03-19 Vertex Pharma DERIVATIVES OF ACYCLIC AND CYCLIC AMINES
TWI356054B (en) * 2004-03-31 2012-01-11 Activus Pharma Co Ltd Quaternary ammonium compound, producing method the

Also Published As

Publication number Publication date
GB2011388A (en) 1979-07-11
RO76881A2 (ro) 1981-08-30
HU178220B (en) 1982-03-28
DK150475B (da) 1987-03-09
ATA904378A (de) 1980-12-15
AU524727B2 (en) 1982-09-30
ES476152A1 (es) 1980-05-16
YU297578A (en) 1982-10-31
FI65425C (fi) 1984-05-10
CH640506A5 (fr) 1984-01-13
AT363065B (de) 1981-07-10
PT68907A (en) 1979-01-01
CA1093072A (en) 1981-01-06
FR2411824B1 (da) 1985-03-29
IE782489L (en) 1979-06-19
FR2411824A1 (fr) 1979-07-13
EG14601A (en) 1984-09-30
DD139842A5 (de) 1980-01-23
ZA787111B (en) 1980-08-27
EP0002604A1 (en) 1979-06-27
FI65425B (fi) 1984-01-31
IL56212A (en) 1982-08-31
DK150475C (da) 1987-10-26
PH14394A (en) 1981-06-25
FI783845A7 (fi) 1979-06-20
CS857778A2 (en) 1985-07-16
AR222813A1 (es) 1981-06-30
SU745360A3 (ru) 1980-06-30
NZ189162A (en) 1980-10-24
LU80670A1 (fr) 1979-04-13
JPS5495520A (en) 1979-07-28
DE2862243D1 (en) 1983-06-09
IE47693B1 (en) 1984-05-30
BE872832A (fr) 1979-06-18
AU4255478A (en) 1979-06-28
JPS6214538B2 (da) 1987-04-02
EP0002604B1 (en) 1983-05-04
IL56212A0 (en) 1979-03-12
GB2011388B (en) 1982-04-28

Similar Documents

Publication Publication Date Title
DK110778A (da) Fremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer
DK180878A (da) Fremgangsmaade til fremstilling af imidazoaziner og imidazodiaziner
DK306978A (da) Fremgangsmaade til fremstilling af 1-acyl-2-cyanaziridiner
DK275178A (da) Fremgangsmaade til fremstilling af lipopeptider og anvendelse deraf
DK484677A (da) Fremgangsmaade til fremstilling af furokumariner
DK569678A (da) Fremgangsmaade til fremstilling af 2alfa-cyano-3-oxosteroider
DK145701C (da) Fremgangsmaade til fremstilling af ergotalkaloider
DK496977A (da) Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
DK466878A (da) Fremgangsmaade til fremstilling af 0-methallyloxyphenol
DK237978A (da) Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer
DK154949C (da) Fremgangsmaade til fremstilling af trifluormethylphenoler
DK436978A (da) Fremgangsmaade til fremstilling af sarcosinoxidase
DK267078A (da) Fremgangsmaade til fremstilling af n1-glucofuranosid-6-yl-n3-n3-nitrosourinstoffer og derivater deraf
DK74578A (da) Fremgangsmaade til fremstilling af substituerede pyrroloquinoxalioner og pyrrolobenzodiazepioner
DK364578A (da) Fremgangsmaade til fremstilling af hydroxyphenylhydantoin
DK248978A (da) Fremgangsmaade til fremstilling af hydroxy-alfa-aminobenzylpenicillin
DK319178A (da) Fremgangsmaade til fremstilling af acylamido-2-cephem-4-carboxylsyreforbindelser og salte
FI783845A7 (fi) Kvaternaera ammonium-anti-arrytmiska mediciner
DK333279A (da) Fremgangsmaade til fremstilling af thiosubstitituerede diazacycloalkener og salte deraf
DK196878A (da) Fremgangsmaade til fremstilling af phenylglycinderivater og salte deraf
DK143273C (da) Analogifremgangsmaade til fremstilling af amidinobenzyloyrimidiner og syreadditionssalte heraf
DK383978A (da) Fremgangsmaade til fremstilling af 2-chlorsulfinylazetidin-4-oner
DK339777A (da) Fremgangsmaade til fremstilling af 2-benzylperhydroazepiner
DK158976C (da) Fremgangsmaade til fremstilling af alfa-cyanobenzyl
DK206178A (da) Fremgangsmaade til fremstilling af 3-bromphthalid