DK570689A - Imidazolderivater - Google Patents

Imidazolderivater

Info

Publication number
DK570689A
DK570689A DK570689A DK570689A DK570689A DK 570689 A DK570689 A DK 570689A DK 570689 A DK570689 A DK 570689A DK 570689 A DK570689 A DK 570689A DK 570689 A DK570689 A DK 570689A
Authority
DK
Denmark
Prior art keywords
substituted
compound
formula
unsubstituted
moiety
Prior art date
Application number
DK570689A
Other languages
Danish (da)
English (en)
Other versions
DK570689D0 (da
Inventor
Harald Maschler
Rolf Theodor Wilke
Johannes Jukna
Original Assignee
Beecham Wuelfing Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Wuelfing Gmbh & Co Kg filed Critical Beecham Wuelfing Gmbh & Co Kg
Publication of DK570689D0 publication Critical patent/DK570689D0/da
Publication of DK570689A publication Critical patent/DK570689A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK570689A 1988-11-14 1989-11-14 Imidazolderivater DK570689A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888826595A GB8826595D0 (en) 1988-11-14 1988-11-14 Active compounds

Publications (2)

Publication Number Publication Date
DK570689D0 DK570689D0 (da) 1989-11-14
DK570689A true DK570689A (da) 1990-05-15

Family

ID=10646826

Family Applications (1)

Application Number Title Priority Date Filing Date
DK570689A DK570689A (da) 1988-11-14 1989-11-14 Imidazolderivater

Country Status (15)

Country Link
EP (1) EP0369744B1 (fr)
JP (1) JPH02178283A (fr)
KR (1) KR0161261B1 (fr)
AT (1) ATE111912T1 (fr)
AU (1) AU614680B2 (fr)
CA (1) CA2002834C (fr)
DE (1) DE68918406T2 (fr)
DK (1) DK570689A (fr)
ES (1) ES2064461T3 (fr)
GB (1) GB8826595D0 (fr)
HK (1) HK1004551A1 (fr)
IE (1) IE65585B1 (fr)
NZ (1) NZ231380A (fr)
PT (1) PT92303B (fr)
ZA (1) ZA898678B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8918297D0 (en) * 1989-08-10 1989-09-20 Beecham Group Plc Novel treatment
GB8929208D0 (en) * 1989-12-27 1990-02-28 Almirall Lab New xanthine derivatives
JPH04112889A (ja) * 1990-09-04 1992-04-14 Kyowa Hakko Kogyo Co Ltd Ｋｓ―５０５誘導体
GB9020959D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
US5342841A (en) * 1992-03-12 1994-08-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
GB9312853D0 (en) 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
JP2001523213A (ja) 1994-12-13 2001-11-20 ユーロ−セルティーク，エス．エイ． 三置換チオキサンチン類
DE69531506T2 (de) 1994-12-13 2004-06-24 Euroceltique S.A. Arylthioxanthine
WO1996036638A1 (fr) * 1995-05-19 1996-11-21 Chiroscience Limited Xanthines et leur utilisation therapeutique
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
EP0812844B1 (fr) * 1996-06-07 2002-10-23 Hoechst Aktiengesellschaft Utilisation de dérivés de théophylline pour la prophylaxie et le traitement des conditions de choc, nouveaux composés à base de xanthine et leurs procédés de préparation
US5965555A (en) * 1996-06-07 1999-10-12 Hoechst Aktiengesellschaft Xanthine compounds having terminally animated alkynol side chains
GB9623859D0 (en) * 1996-11-15 1997-01-08 Chiroscience Ltd Novel compounds
GB9703044D0 (en) 1997-02-14 1997-04-02 Glaxo Group Ltd Phenyl xanthine esters and amides
GB9817623D0 (en) 1998-08-13 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608236A5 (fr) * 1974-01-22 1978-12-29 Wuelfing J A Fa
US4061753A (en) * 1976-02-06 1977-12-06 Interx Research Corporation Treating psoriasis with transient pro-drug forms of xanthine derivatives
CA1077932A (fr) * 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Composes de la xanthine pour le traitement des bronchospasmes et des affections allergiques
DE2714953C2 (de) * 1977-04-02 1986-09-25 Hoechst Ag, 6230 Frankfurt Arzneimittel
SE416810C (sv) * 1977-10-14 1982-07-19 Draco Ab Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
CH643260A5 (fr) * 1980-05-02 1984-05-30 Nestle Sa 1-allyl-3-butyl-8-methylxanthine, procede de preparation et utilisation dans un medicament.
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Also Published As

Publication number Publication date
PT92303B (pt) 1995-07-18
EP0369744A3 (fr) 1991-04-10
NZ231380A (en) 1992-12-23
DE68918406D1 (de) 1994-10-27
CA2002834C (fr) 2000-02-22
IE893653L (en) 1990-05-14
DE68918406T2 (de) 1995-03-30
ZA898678B (en) 1990-09-26
AU614680B2 (en) 1991-09-05
EP0369744A2 (fr) 1990-05-23
CA2002834A1 (fr) 1990-05-14
KR0161261B1 (ko) 1998-12-01
JPH02178283A (ja) 1990-07-11
GB8826595D0 (en) 1988-12-21
KR900007842A (ko) 1990-06-02
ATE111912T1 (de) 1994-10-15
DK570689D0 (da) 1989-11-14
HK1004551A1 (en) 1998-11-27
PT92303A (pt) 1990-05-31
IE65585B1 (en) 1995-11-01
ES2064461T3 (es) 1995-02-01
AU4466789A (en) 1990-05-17
EP0369744B1 (fr) 1994-09-21

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment