DK571088A - Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester - Google Patents

Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester

Info

Publication number: DK571088A
Authority: DK; Denmark
Prior art keywords: aspartyl; procedure; preparing alpha; phenylalanine methylester; methylester
Prior art date: 1987-10-13

Application number

DK571088A

Other languages

English (en)

Other versions

DK571088D0 (da

Inventor

Ryuichi Mita

Takeshi Oura

Toshio Katoh

Chojiro Higuchi

Akihiro Yamaguchi

Masanobu Ajioka

Original Assignee

Mitsui Toatsu Chemicals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-13

Filing date

1988-10-13

Publication date

1989-04-14

1988-10-13 Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals

1988-10-13 Publication of DK571088D0 publication Critical patent/DK571088D0/da

1989-04-14 Publication of DK571088A publication Critical patent/DK571088A/da

Links

IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
- C07C5/02—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK571088A 1987-10-13 1988-10-13 Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester DK571088A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP25640687		1987-10-13
JP13841488		1988-06-07

Publications (2)

Publication Number	Publication Date
DK571088D0 DK571088D0 (da)	1988-10-13
DK571088A true DK571088A (da)	1989-04-14

Family

ID=26471445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK571088A DK571088A (da)	1987-10-13	1988-10-13	Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester

Country Status (9)

Country	Link
US (1)	US4897506A (da)
EP (1)	EP0311985B1 (da)
KR (1)	KR910001722B1 (da)
AU (1)	AU600176B2 (da)
BR (1)	BR8805255A (da)
CA (1)	CA1303293C (da)
DE (1)	DE3888781T2 (da)
DK (1)	DK571088A (da)
NO (1)	NO884545L (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5591886A (en) *	1990-11-05	1997-01-07	Mitsui Toatsu Chemicals, Incorporated	Process for the crystallizing L-α-aspartyl-L-phenylalanine methyl ester from the solution
JP2946853B2 (ja) *	1991-05-09	1999-09-06	味の素株式会社	アスパルテームの晶析法
US6238711B1 (en)	1998-11-25	2001-05-29	Wm. Wrigley Jr. Company	Chewing gum with increased flavor release using an aliginate material and method of making

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3786039A (en) *	1969-04-30	1974-01-15	Ajinomoto Kk	Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3761288A (en) *	1970-07-16	1973-09-25	Gen Foods Corp	Method for making a low calorie sweetening composition
US3753739A (en) *	1970-11-05	1973-08-21	Alberto Culver Co	Low calorie dry sweetener composition
US4029701A (en) *	1972-03-30	1977-06-14	General Foods Corporation	Sweetening with hydrohalide salts of dipeptide sweeteners
US3971857A (en) *	1973-11-21	1976-07-27	General Foods Corporation	Multifunctional sweetening composition
US3962468A (en) *	1974-03-07	1976-06-08	General Foods Corporation	Spray-dried L-aspartic acid derivatives
US4465694A (en) *	1980-12-10	1984-08-14	Ajinomoto Company, Incorporated	Dipeptide sweetening composition
US4448716A (en) *	1982-03-04	1984-05-15	G. D. Searle & Co.	Dipeptide sweetener-metal complexes
EP0101756A1 (de) *	1982-08-31	1984-03-07	Chimicasa Gmbh	Wasserlösliche Süssungstablette
JPH0631312B2 (ja) *	1983-03-18	1994-04-27	味の素株式会社	ジペプチド結晶及びその製造方法
JPS59177952A (ja) *	1983-03-28	1984-10-08	Matsushita Electric Ind Co Ltd	樹脂封止電子部品
JPS59227849A (ja) *	1983-06-08	1984-12-21	Ajinomoto Co Inc	Ｌ―α―アスパルチル―Ｌ―フェニルアラニンメチルエステル束状晶の晶析分離法

1988
- 1988-10-05 AU AU23471/88A patent/AU600176B2/en not_active Ceased
- 1988-10-11 KR KR1019880013258A patent/KR910001722B1/ko not_active Expired
- 1988-10-11 DE DE3888781T patent/DE3888781T2/de not_active Expired - Fee Related
- 1988-10-11 EP EP88116875A patent/EP0311985B1/en not_active Expired - Lifetime
- 1988-10-12 BR BR8805255A patent/BR8805255A/pt not_active Application Discontinuation
- 1988-10-12 US US07/256,838 patent/US4897506A/en not_active Expired - Lifetime
- 1988-10-12 NO NO88884545A patent/NO884545L/no unknown
- 1988-10-12 CA CA000580109A patent/CA1303293C/en not_active Expired - Lifetime
- 1988-10-13 DK DK571088A patent/DK571088A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR910001722B1 (ko)	1991-03-22
BR8805255A (pt)	1990-05-29
DK571088D0 (da)	1988-10-13
EP0311985A2 (en)	1989-04-19
AU600176B2 (en)	1990-08-02
NO884545D0 (no)	1988-10-12
DE3888781T2 (de)	1994-10-27
US4897506A (en)	1990-01-30
EP0311985B1 (en)	1994-03-30
AU2347188A (en)	1989-04-13
DE3888781D1 (de)	1994-05-05
EP0311985A3 (en)	1990-08-29
KR890006547A (ko)	1989-06-14
CA1303293C (en)	1992-06-09
NO884545L (no)	1989-04-14

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Legal Events

Date	Code	Title	Description
1988-10-13	A0	Application filed
1993-06-28	AHB	Application shelved due to non-payment