DK572085A - Aromatisk sulfonamid, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents
Aromatisk sulfonamid, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse Download PDFInfo
- Publication number
- DK572085A DK572085A DK572085A DK572085A DK572085A DK 572085 A DK572085 A DK 572085A DK 572085 A DK572085 A DK 572085A DK 572085 A DK572085 A DK 572085A DK 572085 A DK572085 A DK 572085A
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- procedure
- connection
- pharmaceutical preparation
- preparation containing
- Prior art date
Links
- 229940124530 sulfonamide Drugs 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title 1
- -1 Aromatic sulfonamides Chemical class 0.000 abstract 1
- 229940006133 antiglaucoma drug and miotics carbonic anhydrase inhibitors Drugs 0.000 abstract 1
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 abstract 1
- 230000004406 elevated intraocular pressure Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/64—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68068484A | 1984-12-12 | 1984-12-12 | |
| US68068484 | 1984-12-12 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK572085D0 DK572085D0 (da) | 1985-12-11 |
| DK572085A true DK572085A (da) | 1986-06-18 |
| DK167874B1 DK167874B1 (da) | 1993-12-27 |
Family
ID=24732085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK572085A DK167874B1 (da) | 1984-12-12 | 1985-12-11 | Heteroaromatisk sulfonamid, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0189690B1 (da) |
| JP (1) | JPS61158978A (da) |
| AT (1) | ATE41002T1 (da) |
| CA (1) | CA1286294C (da) |
| DE (1) | DE3568431D1 (da) |
| DK (1) | DK167874B1 (da) |
| ES (1) | ES8704498A1 (da) |
| IE (1) | IE59139B1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4863922A (en) * | 1984-12-12 | 1989-09-05 | Merck & Co., Inc. | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use |
| US4894390A (en) * | 1987-08-03 | 1990-01-16 | Merck & Co., Inc. | Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents |
| EP0309028A3 (en) * | 1987-09-16 | 1990-06-27 | Merck & Co. Inc. | Substituted thieno(2,3-b)furan-2-sulfonamides as antiglaucoma agents |
| US4876271A (en) * | 1988-12-20 | 1989-10-24 | Merck & Co., Inc. | Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors |
| US5045561A (en) * | 1990-04-12 | 1991-09-03 | Merck & Co., Inc. | Substituted furan sulfonamides as antiglaucoma agents |
| JPH0830067B2 (ja) * | 1991-10-15 | 1996-03-27 | メルク エンド カムパニー インコーポレーテッド | 三環チエノチオピラン類 |
| ES2118941T3 (es) * | 1992-02-21 | 1998-10-01 | Alcon Lab Inc | Composiciones antiglaucoma topicas que comprenden inhibidores de anhidrasa carbonica y bloqueantes beta. |
| GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| GB9902455D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902453D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| JP4000505B2 (ja) * | 1999-12-01 | 2007-10-31 | 第一三共株式会社 | 緑内障を治療するための併用剤 |
| GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
| NZ580781A (en) * | 2007-05-07 | 2011-11-25 | Cipla Ltd | Process for preparing dorzolamide |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386098A (en) * | 1981-11-03 | 1983-05-31 | Merck & Co., Inc. | 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure |
| US4477466A (en) * | 1983-05-23 | 1984-10-16 | Merck & Co., Inc. | Acyloxy derivatives of [phenylsulfonyl(or sulfinyl)]thiophenesulfonamide for the topical treatment of elevated intraocular pressure |
| US4486444A (en) * | 1983-06-20 | 1984-12-04 | Merck & Co., Inc. | (Hydroxybenzoyl)thiophenesulfonamide and acyl derivatives thereof for the topical treatment of elevated intraocular pressure |
| IL72070A (en) * | 1983-06-20 | 1988-11-30 | Merck & Co Inc | 2-sulfamoylbenzo(b)-thiophene derivatives,their preparation and pharmaceutical compositions containing them |
| US4544667A (en) * | 1984-02-09 | 1985-10-01 | Merck & Co., Inc. | 2-Sulfamoylbenzo[b]furan derivatives for the treatment of elevated intraocular pressure |
| DE3576498D1 (de) * | 1984-03-14 | 1990-04-19 | Merck & Co Inc | 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck. |
-
1985
- 1985-12-10 DE DE8585402452T patent/DE3568431D1/de not_active Expired
- 1985-12-10 AT AT85402452T patent/ATE41002T1/de not_active IP Right Cessation
- 1985-12-10 EP EP85402452A patent/EP0189690B1/en not_active Expired
- 1985-12-11 DK DK572085A patent/DK167874B1/da not_active IP Right Cessation
- 1985-12-11 ES ES549833A patent/ES8704498A1/es not_active Expired
- 1985-12-12 IE IE314385A patent/IE59139B1/en not_active IP Right Cessation
- 1985-12-12 CA CA000497477A patent/CA1286294C/en not_active Expired - Lifetime
- 1985-12-12 JP JP60278093A patent/JPS61158978A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK167874B1 (da) | 1993-12-27 |
| ATE41002T1 (de) | 1989-03-15 |
| DK572085D0 (da) | 1985-12-11 |
| JPS61158978A (ja) | 1986-07-18 |
| EP0189690A1 (en) | 1986-08-06 |
| DE3568431D1 (en) | 1989-04-06 |
| CA1286294C (en) | 1991-07-16 |
| IE59139B1 (en) | 1994-01-12 |
| EP0189690B1 (en) | 1989-03-01 |
| IE853143L (en) | 1986-06-12 |
| ES8704498A1 (es) | 1987-04-01 |
| ES549833A0 (es) | 1987-04-01 |
| JPH0533709B2 (da) | 1993-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |
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