DK572284A - Dna, der indkoder kanintnf, vektor med det deri indsatte dna, vaert transformeret med vektoren, kanintnfpolypeptid og fremgangsmaade til fremstilling af disse - Google Patents

Dna, der indkoder kanintnf, vektor med det deri indsatte dna, vaert transformeret med vektoren, kanintnfpolypeptid og fremgangsmaade til fremstilling af disse Download PDF

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Publication number
DK572284A
DK572284A DK572284A DK572284A DK572284A DK 572284 A DK572284 A DK 572284A DK 572284 A DK572284 A DK 572284A DK 572284 A DK572284 A DK 572284A DK 572284 A DK572284 A DK 572284A
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Prior art keywords
vector
dna
transformed
canetnpolypeptime
canetnf
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DK572284A
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English (en)
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DK572284D0 (da
Inventor
Masaaki Yamada
Yasuji Furutani
Mitsue Notake
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Dainippon Pharmaceutical Co
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Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of DK572284D0 publication Critical patent/DK572284D0/da
Publication of DK572284A publication Critical patent/DK572284A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK572284A 1983-12-02 1984-11-30 Dna, der indkoder kanintnf, vektor med det deri indsatte dna, vaert transformeret med vektoren, kanintnfpolypeptid og fremgangsmaade til fremstilling af disse DK572284A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58228790A JPH0695939B2 (ja) 1983-12-02 1983-12-02 ウサギ癌壊死因子をコ−ドするクロ−ン化ｄνａ

Publications (2)

Publication Number Publication Date
DK572284D0 DK572284D0 (da) 1984-11-30
DK572284A true DK572284A (da) 1985-06-03

Family

ID=16881888

Family Applications (1)

Application Number Title Priority Date Filing Date
DK572284A DK572284A (da) 1983-12-02 1984-11-30 Dna, der indkoder kanintnf, vektor med det deri indsatte dna, vaert transformeret med vektoren, kanintnfpolypeptid og fremgangsmaade til fremstilling af disse

Country Status (10)

Country Link
US (1) US5043271A (da)
EP (1) EP0146026B1 (da)
JP (1) JPH0695939B2 (da)
KR (1) KR920009523B1 (da)
AT (1) ATE60933T1 (da)
AU (1) AU577810B2 (da)
DE (1) DE3484125D1 (da)
DK (1) DK572284A (da)
ES (2) ES8604309A1 (da)
PH (1) PH26947A (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1265444A (en) * 1983-06-27 1990-02-06 Lloyd J. Old Effect of human tumor necrosis factor and human interferon on human cancer cells and methods
JPS60112718A (ja) * 1983-11-21 1985-06-19 Kyorin Pharmaceut Co Ltd 抗腫瘍作用を示す蛋白性物質及びその製造方法
JPS60139624A (ja) * 1983-12-27 1985-07-24 Dainippon Pharmaceut Co Ltd 抗腫瘍作用を有する蛋白質
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide
US6686455B1 (en) 1984-07-05 2004-02-03 Genentech, Inc. Tumor necrosis factor
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
GR851626B (da) * 1984-07-05 1985-11-26 Genentech Inc
EP0216786B1 (en) * 1984-12-21 1992-03-18 Biogen, Inc. Purification, production and use of tumor necrosis factors
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
US5843693A (en) * 1989-08-16 1998-12-01 Chiron Corporation Assay method for screening for inhibitors of proTNF conversion
US6586222B1 (en) 1989-08-16 2003-07-01 Chiron Corporation Recombinant PR-3 and compositions thereof
ATE148992T1 (de) 1989-08-16 1997-03-15 Chiron Corp Zusammensetzungen zur hemmung der bildung von proteinhormon und deren verwendungen
US5998378A (en) * 1989-08-16 1999-12-07 Chiron Corporation Compositions for the inhibition of TNF hormone formation and uses thereof
WO1991017180A1 (en) * 1990-04-27 1991-11-14 Peptide Technology Ltd Peptides derived from human tumour necrosis factor alpha and useful against intracellular malarial parasites
US5653974A (en) * 1990-10-18 1997-08-05 Board Of Regents,The University Of Texas System Preparation and characterization of liposomal formulations of tumor necrosis factor
CA2185162A1 (en) 1994-03-07 1995-09-14 Robert F. Halenback (Deceased) Compositions for the inhibition of tnf formation and uses thereof
DE60333228D1 (de) 2002-12-02 2010-08-12 Amgen Fremont Inc Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57140725A (en) * 1981-12-28 1982-08-31 Dainippon Pharmaceut Co Ltd Physiologically active substance having carcinostatic action
JPS6019719A (ja) * 1983-07-15 1985-01-31 Asahi Chem Ind Co Ltd 抗腫瘍活性を有する蛋白質
EP0148311B1 (en) * 1983-12-26 1988-07-20 Asahi Kasei Kogyo Kabushiki Kaisha A novel physiologically active polypeptide
DE19975063I2 (de) * 1984-03-06 2005-08-18 Dainippon Pharmaceutical Co DNS den menschlichen Tumornekrosisfaktor kodierendund das menschliche Tumornekronisfaktor-Polypepti d.
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide

Also Published As

Publication number Publication date
ES538000A0 (es) 1986-01-16
KR850004272A (ko) 1985-07-11
KR920009523B1 (ko) 1992-10-17
AU577810B2 (en) 1988-10-06
DE3484125D1 (de) 1991-03-28
EP0146026A2 (en) 1985-06-26
JPS60120990A (ja) 1985-06-28
JPH0695939B2 (ja) 1994-11-30
ES8604309A1 (es) 1986-01-16
PH26947A (en) 1992-12-03
EP0146026A3 (en) 1987-05-20
US5043271A (en) 1991-08-27
ES8605578A1 (es) 1986-03-16
ES547436A0 (es) 1986-03-16
ATE60933T1 (de) 1991-03-15
AU3601484A (en) 1985-06-06
DK572284D0 (da) 1984-11-30
EP0146026B1 (en) 1991-02-20

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