DK586186A - Usymmetriske alfa-hydroxythioethere samt deres fremstilling og anvendelse - Google Patents

Usymmetriske alfa-hydroxythioethere samt deres fremstilling og anvendelse

Info

Publication number: DK586186A
Authority: DK; Denmark
Prior art keywords: single bond; group; optionally; phenylene; ethylene
Prior art date: 1985-12-06

Application number

DK586186A

Other languages

English (en)

Other versions

DK586186D0 (da

Inventor

Andreas Beck

Werner Breitenstein

Andreas Von Sprecher

Robert W Lang

Konrad Oertle

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-06

Filing date

1986-12-05

Publication date

1987-06-07

1986-12-05 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1986-12-05 Publication of DK586186D0 publication Critical patent/DK586186D0/da

1987-06-07 Publication of DK586186A publication Critical patent/DK586186A/da

Links

VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 2
239000005977 Ethylene Substances 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000000172 allergic effect Effects 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000006295 amino methylene group Chemical group [H]N(*)C([H])([H])* 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
230000008602 contraction Effects 0.000 abstract 1
125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
125000005677 ethinylene group Chemical group [*:2]C#C[*:1] 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002460 smooth muscle Anatomy 0.000 abstract 1
150000003568 thioethers Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Emergency Medicine (AREA)
Pulmonology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)

DK586186A 1985-12-06 1986-12-05 Usymmetriske alfa-hydroxythioethere samt deres fremstilling og anvendelse DK586186A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH522885		1985-12-06

Publications (2)

Publication Number	Publication Date
DK586186D0 DK586186D0 (da)	1986-12-05
DK586186A true DK586186A (da)	1987-06-07

Family

ID=4290092

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK586186A DK586186A (da)	1985-12-06	1986-12-05	Usymmetriske alfa-hydroxythioethere samt deres fremstilling og anvendelse

Country Status (17)

Country	Link
US (1)	US4808572A (da)
EP (1)	EP0225602B1 (da)
JP (1)	JPS62138465A (da)
AT (1)	ATE68177T1 (da)
AU (1)	AU6613886A (da)
CA (1)	CA1303294C (da)
DD (1)	DD260494A5 (da)
DE (1)	DE3681890D1 (da)
DK (1)	DK586186A (da)
ES (1)	ES2040205T3 (da)
FI (1)	FI864901A7 (da)
GR (1)	GR3003066T3 (da)
HU (1)	HU196173B (da)
IL (1)	IL80866A0 (da)
NO (1)	NO864896L (da)
PT (1)	PT83868B (da)
ZA (1)	ZA869213B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5149717A (en) *	1988-03-29	1992-09-22	Ciba-Geigy Corporation	Alkanophenones useful for treating allergies
FR2648814B1 (fr) *	1989-06-26	1991-10-18	Lafon Labor	L'alpha (tert-butyl-aminomethyl-3,4-dichlorobenzyl)thioacetamide, son procede de preparation et son application en therapeutique
EP0419410A3 (en) *	1989-09-19	1991-08-14	Ciba-Geigy Ag	Alkanophenones
DE59410387D1 (de) *	1993-01-29	2004-10-21	Ticona Gmbh	Faserverstärktes Cycloolefincopolymer-Material, Verfahren zu seiner Herstellung und Formkörper aus dem Material
JP2007510672A (ja) *	2003-11-13	2007-04-26	ザ・ユニバーシティ・オブ・シドニー	ビス−陽イオン化合物およびそれらの使用
WO2007022718A1 (fr) *	2005-08-25	2007-03-01	Chunde Liu	Alcools alkylaryle, leurs derives et leur procede de preparation
PL2632889T3 (pl) *	2010-10-28	2019-04-30	Mapi Pharma Ltd	Związki pośrednie i sposób wytwarzania fingolimodu
CN102850319A (zh) *	2011-06-27	2013-01-02	中国药科大学	一种制备{5-[2-(4-正辛基苯基)乙基]-2,2-二甲基-1,3-二氧六环-5-基}氨基甲酸叔丁酯的方法
US20240209140A1 (en) *	2021-04-28	2024-06-27	Basf Coatings Gmbh	Hydroxyl-functional thioether compounds and their use in curable compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3262587D1 (en) *	1981-03-03	1985-04-25	Lilly Industries Ltd	Leukotriene analogues, their preparation and use in pharmaceutical compositions
US4513005A (en) *	1981-06-18	1985-04-23	Lilly Industries Limited	SRS-A antagonists
US4461775A (en) *	1982-08-02	1984-07-24	Mcneilab, Inc.	Hydroxythioether fatty acid derivatives
US4552893A (en) *	1983-03-07	1985-11-12	Smithkline Beckman Corporation	Leukotriene antagonists
US4533747A (en) *	1983-03-07	1985-08-06	Smithkline Beckman Corporation	Leukotriene antagonists intermediates
DK130984A (da) *	1983-03-07	1984-09-08	Smithkline Beckman Corp	Leukotrien-antagonister
EP0123543B1 (en) *	1983-04-21	1988-02-03	Merck Frosst Canada Inc.	Leukotriene antagonists, their production and use and compositions containing them
US4649215A (en) *	1984-06-28	1987-03-10	Ciba-Geigy Corporation	Aliphatic thioethers

1986
- 1986-12-01 US US06/936,671 patent/US4808572A/en not_active Expired - Fee Related
- 1986-12-01 FI FI864901A patent/FI864901A7/fi not_active IP Right Cessation
- 1986-12-03 EP EP86116810A patent/EP0225602B1/de not_active Expired - Lifetime
- 1986-12-03 AT AT86116810T patent/ATE68177T1/de active
- 1986-12-03 ES ES198686116810T patent/ES2040205T3/es not_active Expired - Lifetime
- 1986-12-03 DE DE8686116810T patent/DE3681890D1/de not_active Expired - Lifetime
- 1986-12-04 PT PT83868A patent/PT83868B/pt not_active IP Right Cessation
- 1986-12-04 IL IL80866A patent/IL80866A0/xx unknown
- 1986-12-04 CA CA000524509A patent/CA1303294C/en not_active Expired - Lifetime
- 1986-12-04 DD DD86297075A patent/DD260494A5/de unknown
- 1986-12-05 AU AU66138/86A patent/AU6613886A/en not_active Abandoned
- 1986-12-05 JP JP61289067A patent/JPS62138465A/ja active Pending
- 1986-12-05 DK DK586186A patent/DK586186A/da not_active Application Discontinuation
- 1986-12-05 ZA ZA869213A patent/ZA869213B/xx unknown
- 1986-12-05 HU HU865040A patent/HU196173B/hu not_active IP Right Cessation
- 1986-12-05 NO NO864896A patent/NO864896L/no unknown
1991
- 1991-11-06 GR GR91401392T patent/GR3003066T3/el unknown

Also Published As

Publication number	Publication date
EP0225602A3 (en)	1989-06-14
FI864901A7 (fi)	1987-06-07
EP0225602A2 (de)	1987-06-16
HU196173B (en)	1988-10-28
PT83868A (en)	1987-01-01
NO864896L (no)	1987-06-09
EP0225602B1 (de)	1991-10-09
DD260494A5 (de)	1988-09-28
ZA869213B (en)	1987-07-29
JPS62138465A (ja)	1987-06-22
GR3003066T3 (en)	1993-02-17
ATE68177T1 (de)	1991-10-15
PT83868B (pt)	1989-07-31
NO864896D0 (no)	1986-12-05
US4808572A (en)	1989-02-28
HUT43560A (en)	1987-11-30
DK586186D0 (da)	1986-12-05
FI864901A0 (fi)	1986-12-01
AU6613886A (en)	1987-06-11
ES2040205T3 (es)	1993-10-16
IL80866A0 (en)	1987-03-31
CA1303294C (en)	1992-06-09
DE3681890D1 (en)	1991-11-14

Legal Events

Date	Code	Title	Description
1993-08-30	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK624286A (da)	1987-06-24	Usymmetriske aromatiske alfa-hydroxythioethere og salte deraf samt deres fremstilling og anvendelse
GR850126B (da)	1985-05-16
SE8302130D0 (sv)	1983-04-15	Farmakologiskt aktiva bifosfonater, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma
IE822322L (en)	1983-03-26	Vicinal dihydroxyalkylxanthines
DK586186A (da)	1987-06-07	Usymmetriske alfa-hydroxythioethere samt deres fremstilling og anvendelse
IL69292A (en)	1987-03-31	Muramyl peptides substituted by 1,2-diacylated-sn-glycero-3-hydroxyphosphoryl,their manufacture and pharmaceutical compositions containing them
IL69036A (en)	1986-01-31	Alpha-alkyl undecapentaenoic acids,pharmaceutical compositions containing the same and processes for the preparation thereof
ES519532A0 (es)	1984-03-16	Procedimiento de preparacion de derivados de imidazolidina.
IL69056A (en)	1987-12-31	Method of treating non-human mammals with cyclic ketenedithioacetal derivatives,pharmaceutical compositions containing them,certain new such compounds and their preparation
SE8306112D0 (sv)	1983-11-07	Neue biologisch aktive peptide
SE8302084L (sv)	1983-10-16	Nya bensimidazolderivat
ES544709A0 (es)	1986-01-16	Procedimiento para la obtencion de iminosulfonamidas
GB2001066A (en)	1979-01-24	Preparation of benzylidene derivatives