DK602084A - Fremgangsmaade til adskillelse af racemiske blandinger af bicycliske imino-alfa-carboxylsyreestere samt diastereomert salt af en saadan ester - Google Patents

Fremgangsmaade til adskillelse af racemiske blandinger af bicycliske imino-alfa-carboxylsyreestere samt diastereomert salt af en saadan ester Download PDF

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Publication number
DK602084A
DK602084A DK602084A DK602084A DK602084A DK 602084 A DK602084 A DK 602084A DK 602084 A DK602084 A DK 602084A DK 602084 A DK602084 A DK 602084A DK 602084 A DK602084 A DK 602084A
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DK
Denmark
Prior art keywords
salts
ester
carboxylic acid
acid esters
racemic mixtures
Prior art date
Application number
DK602084A
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English (en)
Other versions
DK163819B (da
DK602084D0 (da
DK163819C (da
Inventor
Ulrich Lerch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK602084D0 publication Critical patent/DK602084D0/da
Publication of DK602084A publication Critical patent/DK602084A/da
Publication of DK163819B publication Critical patent/DK163819B/da
Application granted granted Critical
Publication of DK163819C publication Critical patent/DK163819C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK602084A 1983-12-15 1984-12-14 Fremgangsmaade til adskillelse af racemiske blandinger af bicycliske imino-alfa-carboxylsyreestere DK163819C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833345355 DE3345355A1 (de) 1983-12-15 1983-12-15 Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester
DE3345355 1983-12-15

Publications (4)

Publication Number Publication Date
DK602084D0 DK602084D0 (da) 1984-12-14
DK602084A true DK602084A (da) 1985-06-16
DK163819B DK163819B (da) 1992-04-06
DK163819C DK163819C (da) 1992-09-07

Family

ID=6216990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK602084A DK163819C (da) 1983-12-15 1984-12-14 Fremgangsmaade til adskillelse af racemiske blandinger af bicycliske imino-alfa-carboxylsyreestere

Country Status (15)

Country Link
US (1) US4659838A (da)
EP (1) EP0146080B1 (da)
JP (2) JPH062734B2 (da)
KR (1) KR910009935B1 (da)
AT (1) ATE44953T1 (da)
CA (1) CA1232910A (da)
DE (2) DE3345355A1 (da)
DK (1) DK163819C (da)
ES (1) ES538556A0 (da)
FI (1) FI81783C (da)
GR (1) GR82456B (da)
HU (1) HU195952B (da)
IE (1) IE57752B1 (da)
IL (1) IL73822A (da)
PT (1) PT79669B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
GB0216416D0 (en) * 2002-07-15 2002-08-21 Novartis Ag Organic compounds
MXPA05011168A (es) * 2003-04-15 2005-12-14 Warner Lambert Co Derivados de prolina biciclicos [b]-condensados y sus usos para tratar afecciones artriticas.
CA2521364A1 (en) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc [c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
MX2008008350A (es) * 2005-12-22 2008-09-03 Schering Corp Procedimiento para la preparacion de compuestos 6,6-dimetil-3-azabiciclo-[3.1.0]-hexano y sales enantiomericas del mismo.
WO2007147480A2 (en) * 2006-06-19 2007-12-27 Merck Patent Gmbh Polymorphic forms and process
ES2686298T3 (es) * 2010-04-20 2018-10-17 Chiral Quest, Inc. Procedimiento enantioselectivo para alaninas beta sustituidas con cicloalquenilo

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880866A (en) * 1972-05-01 1975-04-29 American Home Prod 7-Azaindole fused heterocyclic compounds
JPS50101355A (da) * 1974-01-17 1975-08-11
SU573480A1 (ru) * 1976-01-12 1977-09-25 Предприятие П/Я М-5043 Способ получени -пролина
JPS5346967A (en) * 1976-10-08 1978-04-27 Kyowa Hakko Kogyo Co Ltd R-2-(beta-halogenoethyl)-1-methyl-pyrrolidine
US4111951A (en) * 1977-01-17 1978-09-05 Hoffmann-La Roche Inc. Process for L-3,4-dehydroproline
YU93877A (en) * 1977-04-08 1982-06-30 Krka Process for the resolution of racemic alpha-aminonitrils
CA1117127A (en) * 1978-06-27 1982-01-26 Janet A. Day Derivatives of 3-azabicyclo(3.1.0)hexane and a process for their preparation
ZA811493B (en) * 1980-04-02 1982-03-31 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
HU191120B (en) * 1983-01-31 1987-01-28 Hoechts Ag,De Process for raceme separation of optically active byciclic imino-alpha-carbonic acid esthers

Also Published As

Publication number Publication date
ES8601884A1 (es) 1985-11-01
HUT39427A (en) 1986-09-29
HU195952B (en) 1988-08-29
GR82456B (en) 1985-04-08
DK163819B (da) 1992-04-06
JPS60146871A (ja) 1985-08-02
FI844929L (fi) 1985-06-16
DE3345355A1 (de) 1985-06-27
EP0146080A3 (en) 1985-08-07
IE57752B1 (en) 1993-03-24
IL73822A0 (en) 1985-03-31
EP0146080A2 (de) 1985-06-26
ES538556A0 (es) 1985-11-01
IE843222L (en) 1985-06-15
DK602084D0 (da) 1984-12-14
DE3479118D1 (en) 1989-08-31
ATE44953T1 (de) 1989-08-15
JPH0723359B2 (ja) 1995-03-15
PT79669B (de) 1986-11-24
KR910009935B1 (ko) 1991-12-06
US4659838A (en) 1987-04-21
DK163819C (da) 1992-09-07
FI81783B (fi) 1990-08-31
IL73822A (en) 1989-02-28
FI81783C (fi) 1990-12-10
EP0146080B1 (de) 1989-07-26
KR850004461A (ko) 1985-07-15
PT79669A (de) 1985-01-01
JPH062734B2 (ja) 1994-01-12
JPH06312977A (ja) 1994-11-08
FI844929A0 (fi) 1984-12-13
CA1232910A (en) 1988-02-16

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