DK618389A - Pyrrolderivater - Google Patents

Pyrrolderivater Download PDF

Info

Publication number: DK618389A
Authority: DK; Denmark
Prior art keywords: alkyl; optionally substituted; phenyl; cycloalkyl; hydrogen
Prior art date: 1988-12-09

Application number

DK618389A

Other languages

English (en)

Other versions

DK618389D0 (da

Inventor

Ian Thomson Forbes

Roger Thomas Martin

Mervyn Thompson

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-09

Filing date

1989-12-07

Publication date

1990-06-10

1989-12-07 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1989-12-07 Publication of DK618389D0 publication Critical patent/DK618389D0/da

1990-06-10 Publication of DK618389A publication Critical patent/DK618389A/da

Links

KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 9
-1 nitro, amino Chemical group 0.000 abstract 8
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 7
229910052739 hydrogen Inorganic materials 0.000 abstract 6
239000001257 hydrogen Substances 0.000 abstract 6
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 5
125000001589 carboacyl group Chemical group 0.000 abstract 5
229910052736 halogen Inorganic materials 0.000 abstract 5
150000002367 halogens Chemical class 0.000 abstract 5
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 4
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 3
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 2
125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 2
125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
125000006619 (C1-C6) dialkylamino group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Photoreceptors In Electrophotography (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Mechanical Treatment Of Semiconductor (AREA)
Pyrrole Compounds (AREA)

DK618389A 1988-12-09 1989-12-07 Pyrrolderivater DK618389A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888828806A GB8828806D0 (en)	1988-12-09	1988-12-09	Novel compounds

Publications (2)

Publication Number	Publication Date
DK618389D0 DK618389D0 (da)	1989-12-07
DK618389A true DK618389A (da)	1990-06-10

Family

ID=10648253

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK618389A DK618389A (da)	1988-12-09	1989-12-07	Pyrrolderivater

Country Status (12)

Country	Link
US (1)	US5079246A (da)
EP (1)	EP0372962B1 (da)
JP (1)	JPH02184687A (da)
AT (1)	ATE108792T1 (da)
AU (1)	AU629578B2 (da)
CA (1)	CA2004893A1 (da)
DE (1)	DE68916918T2 (da)
DK (1)	DK618389A (da)
GB (1)	GB8828806D0 (da)
NZ (1)	NZ231667A (da)
PT (1)	PT92524B (da)
ZA (1)	ZA899356B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW313589B (da) *	1991-12-12	1997-08-21	Wacker Chemie Gmbh
US5856148A (en) *	1991-12-12	1999-01-05	Wacker Chemie Gmbh	Materials and methods for biosynthesis of serine and serine-related products
GB9309179D0 (en) *	1993-05-05	1993-06-16	Smithkline Beecham Plc	New use
NZ522074A (en)	2000-05-31	2004-06-25	Astrazeneca Ab	Indole derivatives with vascular damaging activity
US6956035B2 (en) *	2001-08-31	2005-10-18	Inotek Pharmaceuticals Corporation	Isoquinoline derivatives and methods of use thereof
US20030096833A1 (en) *	2001-08-31	2003-05-22	Jagtap Prakash G.	Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
WO2003082271A2 (en)	2002-04-03	2003-10-09	Astrazeneca Ab	Indole derivatives having anti-angiogenetic activity
AU2004258801A1 (en) *	2003-02-28	2005-02-03	Inotek Pharmaceuticals Corporation	Tetracyclic Benzamide Derivatives and methods of use thereof
RU2006134024A (ru) *	2004-02-26	2008-04-10	Инотек Фармасьютикалз Корпорейшн (Us)	Тетрациклические производные лактама и их использование
WO2005082368A1 (en) *	2004-02-26	2005-09-09	Inotek Pharmaceuticals Corporation	Isoquinoline derivatives and methods of use thereof
EP1784186A4 (en) *	2004-06-16	2008-05-14	Inotek Pharmaceuticals Corp	METHOD FOR TREATING AND PREVENTING EFFECTS AND ENTIRE INCONTINENCE
EP1855676A4 (en) *	2005-02-25	2008-05-21	Inotek Pharmaceuticals Corp	TETRAZYCLIC AMINO AND CARBOXAMIDE COMPOUNDS AND METHOD FOR THEIR USE
KR20070116016A (ko) *	2005-02-25	2007-12-06	이노텍 파마슈티컬스 코포레이션	이소퀴놀린 화합물 및 그의 이용 방법
US20060287311A1 (en) *	2005-02-25	2006-12-21	Inotek Pharmaceuticals Corporation	Tetracyclic Sulfonamide Compounds and methods of use thereof
AU2006283078A1 (en) *	2005-08-24	2007-03-01	Inotek Pharmaceuticals Corporation	Indenoisoquinolinone Analogs and methods of use thereof
US8119654B2 (en) *	2007-02-28	2012-02-21	Inotek Pharmaceuticals Corporation	Indenoisoquinolinone analogs and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8600651D0 (en) *	1986-01-11	1986-02-19	Beecham Group Plc	Compounds
GB8610980D0 (en) *	1986-05-06	1986-06-11	Ici America Inc	Heterocyclic fused tricyclic compounds

1988
- 1988-12-09 GB GB888828806A patent/GB8828806D0/en active Pending
1989
- 1989-12-07 US US07/447,212 patent/US5079246A/en not_active Expired - Fee Related
- 1989-12-07 AU AU45960/89A patent/AU629578B2/en not_active Ceased
- 1989-12-07 PT PT92524A patent/PT92524B/pt not_active IP Right Cessation
- 1989-12-07 AT AT89312771T patent/ATE108792T1/de active
- 1989-12-07 ZA ZA899356A patent/ZA899356B/xx unknown
- 1989-12-07 NZ NZ231667A patent/NZ231667A/en unknown
- 1989-12-07 CA CA002004893A patent/CA2004893A1/en not_active Abandoned
- 1989-12-07 EP EP89312771A patent/EP0372962B1/en not_active Expired - Lifetime
- 1989-12-07 DK DK618389A patent/DK618389A/da not_active Application Discontinuation
- 1989-12-07 DE DE68916918T patent/DE68916918T2/de not_active Expired - Fee Related
- 1989-12-09 JP JP1320365A patent/JPH02184687A/ja active Pending

Also Published As

Publication number	Publication date
DE68916918T2 (de)	1994-11-03
DE68916918D1 (de)	1994-08-25
ZA899356B (en)	1990-10-31
DK618389D0 (da)	1989-12-07
ATE108792T1 (de)	1994-08-15
PT92524B (pt)	1995-08-09
EP0372962A2 (en)	1990-06-13
EP0372962B1 (en)	1994-07-20
GB8828806D0 (en)	1989-01-18
AU4596089A (en)	1990-06-14
EP0372962A3 (en)	1991-07-31
CA2004893A1 (en)	1990-06-09
JPH02184687A (ja)	1990-07-19
US5079246A (en)	1992-01-07
AU629578B2 (en)	1992-10-08
NZ231667A (en)	1992-11-25
PT92524A (pt)	1990-06-29

Legal Events

Date	Code	Title	Description
1994-08-22	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK618389A (da)	1990-06-10	Pyrrolderivater
ATE247654T1 (de)	2003-09-15	Neue heterozyklische verbindungen
DE69009646D1 (de)	1994-07-14	Substituierte Harnstoffverbindungen, ihre Herstellung und Verwendung.
HUT56809A (en)	1991-10-28	Herbicidal composition comprising 2-(2', 3', 4'-trisubstituted benzoyl)-1,3-cyclohexanedione derivatives as active ingredient
DE69220048D1 (de)	1997-07-03	Imidazoacridine und ihre antineoplastische anwendung
DK26689D0 (da)	1989-01-20	Hidtil ukendte forbindelser
AU6831690A (en)	1991-07-11	Fungicides
DK544689A (da)	1990-05-05	Forbindelser til behandling af urininkontinens
DE3771652D1 (de)	1991-08-29	Indolo-pyrazino-benzodiazepin-derivate.
DK411989D0 (da)	1989-08-22	7-(6-amino-2-azabicyclooe2.2.2aaoct-yl)-1,4-dihydro -6-fluor-4-oxo-3-quinolincarboxylsyre-forbindelser, farmaceutiske praeparater indeholdende disse og anvendelse af forbindelserne til fremstilling af antibakterielle laegemidler