DK62187D0 - Farmaceutisk praeparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf - Google Patents

Farmaceutisk praeparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf

Info

Publication number: DK62187D0
Authority: DK; Denmark
Prior art keywords: pregnan; hydroxy; 3alfa; 5beta; preparing
Prior art date: 1986-02-13

Application number

DK062187A

Other languages

English (en)

Other versions

DK175504B1 (da

DK62187A (da

Inventor

Roland Ingolf Jeppsson

Original Assignee

Kabivitrum Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-02-13

Filing date

1987-02-06

Publication date

1987-02-06

1987-02-06 Application filed by Kabivitrum Ab filed Critical Kabivitrum Ab

1987-02-06 Publication of DK62187D0 publication Critical patent/DK62187D0/da

1987-08-14 Publication of DK62187A publication Critical patent/DK62187A/da

2004-11-15 Application granted granted Critical

2004-11-15 Publication of DK175504B1 publication Critical patent/DK175504B1/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
AURFZBICLPNKBZ-YZRLXODZSA-N 3alpha-hydroxy-5beta-pregnan-20-one Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1 AURFZBICLPNKBZ-YZRLXODZSA-N 0.000 abstract 2
AURFZBICLPNKBZ-UHFFFAOYSA-N Pregnanolone Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 AURFZBICLPNKBZ-UHFFFAOYSA-N 0.000 abstract 2
229950007402 eltanolone Drugs 0.000 abstract 2
238000001990 intravenous administration Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000007764 o/w emulsion Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Anesthesiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Plural Heterocyclic Compounds (AREA)

DK198700621A 1986-02-13 1987-02-06 Farmaceutisk præparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf DK175504B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8600632		1986-02-13
SE8600632A SE8600632D0 (sv)	1986-02-13	1986-02-13	Novel pharmaceutical composition

Publications (3)

Publication Number	Publication Date
DK62187D0 true DK62187D0 (da)	1987-02-06
DK62187A DK62187A (da)	1987-08-14
DK175504B1 DK175504B1 (da)	2004-11-15

Family

ID=20363448

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198700621A DK175504B1 (da)	1986-02-13	1987-02-06	Farmaceutisk præparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf

Country Status (14)

Country	Link
US (1)	US5028600A (da)
EP (1)	EP0233849B1 (da)
JP (1)	JPH0788305B2 (da)
AT (1)	ATE64526T1 (da)
CA (1)	CA1301651C (da)
DE (1)	DE3770830D1 (da)
DK (1)	DK175504B1 (da)
ES (1)	ES2037742T3 (da)
FI (1)	FI88676C (da)
GR (1)	GR3002299T3 (da)
HK (1)	HK83293A (da)
NO (1)	NO175040B (da)
SE (1)	SE8600632D0 (da)
SG (1)	SG102892G (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9302295D0 (sv) *	1993-07-02	1993-07-02	Kabi Pharmacia Ab	New pharmaceutical composition
US5616330A (en) *	1994-07-19	1997-04-01	Hemagen/Pfc	Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
US6117429A (en) *	1997-08-11	2000-09-12	Weider Nutrition International, Inc	Compositions and treatments for reducing potential unwanted side effects associated with long-term administration of androgenic testosterone precursors
ES2211151T3 (es)	1998-08-19	2004-07-01	Skyepharma Canada Inc.	Dispersiones acuosas inyectables de propofol.
WO2002053102A2 (en) *	2000-12-29	2002-07-11	The Trustees Of Columbia University In The City Of New York	Use of iv emulsions with different triglyceride composition, particle size and apolipoprotein e for targeted tissue delivery of hydrophobic compounds
BRPI0312377A8 (pt) *	2002-07-02	2015-12-15	Altana Pharma Ag	Suspensão aquosa estéril contendo ciclesonida
PE20050941A1 (es)	2003-12-16	2005-11-08	Nycomed Gmbh	Suspensiones acuosas de ciclesonida para nebulizacion
AU2005283726A1 (en) *	2004-09-13	2006-03-23	Bharat Serums & Vaccines Ltd.	Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
CN103491976B (zh) *	2011-01-14	2015-04-01	卡思伯特·O·辛普金斯	用于处理与缺乏血液供给、休克和神经损伤相关的疾病的方法和组合物
US10478505B2 (en)	2011-09-23	2019-11-19	The Regents Of The University Of California	Edible oils to enhance delivery of orally administered steroids
SG10201606063RA (en)	2012-01-23	2016-09-29	Sage Therapeutics Inc	Neuroactive steroid formulations and methods of treating cns disorders
US20140050789A1 (en)	2012-08-13	2014-02-20	The Regents Of The University Of California	Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
MX2015002252A (es)	2012-08-21	2015-07-21	Sage Therapeutics Inc	Metodos para tratar epilepsia o estado de epilepsia.
DK2925327T3 (da)	2012-11-30	2024-03-25	Univ California	Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression
JOP20200195A1 (ar)	2014-09-08	2017-06-16	Sage Therapeutics Inc	سترويدات وتركيبات نشطة عصبياً، واستخداماتها
HK1258616A1 (zh)	2016-03-08	2019-11-15	Sage Therapeutics, Inc.	神经活性类固醇、组合物、及其用途
WO2020123551A1 (en) *	2018-12-10	2020-06-18	Halo Science LLC	Stable formulations of anesthetics and associated dosage forms
CA3151334C (en) *	2019-08-19	2024-04-09	Arizona Board Of Regents On Behalf Of The University Of Arizona	Topical neurosteroid formulations
US11969434B1 (en)	2022-08-29	2024-04-30	Lipocine Inc.	Oral allopregnanolone compositions and methods of use
CN114344309B (zh) *	2021-12-30	2024-02-06	南京迈诺威医药科技有限公司	一种别孕烷醇酮衍生物自乳化制剂及其制备方法
US12186327B2 (en)	2022-08-29	2025-01-07	Lipocine Inc.	Oral allopregnanolone compositions and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1215702B (de) *	1962-07-03	1966-05-05	Merck Ag E	Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) *	1969-11-05	1972-03-21	Kruger Gunther	PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3917830A (en) *	1970-12-17	1975-11-04	Glaxo Lab Ltd	Steroidal anaesthetic composition for intraveneous injection
US3900561A (en) *	1970-12-17	1975-08-19	Glaxo Lab Ltd	Pharmaceutical compositions
US4168308A (en) *	1976-03-12	1979-09-18	Apoteksvarucentralen Vitrum Ab	Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) *	1980-05-15	1985-03-12	株式会社ミドリ十字	ステロイド製剤
JPS5716818A (en) *	1981-04-25	1982-01-28	Green Cross Corp:The	Steroid fatty emulsion
JPS60258110A (ja) *	1984-06-05	1985-12-20	Daigo Eiyou Kagaku Kk	静脈注射可能なプロゲステロン乳化注射液

1986
- 1986-02-13 SE SE8600632A patent/SE8600632D0/xx unknown
1987
- 1987-01-29 DE DE8787850029T patent/DE3770830D1/de not_active Expired - Fee Related
- 1987-01-29 EP EP87850029A patent/EP0233849B1/en not_active Expired - Lifetime
- 1987-01-29 AT AT87850029T patent/ATE64526T1/de not_active IP Right Cessation
- 1987-01-29 ES ES198787850029T patent/ES2037742T3/es not_active Expired - Lifetime
- 1987-02-06 DK DK198700621A patent/DK175504B1/da not_active IP Right Cessation
- 1987-02-12 JP JP62028395A patent/JPH0788305B2/ja not_active Expired - Fee Related
- 1987-02-12 CA CA000529609A patent/CA1301651C/en not_active Expired - Fee Related
- 1987-02-12 FI FI870589A patent/FI88676C/fi not_active IP Right Cessation
- 1987-02-12 NO NO870560A patent/NO175040B/no not_active IP Right Cessation
1989
- 1989-02-28 US US07/316,576 patent/US5028600A/en not_active Expired - Lifetime
1991
- 1991-07-11 GR GR91400996T patent/GR3002299T3/el unknown
1992
- 1992-10-07 SG SG1028/92A patent/SG102892G/en unknown
1993
- 1993-08-12 HK HK832/93A patent/HK83293A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK175504B1 (da)	2004-11-15
EP0233849B1 (en)	1991-06-19
EP0233849A1 (en)	1987-08-26
FI88676C (fi)	1993-06-28
CA1301651C (en)	1992-05-26
FI870589A0 (fi)	1987-02-12
US5028600A (en)	1991-07-02
NO175040C (da)	1994-08-24
NO870560D0 (no)	1987-02-12
JPS62192322A (ja)	1987-08-22
FI88676B (fi)	1993-03-15
GR3002299T3 (en)	1992-12-30
HK83293A (en)	1993-08-20
DK62187A (da)	1987-08-14
FI870589L (fi)	1987-08-14
ATE64526T1 (de)	1991-07-15
ES2037742T3 (es)	1993-07-01
DE3770830D1 (de)	1991-07-25
NO175040B (no)	1994-05-16
NO870560L (no)	1987-08-14
JPH0788305B2 (ja)	1995-09-27
SG102892G (en)	1992-12-04
SE8600632D0 (sv)	1986-02-13

Legal Events

Date	Code	Title	Description
2005-10-03	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK62187D0 (da)	1987-02-06	Farmaceutisk praeparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf
DK365488A (da)	1988-07-01	Nye bensimidazolderivater, fremgangsmaade til fremstilling deraf og et farmaceutisk praeparat indeholdende dem
EP0221041A3 (en)	1987-10-28	Benzimidazole derivatives, process for their preparation and their pharmaceutical use
GR1001503B (el)	1994-02-28	Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών.
DE69132688D1 (de)	2001-09-20	Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
HUT52040A (en)	1990-06-28	Process for producing diaryl-derivatives and pharmaceutical compositions containing them
HU901095D0 (en)	1991-09-30	Process for producing compound reducing extraction of gastric acid and pharmaceutical preparative containing said compound
IT1228437B (it)	1991-06-17	"derivati di 2,3,4,5,6,7 esaidro 2,7-metano-1,5 benzossazonina (rispettivamente 1,4 benzossazonina), procedimento per la loro preparazione e prodotti medicinali che contengono questi composti.
AT342761B (de)	1978-04-25	Verfahren zur herstellung von homopyrimidazol-derivate enthaltenden, stabilen pharmazeutischen praparaten zur oralen verabreichung
ES8704487A1 (es)	1987-04-16	Procedimiento para preparar derivados de 3,4-diazol
ES8303324A1 (es)	1983-02-01	"procedimiento para preparar una sustancia activa adecuada para la estabilizacion de prostaglandinas y sus derivados".
ATE105570T1 (de)	1994-05-15	Modifizierte menschliche anti-rh(d)-antikoerper.
KR930012025A (ko)	1993-07-20	한방성 b형 간염치료제
SE8704049D0 (sv)	1987-10-16	Novel pharmacological compounds
JO1519B1 (en)	1989-01-25	New compounds (new benzimidazole derivatives are effective as ulcers)
ES2076517T3 (es)	1995-11-01	Ergolinas disustituidas en posiciones 2,13, su preparacion y utilizacion en medicamentos.
ATE32514T1 (de)	1988-03-15	3-(4'-aminobutylamino)-propylamino-bleomycinderivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.