DK634689A - Anvendelse af castanospermin-estere eller deres salte til fremstilling af laegemidler, der inhiberer tumor-metastaser - Google Patents

Anvendelse af castanospermin-estere eller deres salte til fremstilling af laegemidler, der inhiberer tumor-metastaser Download PDF

Info

Publication number: DK634689A
Authority: DK; Denmark
Prior art keywords: esters; salts; castanospermin; preparation; tumor metastases
Prior art date: 1988-12-15

Application number

DK634689A

Other languages

Danish (da)

English (en)

Other versions

DK634689D0 (da

Inventor

Sai Prasad Sunkara

Paul Saiho Liu

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-15

Filing date

1989-12-14

Publication date

1990-06-16

1989-12-14 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-12-14 Publication of DK634689D0 publication Critical patent/DK634689D0/da

1990-06-16 Publication of DK634689A publication Critical patent/DK634689A/da

Links

206010027476 Metastases Diseases 0.000 title abstract 2
206010028980 Neoplasm Diseases 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical class C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK634689A 1988-12-15 1989-12-14 Anvendelse af castanospermin-estere eller deres salte til fremstilling af laegemidler, der inhiberer tumor-metastaser DK634689A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/284,510 US4952585A (en)	1988-12-15	1988-12-15	Castanospermine esters in the inhibition of tumor metastasis

Publications (2)

Publication Number	Publication Date
DK634689D0 DK634689D0 (da)	1989-12-14
DK634689A true DK634689A (da)	1990-06-16

Family

ID=23090466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK634689A DK634689A (da)	1988-12-15	1989-12-14	Anvendelse af castanospermin-estere eller deres salte til fremstilling af laegemidler, der inhiberer tumor-metastaser

Country Status (12)

Country	Link
US (1)	US4952585A (de)
EP (1)	EP0373663B1 (de)
JP (1)	JP2963476B2 (de)
KR (1)	KR0135278B1 (de)
AT (1)	ATE96320T1 (de)
AU (1)	AU621431B2 (de)
DE (1)	DE68910287T2 (de)
DK (1)	DK634689A (de)
ES (1)	ES2061912T3 (de)
IE (1)	IE62014B1 (de)
PH (1)	PH26024A (de)
ZA (1)	ZA899451B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5004746A (en) *	1987-09-29	1991-04-02	Merrell Dow Pharmaceuticals Inc.	Anti-retroviral castanospermine esters
US4970317A (en) *	1989-08-08	1990-11-13	Merrell Dow Pharmaceuticals Inc.	Process for the preparation of castanospermine esters
CA2287316C (en) *	1997-05-22	2005-02-08	Hoechst Marion Roussel, Inc.	Process for preparing 6-o-monoesters of castanospermine
US5959111A (en) *	1997-05-22	1999-09-28	Hoechst Marion Roussel, Inc.	Process for preparing 6-0-monoesters of castanospermine
US6013459A (en) *	1997-06-12	2000-01-11	Clinical Micro Sensors, Inc.	Detection of analytes using reorganization energy
JP2009545621A (ja) *	2006-08-02	2009-12-24	ユナイテッドセラピューティクスコーポレーション	ウィルス感染症のリポソーム処置
KR20100127842A (ko) *	2008-03-26	2010-12-06	유니버시티 오브 옥스퍼드	소포체 표적화 리포좀
US8226684B2 (en) *	2008-12-22	2012-07-24	Ethicon, Inc.	Surgical sutures having collapsible tissue anchoring protrusions and methods therefor
US8703744B2 (en) *	2009-03-27	2014-04-22	The Chancellor, Masters And Scholars Of The University Of Oxford	Cholesterol level lowering liposomes
WO2017138008A2 (en) *	2016-02-14	2017-08-17	Yeda Research And Development Co. Ltd.	Methods of modulating protein exocytosis and uses of same in therapy
WO2018059214A1 (zh)	2016-09-29	2018-04-05	广州君赫生物科技有限公司	影响saicar合成的化合物及应用
US11684593B2 (en)	2017-04-20	2023-06-27	Geneheal Biotechnology Co., Ltd.	Applications of spermine and its derivative in preparation of antitumor drug
CA3064486C (en)	2017-04-20	2023-08-01	Geneheal Biotechnology Co., Ltd.	Applications of spermidine and its derivatives
US12605349B2 (en)	2024-09-05	2026-04-21	Orbus Therapeutics, Inc.	Methods of treating grade 3 astrocytoma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4792558A (en) *	1987-05-29	1988-12-20	Merrell Dow Pharmaceuticals Inc.	Castanospermine for inhibiting tumor metastasis
CA1315276C (en) *	1987-07-02	1993-03-30	Paul S. Liu	Castanospermine esters and glycosides
US5004746A (en) *	1987-09-29	1991-04-02	Merrell Dow Pharmaceuticals Inc.	Anti-retroviral castanospermine esters
AU618838B2 (en) *	1988-08-10	1992-01-09	Praxis Pharmaceuticals, Inc.	Use of castanospermine as an anti-inflammatory and immunosuppressant agent

1988
- 1988-12-15 US US07/284,510 patent/US4952585A/en not_active Expired - Fee Related
1989
- 1989-12-11 ZA ZA899451A patent/ZA899451B/xx unknown
- 1989-12-13 AU AU46707/89A patent/AU621431B2/en not_active Ceased
- 1989-12-13 KR KR1019890018449A patent/KR0135278B1/ko not_active Expired - Fee Related
- 1989-12-14 AT AT89123189T patent/ATE96320T1/de not_active IP Right Cessation
- 1989-12-14 DK DK634689A patent/DK634689A/da not_active Application Discontinuation
- 1989-12-14 DE DE89123189T patent/DE68910287T2/de not_active Expired - Fee Related
- 1989-12-14 IE IE400989A patent/IE62014B1/en not_active IP Right Cessation
- 1989-12-14 ES ES89123189T patent/ES2061912T3/es not_active Expired - Lifetime
- 1989-12-14 PH PH39704A patent/PH26024A/en unknown
- 1989-12-14 EP EP89123189A patent/EP0373663B1/de not_active Expired - Lifetime
- 1989-12-15 JP JP1324194A patent/JP2963476B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE68910287T2 (de)	1994-03-10
AU621431B2 (en)	1992-03-12
IE894009L (en)	1990-06-15
DK634689D0 (da)	1989-12-14
ES2061912T3 (es)	1994-12-16
EP0373663A2 (de)	1990-06-20
AU4670789A (en)	1990-06-21
EP0373663B1 (de)	1993-10-27
JP2963476B2 (ja)	1999-10-18
EP0373663A3 (en)	1990-09-12
US4952585A (en)	1990-08-28
KR0135278B1 (ko)	1998-04-23
IE62014B1 (en)	1994-12-14
JPH02212427A (ja)	1990-08-23
PH26024A (en)	1992-01-24
KR910011256A (ko)	1991-08-07
ATE96320T1 (de)	1993-11-15
ZA899451B (en)	1990-09-26
DE68910287D1 (de)	1993-12-02

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Legal Events

Date	Code	Title	Description
2004-08-09	AHB	Application shelved due to non-payment