DK653088D0 - Anti-inflammatoriske derivater af di-tert-butylphenolforbindelser og farmaceutisk middel omfattende samme - Google Patents

Anti-inflammatoriske derivater af di-tert-butylphenolforbindelser og farmaceutisk middel omfattende samme

Info

Publication number: DK653088D0
Authority: DK; Denmark
Prior art keywords: compounds; butylphenolic; tert; pharmaceutical composition; inflammatory derivatives
Prior art date: 1987-11-23

Application number

DK653088A

Other languages

English (en)

Other versions

DK653088A (da

DK173367B1 (da

Inventor

Roy Lee Martin Dobson

Maurice Edward Loomans

Randall Stryker Matthews

Joseph Arthur Miller

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-23

Filing date

1988-11-23

Publication date

1988-11-23

1988-11-23 Application filed by Procter & Gamble filed Critical Procter & Gamble

1988-11-23 Publication of DK653088D0 publication Critical patent/DK653088D0/da

1989-05-24 Publication of DK653088A publication Critical patent/DK653088A/da

2000-08-21 Application granted granted Critical

2000-08-21 Publication of DK173367B1 publication Critical patent/DK173367B1/da

Links

150000001875 compounds Chemical class 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
230000003110 anti-inflammatory effect Effects 0.000 title 1
206010061218 Inflammation Diseases 0.000 abstract 1
125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)

DK198806530A 1987-11-23 1988-11-23 Anti-inflammatoriske derivater af di-tert-butylphenol, farmaceutisk præparat omfattende samme samt anvendelse af et sådant DK173367B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12375687		1987-11-23
US07/123,756 US4849428A (en)	1987-11-23	1987-11-23	Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use

Publications (3)

Publication Number	Publication Date
DK653088D0 true DK653088D0 (da)	1988-11-23
DK653088A DK653088A (da)	1989-05-24
DK173367B1 DK173367B1 (da)	2000-08-21

Family

ID=22410695

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198806530A DK173367B1 (da)	1987-11-23	1988-11-23	Anti-inflammatoriske derivater af di-tert-butylphenol, farmaceutisk præparat omfattende samme samt anvendelse af et sådant

Country Status (14)

Country	Link
US (1)	US4849428A (da)
EP (1)	EP0322004B1 (da)
JP (1)	JP2602931B2 (da)
KR (1)	KR970011460B1 (da)
AT (1)	ATE71623T1 (da)
AU (1)	AU621571B2 (da)
CA (1)	CA1308110C (da)
DE (1)	DE3867827D1 (da)
DK (1)	DK173367B1 (da)
IE (1)	IE61197B1 (da)
IL (1)	IL88365A (da)
NZ (1)	NZ227039A (da)
PH (1)	PH25855A (da)
ZA (1)	ZA888727B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4982006A (en) *	1987-12-18	1991-01-01	Norwich Eaton Pharmaceuticals, Inc.	Process for the preparation of certain substituted aromatic compounds
GB8827850D0 (en) *	1988-11-29	1988-12-29	Shell Int Research	Biocidal compounds
US5189066A (en) *	1989-11-22	1993-02-23	The Procter & Gamble Company	Pharmaceutical compositions of tebufelone
US5126487A (en) *	1991-03-26	1992-06-30	The Procter & Gamble Company	Process for the preparation of 2-alkyl-4-acyl-6-tert-butylphenol compounds
US5281420A (en) *	1992-05-19	1994-01-25	The Procter & Gamble Company	Solid dispersion compositions of tebufelone
JPH10506615A (ja) *	1994-07-27	1998-06-30	ザ、プロクター、エンド、ギャンブル、カンパニー	抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物
US5674891A (en) *	1994-07-27	1997-10-07	The Procter & Gamble Company	Dihydrobenzothiophene compounds useful as anti-inflammatory agents
US5684002A (en) *	1994-09-07	1997-11-04	The Procter & Gamble Company	Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5618835A (en) *	1996-02-01	1997-04-08	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5821250A (en) *	1996-02-01	1998-10-13	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) *	1996-02-01	1997-09-30	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5686471A (en) *	1996-02-01	1997-11-11	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) *	1996-02-01	1997-11-04	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684041A (en) *	1996-02-01	1997-11-04	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5750543A (en) *	1996-02-01	1998-05-12	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
FR2744452B1 (fr) *	1996-02-06	1998-03-06	Cird Galderma	Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
US7479507B2 (en) *	2003-01-14	2009-01-20	Adam Heller	Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1922815A1 (de) *	1969-05-05	1970-11-12	Merck Anlagen Gmbh	Phenolaether und Phenolester als Stabilisatoren
US3829446A (en) *	1970-10-15	1974-08-13	Pfizer	Oxobenzofuran intermediates
US3862133A (en) *	1973-04-30	1975-01-21	Goodrich Co B F	Gamma-lactones of o-hydroxyphenylacetic acids
US4013690A (en) *	1974-02-05	1977-03-22	Sandoz Ltd.	Organic compounds
DE2608697A1 (de) *	1975-03-12	1976-09-23	Sandoz Ag	Neue organische verbindungen, ihre herstellung und verwendung
US4130666A (en) *	1977-05-16	1978-12-19	Riker Laboratories, Inc.	Anti-inflammatory method
DE2803544A1 (de) *	1978-01-27	1979-08-02	Sandoz Ag	Neue benzofuran- und benzoxepinderivate
GB2042562B (en) *	1979-02-05	1983-05-11	Sandoz Ltd	Stabilising polymers
DE2931672A1 (de) *	1979-08-04	1981-02-26	Basf Ag	Substituierte 2,3-dihydrobenzofurylmethylester, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
US4440784A (en) *	1981-02-05	1984-04-03	Kanegafuchi Chemical Industry Company, Ltd.	Anti-inflammatory, analgesic, and antipyretic pharmaceutical composition
US4431656A (en) *	1981-02-05	1984-02-14	Kanegafuchi Chemical Industry Company Limited	3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient
US4514415A (en) *	1981-10-28	1985-04-30	Ciba Geigy Corporation	Benzofuran-2(3H)-ones used as anti-inflammatory agents
JPH0623194B2 (ja) *	1985-03-23	1994-03-30	鐘淵化学工業株式会社	新規ラクタム誘導体及び抗炎症剤
US4711903A (en) *	1986-01-31	1987-12-08	G. D. Searle & Co.	Phenolic thioethers as inhibitors of 5-lipoxygenase
US4708966A (en) *	1986-06-27	1987-11-24	The Procter & Gamble Company	Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation
US4911754A (en) *	1987-07-16	1990-03-27	American Cyanamid Company	Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds
JPH0654315A (ja) *	1992-07-31	1994-02-25	Canon Inc	動画像符号化方法及び装置

1987
- 1987-11-23 US US07/123,756 patent/US4849428A/en not_active Expired - Lifetime
1988
- 1988-11-11 IL IL8836588A patent/IL88365A/en not_active IP Right Cessation
- 1988-11-17 PH PH37827A patent/PH25855A/en unknown
- 1988-11-18 EP EP88202593A patent/EP0322004B1/en not_active Expired - Lifetime
- 1988-11-18 AT AT88202593T patent/ATE71623T1/de not_active IP Right Cessation
- 1988-11-18 DE DE8888202593T patent/DE3867827D1/de not_active Expired - Lifetime
- 1988-11-22 IE IE349188A patent/IE61197B1/en not_active IP Right Cessation
- 1988-11-22 NZ NZ227039A patent/NZ227039A/xx unknown
- 1988-11-22 AU AU25771/88A patent/AU621571B2/en not_active Ceased
- 1988-11-22 CA CA000583746A patent/CA1308110C/en not_active Expired - Lifetime
- 1988-11-22 ZA ZA888727A patent/ZA888727B/xx unknown
- 1988-11-23 KR KR1019880015404A patent/KR970011460B1/ko not_active Expired - Fee Related
- 1988-11-23 DK DK198806530A patent/DK173367B1/da not_active IP Right Cessation
- 1988-11-24 JP JP63297155A patent/JP2602931B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA888727B (en)	1989-08-30
NZ227039A (en)	1990-10-26
JPH01250372A (ja)	1989-10-05
JP2602931B2 (ja)	1997-04-23
IL88365A0 (en)	1989-06-30
IL88365A (en)	1994-02-27
AU2577188A (en)	1989-05-25
KR890008123A (ko)	1989-07-08
ATE71623T1 (de)	1992-02-15
IE883491L (en)	1989-05-23
DE3867827D1 (de)	1992-02-27
EP0322004B1 (en)	1992-01-15
DK653088A (da)	1989-05-24
KR970011460B1 (ko)	1997-07-11
IE61197B1 (en)	1994-10-19
DK173367B1 (da)	2000-08-21
AU621571B2 (en)	1992-03-19
PH25855A (en)	1991-12-02
US4849428A (en)	1989-07-18
CA1308110C (en)	1992-09-29
EP0322004A1 (en)	1989-06-28

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Legal Events

Date	Code	Title	Description
2000-08-21	B1	Patent granted (law 1993)
2006-07-10	PBP	Patent lapsed	Country of ref document: DK