DK654589A - Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne - Google Patents

Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne Download PDF

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Publication number
DK654589A
DK654589A DK654589A DK654589A DK654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A
Authority
DK
Denmark
Prior art keywords
derivatives
procedures
preparing
pharmaceutical agents
agents containing
Prior art date
Application number
DK654589A
Other languages
Danish (da)
English (en)
Other versions
DK654589D0 (da
Inventor
Philip Neil Edwards
Jean-Marc Marie Mauri Girodeau
Original Assignee
Ici Pharma
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma, Ici Plc filed Critical Ici Pharma
Publication of DK654589D0 publication Critical patent/DK654589D0/da
Publication of DK654589A publication Critical patent/DK654589A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK654589A 1988-12-23 1989-12-21 Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne DK654589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88403313 1988-12-23
EP89401491 1989-05-31

Publications (2)

Publication Number Publication Date
DK654589D0 DK654589D0 (da) 1989-12-21
DK654589A true DK654589A (da) 1990-06-24

Family

ID=26118235

Family Applications (1)

Application Number Title Priority Date Filing Date
DK654589A DK654589A (da) 1988-12-23 1989-12-21 Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne

Country Status (16)

Country Link
US (1) US5098930A (fr)
EP (1) EP0375404B1 (fr)
JP (1) JPH03135975A (fr)
AU (1) AU624663B2 (fr)
CA (1) CA2006377A1 (fr)
DE (1) DE68913022T2 (fr)
DK (1) DK654589A (fr)
ES (1) ES2062051T3 (fr)
FI (1) FI896014A7 (fr)
GB (1) GB8926981D0 (fr)
HU (1) HUT52767A (fr)
IE (1) IE63047B1 (fr)
IL (1) IL92556A (fr)
NO (1) NO895086L (fr)
NZ (1) NZ231665A (fr)
PT (1) PT92699B (fr)

Families Citing this family (60)

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IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
EP0462830B1 (fr) * 1990-06-21 1995-10-18 Zeneca Limited Dérivés cycliques d'éther
IE911853A1 (en) * 1990-06-21 1992-01-01 Ici Plc Heterocyclene derivatives
AU637500B2 (en) * 1990-06-21 1993-05-27 Zeneca Limited Bicyclic heterocyclic compounds
GB9113137D0 (en) * 1990-07-13 1991-08-07 Ici Plc Thioxo heterocycles
US5272173A (en) * 1990-11-28 1993-12-21 Imperial Chemical Industries Plc 5-lipoxygenase inhibitors
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
CA2058254A1 (fr) * 1991-01-15 1992-07-16 John Francis Kingston Derives de benzodioxole
AU645159B2 (en) * 1991-01-17 1994-01-06 Ici Pharma Sulphonamide derivatives
US5258399A (en) * 1991-01-17 1993-11-02 Imperial Chemical Industries Plc Sulphonamide derivatives
EP0501579A1 (fr) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Lactones naphthalèniques comme inhibiteurs de la biosynthèse de leukotriène
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
EP0501578A1 (fr) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Acides pyranylphényle hydroxyalkylenaphthaléniques et leur utilisation comme inhibiteurs de la biosynthèse de leukotriène
US5227399A (en) * 1991-02-28 1993-07-13 Merck Frosst Canada, Inc. Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
EP0505122A1 (fr) * 1991-03-21 1992-09-23 Zeneca Limited Dérivés alpha, alpha-dialkylbenzyle
EP0532239B1 (fr) * 1991-09-10 1995-12-13 Zeneca Limited Dérivés de benzenesulfonamide comme inhibiteurs de 5-lipoxygenase
EP0540165A1 (fr) * 1991-10-03 1993-05-05 Zeneca Limited Dérivés d'acide alcanoique
GB9300894D0 (en) * 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
EP0555067A1 (fr) * 1992-02-07 1993-08-11 Zeneca Limited Dérivés d'hydroxylamine comme inhibiteurs de 5-lipoxygénase
CA2094465A1 (fr) * 1992-04-23 1993-10-24 Pierre Andre Raymond Bruneau Derives de cycloalcane
CA2095006A1 (fr) * 1992-05-12 1993-11-13 Philip Neil Edwards Derives oxime
CA2095005A1 (fr) * 1992-05-12 1993-11-13 Philip Neil Edwards Derives hydroxylamine
EP0570196B1 (fr) * 1992-05-12 1996-03-06 Zeneca Limited Dérivés d'oximes
EP0570197B1 (fr) * 1992-05-12 1995-12-13 Zeneca Limited Dérivés d'hydroxylamine
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
AU4444393A (en) * 1992-09-01 1994-03-10 Zeneca Limited Pyrrolidine derivatives
EP0586229A1 (fr) * 1992-09-01 1994-03-09 Zeneca Limited 3-Hydroxy-3-(akyl-subst.)-pyrrolidines comme inhibiteur de la 5-lipoxygénase
US5354865A (en) * 1992-09-10 1994-10-11 Abbott Laboratories Phenylmethyl derivatives having lipoxygenase inhibitory activity
GR920100426A (el) * 1992-10-08 1994-06-30 Ici Pharma Παράγωγα βενζολοσουλφοναμιδίου.
IL109254A (en) * 1993-04-29 1999-03-12 Zeneca Ltd Tetrahydropyran and tetrahydrofuran ether derivatives their preparation and pharmaceutical compositions comprising them
ES2103130T3 (es) * 1993-06-14 1997-08-16 Pfizer Inhibidores imidazoles como la lipoxigenasa.
EP0636624A1 (fr) * 1993-07-27 1995-02-01 Zeneca Limited Dérivés de thiazole comme inhibiteurs de lipoxygénase
ZA945250B (en) * 1993-07-27 1995-01-27 Zeneca Ltd Thiazole derivatives
IL110280A0 (en) * 1993-07-27 1994-10-21 Zeneca Ltd Thiazole derivatives
US5407959A (en) * 1993-11-12 1995-04-18 Abbott Laboratories (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
US5446062A (en) * 1993-11-12 1995-08-29 Abbott Laboratories ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase
FI963882A7 (fi) * 1994-03-28 1996-09-27 Pfizer Bentsotiatsolijohdannaiset 5-lipoksigenaasibiosynteesin estoaineina
WO1995030669A1 (fr) * 1994-05-06 1995-11-16 Zeneca Limited Derives ether et compositions pharmaceutiques les contenant
WO1999023074A1 (fr) * 1997-11-03 1999-05-14 Aventis Research & Technologies Gmbh & Co. Kg Derives de naphtalene fluores et leur utilisation dans des melanges a cristaux liquides
CA2269561C (fr) * 1998-04-22 2007-06-05 Dainippon Ink And Chemicals, Inc. Derive de naphtalene et composition a cristaux liquides comprenant celui-ci
CN1468055A (zh) * 2000-10-03 2004-01-14 �����ɷ� 苯基丙炔基羟吡啶除草剂
US6825221B2 (en) 2001-10-18 2004-11-30 Allergan, Inc. Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain
WO2006045010A2 (fr) 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes et chalcones utilises pour la prevention et le traitement de maladies cardio-vasculaires
US8410109B2 (en) 2005-07-29 2013-04-02 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
PT2118074E (pt) 2007-02-01 2014-03-20 Resverlogix Corp Compostos para a prevenção e tratamento de doenças cardiovasculares
SI2346837T1 (sl) 2008-06-26 2015-05-29 Resverlogix Corporation Postopki pripravljanja kinazolinonskih derivatov
US8952021B2 (en) 2009-01-08 2015-02-10 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
KR101913109B1 (ko) 2009-03-18 2018-10-31 리스버로직스 코퍼레이션 신규한 소염제
US9757368B2 (en) 2009-04-22 2017-09-12 Resverlogix Corp. Anti-inflammatory agents
CA2851996C (fr) 2011-11-01 2020-01-07 Resverlogix Corp. Compositions pharmaceutiques pour des quinazolinones substituees
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases

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US3661917A (en) * 1970-05-21 1972-05-09 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols
US3743737A (en) * 1970-05-21 1973-07-03 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions
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IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
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NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
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FR2611714A2 (fr) * 1986-04-23 1988-09-09 Rhone Poulenc Agrochimie Composes a groupements triazole ou imidazole et tetrahydrofuran, utilisation de ceux-ci a titre de fongicides et procedes de preparation
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IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles

Also Published As

Publication number Publication date
DE68913022D1 (de) 1994-03-24
AU624663B2 (en) 1992-06-18
EP0375404B1 (fr) 1994-02-09
NO895086D0 (no) 1989-12-18
FI896014A7 (fi) 1990-06-24
US5098930A (en) 1992-03-24
FI896014A0 (fi) 1989-12-15
DK654589D0 (da) 1989-12-21
IE63047B1 (en) 1995-03-22
IL92556A (en) 1994-04-12
AU4619889A (en) 1990-06-28
IL92556A0 (en) 1990-08-31
DE68913022T2 (de) 1994-05-11
NO895086L (no) 1990-06-25
NZ231665A (en) 1992-02-25
EP0375404A3 (fr) 1991-01-16
EP0375404A2 (fr) 1990-06-27
IE893880L (en) 1990-06-23
CA2006377A1 (fr) 1990-06-23
PT92699B (pt) 1995-09-12
GB8926981D0 (en) 1990-01-17
JPH03135975A (ja) 1991-06-10
PT92699A (pt) 1990-06-29
HU896626D0 (en) 1990-02-28
HUT52767A (en) 1990-08-28
ES2062051T3 (es) 1994-12-16

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