DK658888A - Diltiazem-praeparat med langsom afgivelse - Google Patents

Diltiazem-praeparat med langsom afgivelse

Info

Publication number
DK658888A
DK658888A DK658888A DK658888A DK658888A DK 658888 A DK658888 A DK 658888A DK 658888 A DK658888 A DK 658888A DK 658888 A DK658888 A DK 658888A DK 658888 A DK658888 A DK 658888A
Authority
DK
Denmark
Prior art keywords
diltiazem
delivery preparation
slow delivery
slow
preparation
Prior art date
Application number
DK658888A
Other languages
English (en)
Other versions
DK171155B1 (da
DK658888D0 (da
Inventor
Jean-Francois Boyer
Patrice Debregeas
Gerard Leduc
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of DK658888D0 publication Critical patent/DK658888D0/da
Publication of DK658888A publication Critical patent/DK658888A/da
Application granted granted Critical
Publication of DK171155B1 publication Critical patent/DK171155B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK658888A 1987-11-26 1988-11-25 Diltiazem-præparat med langsom afgivelse DK171155B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8716425A FR2623714B1 (fr) 1987-11-26 1987-11-26 Forme a liberation prolongee du diltiazem, et son medicament ainsi obtenu
FR8716425 1987-11-26

Publications (3)

Publication Number Publication Date
DK658888D0 DK658888D0 (da) 1988-11-25
DK658888A true DK658888A (da) 1989-05-27
DK171155B1 DK171155B1 (da) 1996-07-08

Family

ID=9357210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK658888A DK171155B1 (da) 1987-11-26 1988-11-25 Diltiazem-præparat med langsom afgivelse

Country Status (13)

Country Link
US (2) US4960596A (da)
EP (1) EP0318398B1 (da)
JP (1) JP2881442B2 (da)
KR (1) KR890007743A (da)
AU (1) AU610951B2 (da)
CA (1) CA1331740C (da)
DE (1) DE3853341T2 (da)
DK (1) DK171155B1 (da)
ES (1) ES2072267T3 (da)
FR (1) FR2623714B1 (da)
IL (1) IL88426A (da)
NZ (1) NZ227072A (da)
ZA (1) ZA888757B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA899071B (en) * 1988-11-30 1990-08-29 Schering Corp Sustained release diltiazem formulation
SE8902699D0 (sv) * 1989-08-09 1989-08-09 Lejus Medical Ab Diltiazem containing pharmaceutical compositios
FR2677886B1 (fr) * 1991-06-18 1995-03-31 Adir Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale.
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
US5229135A (en) * 1991-11-22 1993-07-20 Prographarm Laboratories Sustained release diltiazem formulation
US5637582A (en) * 1992-10-23 1997-06-10 Tanabe Seiyaku Co., Ltd. Peripheral circulation improving agent
DE69313775T2 (de) * 1992-10-23 1998-01-22 Tanabe Seiyaku Co Mittel zur Verbesserung der peripheren Durchblutung
US5834024A (en) * 1995-01-05 1998-11-10 Fh Faulding & Co. Limited Controlled absorption diltiazem pharmaceutical formulation
FR2742660B1 (fr) * 1995-12-22 1998-04-03 Ethypharm Lab Prod Ethiques Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif
FR2754710B1 (fr) * 1996-10-22 1998-12-31 Prographarm Lab Procede de preparation d'une forme pharmaceutique multiparticulaire a liberation controlee plurisequentielle
US5914134A (en) * 1997-01-27 1999-06-22 Wockhardt Europe Limited Process for the pulsatile delivery of diltiazem HCL and product produced thereby
US6524620B2 (en) * 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
JP2006501261A (ja) * 2002-09-09 2006-01-12 バイオヴェイル ラボラトリーズ インコーポレイテッド 時間治療用ジルチアゼム製剤およびその投与
JP5171038B2 (ja) * 2003-10-10 2013-03-27 エティファルム イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
IT1175814B (it) * 1984-03-09 1987-07-15 Luso Farmaco Inst Resine solfoniche ad attivita' terapeutica,loro preparazione e composizioni farmaceutiche che le contengono
CA1268710A (en) * 1984-11-06 1990-05-08 Nagin K. Patel Drug in bead form and process for preparing same

Also Published As

Publication number Publication date
NZ227072A (en) 1990-07-26
DK171155B1 (da) 1996-07-08
DK658888D0 (da) 1988-11-25
FR2623714A1 (fr) 1989-06-02
ES2072267T3 (es) 1995-07-16
USRE35903E (en) 1998-09-22
US4960596A (en) 1990-10-02
IL88426A0 (en) 1989-06-30
ZA888757B (en) 1989-08-30
JP2881442B2 (ja) 1999-04-12
DE3853341T2 (de) 1995-11-09
AU2590988A (en) 1989-06-01
JPH01168617A (ja) 1989-07-04
AU610951B2 (en) 1991-05-30
CA1331740C (en) 1994-08-30
IL88426A (en) 1993-06-10
FR2623714B1 (fr) 1990-04-20
DE3853341D1 (de) 1995-04-20
EP0318398A1 (fr) 1989-05-31
EP0318398B1 (fr) 1995-03-15
KR890007743A (ko) 1989-07-05

Similar Documents

Publication Publication Date Title
DK686187D0 (da) Veterinaert praeparat
FR2605214B1 (fr) Prothese perihepatique
DK184788A (da) Cytotoxisk praeparat
DK130287D0 (da) Oralt praeparat
FI882625L (fi) Fermentointiin liittyviä parannuksia
DK658888A (da) Diltiazem-praeparat med langsom afgivelse
NO172325C (no) Munnpreparat
FI88164C (fi) Metalljonskelat med en kelaterande dipyridoxalfosfatfoerening
DE3856139D1 (de) Mikroprozessor
FR2617040B1 (fr) Prothese cotyloidienne
DK10087D0 (da) Praeparat
FI903296A7 (fi) VIP-analogit II
KR890700356A (ko) 신규의 백신
FR2611486B1 (fr) Prothese uretrale
DK244488A (da) Efterskummende praeparat
DK255787D0 (da) Praeparat
FI941887A0 (fi) Suoraviivainen syöttökone
FI882238L (fi) Foerbaettringar i samband med organiska foereningar
FR2624353B1 (fr) Couche-culotte
DK8188A (da) Veterinaert praeparat
DK30788A (da) Co-vaccinationspraeparat
AT386333B (de) Artikulator
DK662587D0 (da) Herbicidt praeparat
ATA171086A (de) Implantat
DK504688D0 (da) Appetitundertrykkende tandplejemiddel

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired