DK659287A - Ekspression af det klonede lysostaphin-gen - Google Patents

Ekspression af det klonede lysostaphin-gen

Info

Publication number
DK659287A
DK659287A DK659287A DK659287A DK659287A DK 659287 A DK659287 A DK 659287A DK 659287 A DK659287 A DK 659287A DK 659287 A DK659287 A DK 659287A DK 659287 A DK659287 A DK 659287A
Authority
DK
Denmark
Prior art keywords
lysostaphin
pjp1
provides
pdf8
prg5
Prior art date
Application number
DK659287A
Other languages
English (en)
Other versions
DK659287D0 (da
DK174941B1 (da
Inventor
Paul A Recsei
Original Assignee
New York Health Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Health Res Inst filed Critical New York Health Res Inst
Publication of DK659287D0 publication Critical patent/DK659287D0/da
Publication of DK659287A publication Critical patent/DK659287A/da
Application granted granted Critical
Publication of DK174941B1 publication Critical patent/DK174941B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DK198706592A 1986-04-16 1987-12-15 DNA-fragment kodende for lysostaphin, rekombinante plasmider indeholdende dette, tranformerede mikroorganismer samt ekspession af det klonede lysostaphin DK174941B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US85240786A 1986-04-16 1986-04-16
US85240786 1986-04-16
US07/034,464 US4931390A (en) 1986-04-16 1987-04-10 Expression of the cloned lysostaphin gene
US3446487 1987-04-10
PCT/US1987/000873 WO1987006264A1 (en) 1986-04-16 1987-04-15 Expression of the cloned lysostaphin gene
US8700873 1987-04-15

Publications (3)

Publication Number Publication Date
DK659287D0 DK659287D0 (da) 1987-12-15
DK659287A true DK659287A (da) 1987-12-15
DK174941B1 DK174941B1 (da) 2004-03-08

Family

ID=26710985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198706592A DK174941B1 (da) 1986-04-16 1987-12-15 DNA-fragment kodende for lysostaphin, rekombinante plasmider indeholdende dette, tranformerede mikroorganismer samt ekspession af det klonede lysostaphin

Country Status (15)

Country Link
US (1) US4931390A (da)
EP (1) EP0299978B1 (da)
JP (1) JP2963695B2 (da)
AT (1) ATE92524T1 (da)
AU (1) AU616379B2 (da)
CA (1) CA1297051C (da)
DE (1) DE3786918T2 (da)
DK (1) DK174941B1 (da)
FI (1) FI96322C (da)
HU (1) HU205386B (da)
IE (1) IE60769B1 (da)
IL (1) IL82260A (da)
NZ (1) NZ219998A (da)
PT (1) PT84705B (da)
WO (1) WO1987006264A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260212A (en) * 1987-02-09 1993-11-09 Quest International Flavors & Food Ingredients Co., Division Of Indopco Cloned gene encoding for bacteriocin from Pediococcus acidilactici
US5858962A (en) * 1987-05-11 1999-01-12 Ambi Inc. Composition for treating mastitis and other staphylococcal infections
US5011772A (en) * 1988-02-05 1991-04-30 Public Health Research Institute Of The City Of N.Y. High yield protein production system
WO1989010976A1 (en) * 1988-05-05 1989-11-16 The Public Health Research Institute Of The City O Protease-deficient gram-positive bacteria and their use as host organisms for the production of recombinant products
CA2009336A1 (en) * 1989-07-03 1991-01-03 Peter A. Vandenbergh Cloned gene encoding for bacteriocin from pediococcus acidilactici
DE4425645A1 (de) * 1994-07-20 1996-02-22 Mueller Karl & Co Kg Deletiertes Lysostaphingen von Staphylococcus simulans
NZ311535A (en) * 1995-06-23 2001-05-25 Ambi Inc A method for the control of antibiotic-resistant gram positive bacteria and treatment of infection
WO1997008553A1 (en) * 1995-08-22 1997-03-06 The Regents Of The University Of California Targeting of proteins to the cell wall of gram-positive bacteria
US5910479A (en) * 1996-10-18 1999-06-08 Ambi Inc. Method for the treatment of Streptococcus pneumoniae infection
HUP0002662A3 (en) * 1997-07-23 2003-08-28 Ambi Inc Pharmaceutical compositions containing lysostaphin alone or in combination with an antibiotic for the treatment of staphylococcal infections
US6028051A (en) * 1997-07-23 2000-02-22 Ambi Inc. Method for the treatment of staphylococcal disease
US6875903B2 (en) * 1998-06-22 2005-04-05 University Of Vermont Treatment of Staphylococcus infections
US7091332B1 (en) 1998-06-22 2006-08-15 University Of Vermont Treatment of staphylococcus infections
AU4706799A (en) * 1998-06-22 2000-01-10 University Of Vermont And State Agricultural College, The Treatment of (staphylococcus) infections
JP4416866B2 (ja) * 1998-07-30 2010-02-17 オリエンタル酵母工業株式会社 カルシウム測定用液状試薬
US6569830B1 (en) * 1999-03-05 2003-05-27 Ambi, Inc. Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains
ATE430799T1 (de) * 1999-10-19 2009-05-15 Bharat Biotech International L Expression von rekombinantem, reifem lysostaphin
AU2002367820B2 (en) * 2001-12-21 2007-11-01 Biosynexus Incorporated Truncated lysostaphin molecule with enhanced staphylolytic activity
US7452533B2 (en) * 2002-03-26 2008-11-18 Biosynexus Incorporated Antimicrobial polymer conjugate containing lysostaphin and polyethylene glycol
CN1642496A (zh) * 2002-03-26 2005-07-20 拜奥辛尼克休斯公司 细菌生物薄膜的酶破坏
US20100221237A1 (en) * 2003-03-26 2010-09-02 Biosynexus Incorporated Enzyme disruption of bacterial biofilms
AU2003292690B2 (en) 2003-03-28 2008-11-20 Mitsui Chemicals, Inc. Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization
CN100485031C (zh) * 2004-09-02 2009-05-06 上海高科联合生物技术研发有限公司 一种溶葡萄球菌酶工业化纯化工艺
WO2006110776A2 (en) 2005-04-12 2006-10-19 Nektar Therapeutics Al, Corporation Polyethylene glycol cojugates of antimicrobial agents
CN100475965C (zh) * 2005-07-22 2009-04-08 上海高科联合生物技术研发有限公司 一种大肠杆菌高效外分泌表达溶葡萄球菌酶的方法
US20080095756A1 (en) * 2006-09-05 2008-04-24 Biosynexus Incorporated Compositions Comprising Lysostaphin Variants And Methods Of Using The Same
EP2179052B1 (en) * 2007-07-09 2012-11-14 Microsens Medtech Ltd Detection of micro-organisms based on their nad-dependent dna ligase activity
WO2009114520A2 (en) * 2008-03-10 2009-09-17 Pharmain Corporation Compositions for treatment with metallopeptidases, methods of making and using the same
WO2012050787A1 (en) 2010-09-29 2012-04-19 Ibis Biosciences, Inc. Fungal nucleic acid extraction
WO2015020765A2 (en) 2013-08-06 2015-02-12 Trustees Of Dartmouth College Unglycosylated lysostaphin variant protein
EP3086805B1 (en) 2013-12-28 2018-10-03 Longhorn Vaccines and Diagnostics, LLC Use of glycyl-glycine endopeptidase for treating mycobacteria infections
WO2015175774A1 (en) 2014-05-14 2015-11-19 Trustees Of Dartmouth College Deimmunized lysostaphin and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278378A (en) * 1962-04-19 1966-10-11 Schindler Charles Alvin Staphylococcus-derived antibiotic
US4467036A (en) * 1981-11-12 1984-08-21 The Board Of Regents Of The University Of Washington Bacillus thuringiensis crystal protein in Escherichia coli
US4617266A (en) * 1983-04-28 1986-10-14 Genex Corporation Production of Protein A

Also Published As

Publication number Publication date
DE3786918D1 (de) 1993-09-09
CA1297051C (en) 1992-03-10
AU616379B2 (en) 1991-10-31
IE870980L (en) 1987-10-16
DE3786918T2 (de) 1993-11-11
ATE92524T1 (de) 1993-08-15
JP2963695B2 (ja) 1999-10-18
IL82260A0 (en) 1987-10-30
HU205386B (en) 1992-04-28
NZ219998A (en) 1991-05-28
JPH01503036A (ja) 1989-10-19
FI96322B (fi) 1996-02-29
WO1987006264A1 (en) 1987-10-22
DK659287D0 (da) 1987-12-15
IE60769B1 (en) 1994-08-10
FI96322C (fi) 1996-06-10
FI884691L (fi) 1988-10-12
DK174941B1 (da) 2004-03-08
PT84705B (pt) 1989-11-30
FI884691A0 (fi) 1988-10-12
PT84705A (en) 1987-05-01
HUT50874A (en) 1990-03-28
EP0299978A1 (en) 1989-01-25
US4931390A (en) 1990-06-05
AU7302187A (en) 1987-11-09
IL82260A (en) 1992-08-18
EP0299978B1 (en) 1993-08-04

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