DK67683A - Fremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thio-phener - Google Patents

Fremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thio-phener Download PDF

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Publication number
DK67683A
DK67683A DK67683A DK67683A DK67683A DK 67683 A DK67683 A DK 67683A DK 67683 A DK67683 A DK 67683A DK 67683 A DK67683 A DK 67683A DK 67683 A DK67683 A DK 67683A
Authority
DK
Denmark
Prior art keywords
diaryl
phenes
thio
halogen
preparing
Prior art date
Application number
DK67683A
Other languages
English (en)
Other versions
DK161320B (da
DK67683D0 (da
DK161320C (da
Inventor
Stephen Barry Haber
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK67683D0 publication Critical patent/DK67683D0/da
Publication of DK67683A publication Critical patent/DK67683A/da
Publication of DK161320B publication Critical patent/DK161320B/da
Application granted granted Critical
Publication of DK161320C publication Critical patent/DK161320C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Measuring Volume Flow (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DK067683A 1982-03-03 1983-02-16 Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophener DK161320C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35430082A 1982-03-03 1982-03-03
US35430082 1982-03-03

Publications (4)

Publication Number Publication Date
DK67683D0 DK67683D0 (da) 1983-02-16
DK67683A true DK67683A (da) 1983-09-04
DK161320B DK161320B (da) 1991-06-24
DK161320C DK161320C (da) 1991-12-09

Family

ID=23392697

Family Applications (1)

Application Number Title Priority Date Filing Date
DK067683A DK161320C (da) 1982-03-03 1983-02-16 Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophener

Country Status (18)

Country Link
EP (1) EP0087629B1 (da)
JP (1) JPS58159489A (da)
AT (1) ATE17480T1 (da)
AU (1) AU553269B2 (da)
CA (1) CA1242725A (da)
DE (1) DE3361812D1 (da)
DK (1) DK161320C (da)
ES (1) ES520218A0 (da)
FI (1) FI79308C (da)
GR (1) GR78135B (da)
IE (1) IE54816B1 (da)
IL (1) IL67940A (da)
NO (1) NO155198B (da)
NZ (1) NZ203317A (da)
PH (1) PH18061A (da)
PT (1) PT76247B (da)
SU (1) SU1250172A3 (da)
ZA (1) ZA831046B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346175A1 (de) * 1983-12-21 1985-07-11 Merck Patent Gmbh, 6100 Darmstadt Pyridylthiophene
NZ211146A (en) * 1984-02-29 1987-10-30 Merck & Co Inc 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions
GB9012936D0 (en) * 1990-06-11 1990-08-01 Fujisawa Pharmaceutical Co Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
US5571810A (en) * 1990-06-11 1996-11-05 Fujisawa Pharmaceutical Co., Ltd. Thiophene derivatives
ATE160345T1 (de) * 1993-01-15 1997-12-15 Searle & Co 3,4-diarylthiophene und analoga davon, sowie deren verwendung als entzündungshemmende mittel
US6492413B2 (en) 1993-01-15 2002-12-10 G.D. Searle & Co. 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
GB9420616D0 (en) * 1994-10-12 1994-11-30 Merck Sharp & Dohme Method, compositions and use
CA2161789A1 (en) * 1993-05-13 1994-11-24 Jacques Yves Gauthier 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5840746A (en) * 1993-06-24 1998-11-24 Merck Frosst Canada, Inc. Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
DE10001166A1 (de) 2000-01-13 2001-07-19 Merckle Gmbh Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung
AUPR283801A0 (en) * 2001-02-01 2001-03-01 Australian National University, The Chemical compounds and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302461A (en) * 1979-08-09 1981-11-24 E. I. Du Pont De Nemours And Company Antiinflammatory 5-substituted-2,3-diarylthiophenes
JPS6028837B2 (ja) * 1979-08-09 1985-07-06 イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤
US4381311A (en) * 1980-12-29 1983-04-26 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols

Also Published As

Publication number Publication date
IE54816B1 (en) 1990-02-14
AU1146083A (en) 1983-09-08
NO155198B (no) 1986-11-17
EP0087629A2 (en) 1983-09-07
DK161320B (da) 1991-06-24
DK67683D0 (da) 1983-02-16
CA1242725A (en) 1988-10-04
PT76247A (en) 1983-03-01
NZ203317A (en) 1985-07-12
GR78135B (da) 1984-09-26
SU1250172A3 (ru) 1986-08-07
EP0087629A3 (en) 1983-10-19
PH18061A (en) 1985-03-18
ES8403884A1 (es) 1984-04-01
PT76247B (en) 1986-02-04
FI79308B (fi) 1989-08-31
JPS58159489A (ja) 1983-09-21
ATE17480T1 (de) 1986-02-15
AU553269B2 (en) 1986-07-10
ZA831046B (en) 1984-09-26
FI830523A0 (fi) 1983-02-16
DK161320C (da) 1991-12-09
ES520218A0 (es) 1984-04-01
NO830527L (no) 1983-09-05
EP0087629B1 (en) 1986-01-15
JPH0314312B2 (da) 1991-02-26
IL67940A (en) 1986-02-28
FI79308C (fi) 1989-12-11
DE3361812D1 (en) 1986-02-27
IE830331L (en) 1983-09-03
IL67940A0 (en) 1983-06-15
FI830523L (fi) 1983-09-04

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