DK69190A - Mutanter af urinaer plasminogenaktivator, deres fremstilling af anvendelse - Google Patents

Mutanter af urinaer plasminogenaktivator, deres fremstilling af anvendelse Download PDF

Info

Publication number
DK69190A
DK69190A DK069190A DK69190A DK69190A DK 69190 A DK69190 A DK 69190A DK 069190 A DK069190 A DK 069190A DK 69190 A DK69190 A DK 69190A DK 69190 A DK69190 A DK 69190A
Authority
DK
Denmark
Prior art keywords
urines
mutants
preparation
plasminogen activator
plasminogen
Prior art date
Application number
DK069190A
Other languages
English (en)
Other versions
DK69190D0 (da
Inventor
Eric Paul Paques
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK69190D0 publication Critical patent/DK69190D0/da
Publication of DK69190A publication Critical patent/DK69190A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK069190A 1989-03-17 1990-03-16 Mutanter af urinaer plasminogenaktivator, deres fremstilling af anvendelse DK69190A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89104762A EP0387380A1 (en) 1989-03-17 1989-03-17 Mutants of urinary plasminogen activator, their production and use

Publications (2)

Publication Number Publication Date
DK69190D0 DK69190D0 (da) 1990-03-16
DK69190A true DK69190A (da) 1990-09-18

Family

ID=8201098

Family Applications (1)

Application Number Title Priority Date Filing Date
DK069190A DK69190A (da) 1989-03-17 1990-03-16 Mutanter af urinaer plasminogenaktivator, deres fremstilling af anvendelse

Country Status (7)

Country Link
EP (1) EP0387380A1 (da)
JP (1) JPH02283282A (da)
KR (1) KR900014592A (da)
AU (1) AU628491B2 (da)
CA (1) CA2012346A1 (da)
DK (1) DK69190A (da)
PT (1) PT93439A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4203545A1 (de) * 1992-02-07 1993-08-12 Behringwerke Ag Spezifische antikoerper gegen aktivierte plaettchen, ihre herstellung und ihre verwendung in diagnose und therapie
US5472692A (en) * 1993-07-02 1995-12-05 New England Deaconess Hospital Corporation Pro-urokinase mutants
GB9415167D0 (en) 1994-07-27 1994-09-14 Springer Caroline J Improvements relating to cancer therapy
JP4546578B2 (ja) 2006-07-05 2010-09-15 カタリスト・バイオサイエンシーズ・インコーポレイテッド プロテアーゼスクリーニング方法およびそれにより同定されるプロテアーゼ
AU2013202890B2 (en) * 2006-07-05 2016-08-11 Vertex Pharmaceuticals Incorporated Protease screening methods and proteases identified thereby
US11613744B2 (en) 2018-12-28 2023-03-28 Vertex Pharmaceuticals Incorporated Modified urokinase-type plasminogen activator polypeptides and methods of use
PE20211664A1 (es) * 2018-12-28 2021-08-26 Catalyst Biosciences Inc Polipeptidos de activador de plasminogeno, tipo urocinasa, modificados y metodos de uso

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0266032A1 (en) * 1986-08-29 1988-05-04 Beecham Group Plc Modified fibrinolytic enzyme
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.

Also Published As

Publication number Publication date
AU628491B2 (en) 1992-09-17
JPH02283282A (ja) 1990-11-20
AU5134990A (en) 1990-09-20
CA2012346A1 (en) 1990-09-17
EP0387380A1 (en) 1990-09-19
PT93439A (pt) 1990-11-07
DK69190D0 (da) 1990-03-16
KR900014592A (ko) 1990-10-24

Similar Documents

Publication Publication Date Title
DK306885A (da) Substituerede benzoatestere af 3-hydroxymorphinaner, deres fremstilling og anvendelse
FI894671A0 (fi) Reglerbar faestanordning.
DK424385D0 (da) Aminobenzopyranoner, deres fremstilling og anvendelse som antipsychotiske og anxiolytiske midler
DE59001142D1 (de) Acetale von oxo-tetralinen und von oxo-indanen.
DK229189A (da) Modificerede blokpolymerisater, deres fremstilling og anvendelse
DK69190D0 (da) Mutanter af urinaer plasminogenaktivator, deres fremstilling af anvendelse
DK130390A (da) Praeparat af i prokaryonter udtrykt plasminogenaktivator
DK289585D0 (da) Arylderivater af heterobicycliske forbindelser, deres farmaceutiske anvendelse og deres fremstilling
DK579089D0 (da) Renin-inhiberende urinstofderivater af dipeptider, deres fremstilling og anvendelse
FI920423A0 (fi) Foerbaettringar i skaeranordning.
DK300488D0 (da) Mono- og polyhydroxyacylderivater af polyoxygenerede labdaner, deres fremstilling og anvendelse
DK114589D0 (da) Alkoxy- og alkylaminocarbonylalkylphospholipider, geometriske isomere og optiske antipoder deraf, deres fremstilling og anvendelse
DK0409321T3 (da) Fremgangsmåde til fremstilling af delta-lactoner
DK564685A (da) Derivater af antibiotika af pluramycin-gruppen, deres fremstilling og anvendelse
DK0411624T3 (da) Saccharidderivater af protocatechualdehyl
DK626984D0 (da) Estere af cephalosporinderivater, deres fremstilling og anvendelse
DK120989A (da) 1-carbonylderivater af 4-aryl-4-aryloxypiperidiner, deres fremstilling og anvendelse
DK233689A (da) Fremstilling af 2,3-dideoxynukleosider
DK0388665T3 (da) Substituerede N-hydroxypyrazoler og N-hydroxytriazoler, fremgangsmåde til deres fremstilling og deres anvendelse til bekæmpelse af skadelige organismer
DK326789A (da) Fremstilling af homonojirimycin-derivater
DK338589D0 (da) Morpholinoderivater af rhodomyciner, deres fremstilling og anvendelse
DK18389D0 (da) Praeparat med insekticid virkning til impraegnering af traevaerk, murvaerk og lignende
DK199389D0 (da) Heterocykliske forbindelser, deres fremstilling og anvendelse
DK0402857T3 (da) Anvendelse af 17beta-cyclopropylamino-androsten-derivater
FI906365L (fi) Borsttvaettmaskin foer slaktdjur.

Legal Events

Date Code Title Description
ATS Application withdrawn