DK78888A - Arylpiperazinylalkylenphenyl-heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse - Google Patents

Arylpiperazinylalkylenphenyl-heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse

Info

Publication number
DK78888A
DK78888A DK078888A DK78888A DK78888A DK 78888 A DK78888 A DK 78888A DK 078888 A DK078888 A DK 078888A DK 78888 A DK78888 A DK 78888A DK 78888 A DK78888 A DK 78888A
Authority
DK
Denmark
Prior art keywords
arylpiperazinylalkylenphenyl
pharmaceutical preparations
heterocyclic compounds
preparations containing
heterocyclic
Prior art date
Application number
DK078888A
Other languages
English (en)
Other versions
DK170878B1 (da
DK78888D0 (da
Inventor
Iii John Adams Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK78888D0 publication Critical patent/DK78888D0/da
Publication of DK78888A publication Critical patent/DK78888A/da
Application granted granted Critical
Publication of DK170878B1 publication Critical patent/DK170878B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK078888A 1987-02-17 1988-02-16 Piperazinalkylenphenyl-heterocycliske forbindelser og farmaceutiske præparater indeholdende disse DK170878B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8700340 1987-02-17
US8700340 1987-02-17

Publications (3)

Publication Number Publication Date
DK78888D0 DK78888D0 (da) 1988-02-16
DK78888A true DK78888A (da) 1988-08-18
DK170878B1 DK170878B1 (da) 1996-02-26

Family

ID=22202287

Family Applications (1)

Application Number Title Priority Date Filing Date
DK078888A DK170878B1 (da) 1987-02-17 1988-02-16 Piperazinalkylenphenyl-heterocycliske forbindelser og farmaceutiske præparater indeholdende disse

Country Status (30)

Country Link
EP (1) EP0279598B1 (da)
JP (1) JPH0699405B2 (da)
KR (1) KR900004126B1 (da)
CN (1) CN1015627B (da)
AP (1) AP88A (da)
AR (1) AR245125A1 (da)
AT (1) ATE94537T1 (da)
AU (1) AU583761B2 (da)
CA (1) CA1312080C (da)
CS (1) CS272783B2 (da)
DD (1) DD272080A5 (da)
DE (1) DE3884007T2 (da)
DK (1) DK170878B1 (da)
EG (1) EG18635A (da)
ES (1) ES2058249T3 (da)
FI (1) FI91752C (da)
HU (1) HU207731B (da)
IE (1) IE61258B1 (da)
IL (1) IL85368A0 (da)
IN (1) IN171858B (da)
MA (1) MA21183A1 (da)
MX (1) MX174210B (da)
MY (1) MY103210A (da)
NO (1) NO170582C (da)
NZ (1) NZ223530A (da)
PL (1) PL157118B1 (da)
PT (1) PT86766B (da)
SU (1) SU1634136A3 (da)
YU (1) YU46624B (da)
ZA (1) ZA881064B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
SE8803429D0 (sv) * 1988-09-28 1988-09-28 Pharmacia Ab Novel pyridyl- and pyrimidyl derivatives
US5166156A (en) * 1989-12-20 1992-11-24 Adir Et Compagnie Naphthyl piperazines useful as 5-HT1A receptor ligands
US5166157A (en) * 1989-12-20 1992-11-24 Adir Et Compagnie Naphthyl piperazines useful as 5-HT1A receptor ligands
FR2655988B1 (fr) * 1989-12-20 1994-05-20 Adir Cie Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5162324A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie Naphyl piperazines useful as 5-HT1A receptor ligands
US5162321A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie 1-naphthyl piperazines useful as 5-HT1A receptor ligands
ES2157442T3 (es) * 1995-06-06 2001-08-16 Aventis Pharma Inc Derivados de benzoisoxazol y de indazol, utilizados como agentes neurolepticos.
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
US6288091B1 (en) 1995-12-29 2001-09-11 Boehringer Ingelheim Ltd. Antiherpes virus compounds and methods for their preparation and use
NZ331104A (en) * 1995-12-29 2000-03-27 Boehringer Ingelheim Ca Ltd Phenyl thiazole derivatives that inhibit herpes replication by inhibiting the herpes helicase primase enzyme complex
WO1999001420A1 (en) 1997-07-03 1999-01-14 Taito Co., Ltd. Process for the preparation of 2-aminomalonic acid derivatives and intermediates used in the process
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2927924A (en) * 1958-04-03 1960-03-08 Lilly Co Eli Novel phenethyl-substituted piperazines
FR1300728A (da) * 1959-10-20 1962-07-02
DE1695410A1 (de) * 1967-04-20 1971-04-08 Merck Patent Gmbh Verfahren zur Herstellung von 1-(Thiazolyl-5-alkyl)-4-(pyridyl-2)-piperazinen
JPS5910675B2 (ja) * 1976-03-22 1984-03-10 ウェルファイド株式会社 アラルキルアミン誘導体
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物

Also Published As

Publication number Publication date
MX174210B (es) 1994-04-28
KR900004126B1 (ko) 1990-06-16
PT86766A (pt) 1988-03-01
IE880420L (en) 1988-08-17
MY103210A (en) 1993-05-29
MX10428A (es) 1993-09-01
PT86766B (pt) 1992-05-29
CA1312080C (en) 1992-12-29
ZA881064B (en) 1989-09-27
PL157118B1 (pl) 1992-04-30
EP0279598A3 (en) 1989-07-26
NZ223530A (en) 1990-07-26
HUT50334A (en) 1990-01-29
FI880716A7 (fi) 1988-08-18
YU30388A (en) 1989-10-31
CS96488A2 (en) 1990-04-11
NO170582C (no) 1992-11-04
DK170878B1 (da) 1996-02-26
AP8800082A0 (en) 1988-02-01
JPH0699405B2 (ja) 1994-12-07
DE3884007D1 (de) 1993-10-21
FI880716A0 (fi) 1988-02-16
EP0279598B1 (en) 1993-09-15
NO170582B (no) 1992-07-27
NO880667L (no) 1988-08-18
EP0279598A2 (en) 1988-08-24
CN1015627B (zh) 1992-02-26
EG18635A (en) 1994-04-30
YU46624B (sh) 1994-01-20
AU1174088A (en) 1988-08-18
NO880667D0 (no) 1988-02-16
AP88A (en) 1990-06-06
CS272783B2 (en) 1991-02-12
AR245125A1 (es) 1993-12-30
JPS63216875A (ja) 1988-09-09
SU1634136A3 (ru) 1991-03-07
MA21183A1 (fr) 1988-10-01
HU207731B (en) 1993-05-28
DE3884007T2 (de) 1994-01-20
ATE94537T1 (de) 1993-10-15
IL85368A0 (en) 1988-07-31
CN88100986A (zh) 1988-09-21
FI91752C (fi) 1994-08-10
PL270653A1 (en) 1988-12-08
DD272080A5 (de) 1989-09-27
IE61258B1 (en) 1994-10-19
IN171858B (da) 1993-01-23
AU583761B2 (en) 1989-05-04
FI91752B (fi) 1994-04-29
ES2058249T3 (es) 1994-11-01
KR880009964A (ko) 1988-10-06
DK78888D0 (da) 1988-02-16

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