DK80989A - Anvendelse af quinolizin- og quinolizinon-derivater ved fremstilling af laegemidler - Google Patents

Anvendelse af quinolizin- og quinolizinon-derivater ved fremstilling af laegemidler

Info

Publication number
DK80989A
DK80989A DK080989A DK80989A DK80989A DK 80989 A DK80989 A DK 80989A DK 080989 A DK080989 A DK 080989A DK 80989 A DK80989 A DK 80989A DK 80989 A DK80989 A DK 80989A
Authority
DK
Denmark
Prior art keywords
derivatives
quinolizinon
quinolizin
preparation
medicinal products
Prior art date
Application number
DK080989A
Other languages
English (en)
Other versions
DK175643B1 (da
DK80989D0 (da
Inventor
Maurice W Gittos
Francis P Miller
Stephen M Sorensen
John R Fozard
Paul Moser
Michael G Palfreyman
Hsien C Cheng
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP88400415A external-priority patent/EP0329902A1/en
Priority claimed from EP88400417A external-priority patent/EP0329904A1/en
Priority claimed from EP88400418A external-priority patent/EP0329905A1/en
Priority claimed from EP88400416A external-priority patent/EP0329903A1/en
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK80989D0 publication Critical patent/DK80989D0/da
Publication of DK80989A publication Critical patent/DK80989A/da
Application granted granted Critical
Publication of DK175643B1 publication Critical patent/DK175643B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198900809A 1988-02-23 1989-02-22 Anvendelse af quinolizin- og quinolizinon-derivater ved fremstilling af lægemidler DK175643B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
EP88400415A EP0329902A1 (en) 1988-02-23 1988-02-23 Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of psychosis
EP88400416 1988-02-23
EP88400417A EP0329904A1 (en) 1988-02-23 1988-02-23 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety
EP88400418A EP0329905A1 (en) 1988-02-23 1988-02-23 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for increasing gastric motility
EP88400418 1988-02-23
EP88400416A EP0329903A1 (en) 1988-02-23 1988-02-23 Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of glaucoma
EP88400415 1988-02-23
EP88400417 1988-02-23
US18563188A 1988-04-26 1988-04-26
US18563188 1988-04-26

Publications (3)

Publication Number Publication Date
DK80989D0 DK80989D0 (da) 1989-02-22
DK80989A true DK80989A (da) 1989-08-24
DK175643B1 DK175643B1 (da) 2005-01-03

Family

ID=27513624

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900809A DK175643B1 (da) 1988-02-23 1989-02-22 Anvendelse af quinolizin- og quinolizinon-derivater ved fremstilling af lægemidler

Country Status (10)

Country Link
EP (1) EP0329932B1 (da)
JP (1) JPH02288880A (da)
KR (1) KR890013018A (da)
AT (1) ATE129153T1 (da)
AU (1) AU624115B2 (da)
DE (1) DE68924545T2 (da)
DK (1) DK175643B1 (da)
ES (1) ES2080727T3 (da)
GR (1) GR3018299T3 (da)
IE (1) IE72504B1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0669963B2 (ja) * 1989-04-21 1994-09-07 サンド・アクチエンゲゼルシャフト ５ｈｔ▲下３▼受容体拮抗薬の治療的用途
EP0492020A1 (en) * 1990-12-21 1992-07-01 Merrell Dow Pharmaceuticals Inc. Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds for treating cognitive disorders
US5508287A (en) * 1992-02-24 1996-04-16 Merrell Pharmaceuticals Inc. 2,6-methano-2H-quinolizin derivative as 5-HT3 -receptor antagonist
KR100287933B1 (ko) * 1992-02-24 2001-05-02 슈테펜엘.네스비트 5-ht3-수용체 길항제로서의 2,6-메타노-2h-퀴놀리진 유도체,이의 제조방법 및 이를 포함하는 약제학적 조성물
EP2129672B1 (en) * 2007-03-23 2011-05-18 Abbott Laboratories Azaadamantane ester and carbamate derivatives and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
DE3429830A1 (de) * 1983-08-26 1985-03-07 Sandoz-Patent-GmbH, 7850 Lörrach Automatische carbonsaeure- und sulfonsaeureester oder -amide
DE3445377A1 (de) * 1983-12-23 1985-07-04 Sandoz-Patent-GmbH, 7850 Lörrach Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen
AU583343B2 (en) * 1985-01-23 1989-04-27 Glaxo Group Limited Heterocyclic compounds
EP0385517B1 (en) * 1985-03-14 1993-04-14 BEECHAM GROUP plc Medicaments for the treatment of emesis
GB8525913D0 (en) * 1985-10-21 1985-11-27 Beecham Group Plc Compounds
GB8511988D0 (en) * 1985-05-11 1985-06-19 Beecham Group Plc Compounds
GB8520616D0 (en) * 1985-08-16 1985-09-25 Beecham Group Plc Compounds
GB8523211D0 (en) * 1985-09-19 1985-10-23 Beecham Group Plc Compounds
EP0220011A3 (en) * 1985-10-12 1990-01-03 Beecham Group Plc Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia
US4910193A (en) * 1985-12-16 1990-03-20 Sandoz Ltd. Treatment of gastrointestinal disorders
ZA878096B (en) * 1986-11-03 1988-04-26 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one and related compounds
EP0330788A1 (en) * 1988-03-01 1989-09-06 Merrell Dow Pharmaceuticals Inc. Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia

Also Published As

Publication number Publication date
EP0329932A2 (en) 1989-08-30
IE72504B1 (en) 1997-04-23
DK175643B1 (da) 2005-01-03
DE68924545D1 (de) 1995-11-23
ATE129153T1 (de) 1995-11-15
EP0329932B1 (en) 1995-10-18
JPH02288880A (ja) 1990-11-28
KR890013018A (ko) 1989-09-20
AU3021489A (en) 1989-08-24
DE68924545T2 (de) 1996-03-21
DK80989D0 (da) 1989-02-22
IE890564L (en) 1989-08-23
AU624115B2 (en) 1992-06-04
GR3018299T3 (en) 1996-03-31
EP0329932A3 (en) 1992-08-05
ES2080727T3 (es) 1996-02-16

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Legal Events

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