DK83981A - 5-q-(3,4!-bipyridin)-6-(1h) on og fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden - Google Patents

5-q-(3,4!-bipyridin)-6-(1h) on og fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden

Info

Publication number
DK83981A
DK83981A DK83981A DK83981A DK83981A DK 83981 A DK83981 A DK 83981A DK 83981 A DK83981 A DK 83981A DK 83981 A DK83981 A DK 83981A DK 83981 A DK83981 A DK 83981A
Authority
DK
Denmark
Prior art keywords
procedure
bipyridine
preparing
Prior art date
Application number
DK83981A
Other languages
English (en)
Other versions
DK171253B1 (da
Inventor
K O Gelotte
C J Opalka
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK83981A publication Critical patent/DK83981A/da
Application granted granted Critical
Publication of DK171253B1 publication Critical patent/DK171253B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK083981A 1980-02-26 1981-02-25 Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on DK171253B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12480880 1980-02-26
US06/124,808 US4264609A (en) 1980-02-26 1980-02-26 N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic

Publications (2)

Publication Number Publication Date
DK83981A true DK83981A (da) 1981-08-27
DK171253B1 DK171253B1 (da) 1996-08-12

Family

ID=22416880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK083981A DK171253B1 (da) 1980-02-26 1981-02-25 Fremgangsmåde til fremstilling af 5-Q-[3,4-bipyri din]-6(1H)-on

Country Status (28)

Country Link
US (1) US4264609A (da)
JP (1) JPS56128758A (da)
KR (2) KR840002067B1 (da)
AR (1) AR230630A1 (da)
AT (2) AT380237B (da)
AU (1) AU541644B2 (da)
BE (1) BE887663A (da)
CA (1) CA1128523A (da)
CH (1) CH647509A5 (da)
DE (1) DE3107306A1 (da)
DK (1) DK171253B1 (da)
ES (1) ES499776A1 (da)
FI (1) FI76787C (da)
FR (1) FR2476646A1 (da)
GB (1) GB2070600B (da)
HK (1) HK71789A (da)
IE (1) IE51696B1 (da)
IL (1) IL62161A (da)
IT (1) IT1210992B (da)
LU (1) LU83169A1 (da)
MX (1) MX6908E (da)
NL (1) NL192109C (da)
NO (1) NO156689C (da)
NZ (1) NZ196282A (da)
PH (2) PH19904A (da)
PT (1) PT72573B (da)
SE (2) SE437514B (da)
ZA (1) ZA811124B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3685840D1 (de) 1985-04-30 1992-08-06 Dresden Arzneimittel 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones

Also Published As

Publication number Publication date
SE8101205L (sv) 1981-08-27
FI76787B (fi) 1988-08-31
FI76787C (fi) 1988-12-12
KR840002067B1 (ko) 1984-11-09
NL8100922A (nl) 1981-09-16
CH647509A5 (fr) 1985-01-31
IT1210992B (it) 1989-09-29
GB2070600B (en) 1984-07-11
BE887663A (fr) 1981-08-25
ATA88581A (de) 1985-09-15
CA1128523A (en) 1982-07-27
AU541644B2 (en) 1985-01-17
KR840002066B1 (ko) 1984-11-09
IL62161A0 (en) 1981-03-31
NO156689C (no) 1987-11-04
GB2070600A (en) 1981-09-09
DE3107306C2 (da) 1990-11-29
IE810397L (en) 1981-08-26
NO156689B (no) 1987-07-27
ATA305683A (de) 1985-09-15
ES499776A1 (es) 1984-06-16
SE8402727L (sv) 1984-05-21
SE8402727D0 (sv) 1984-05-21
PH19904A (en) 1986-08-13
NL192109C (nl) 1997-02-04
JPS56128758A (en) 1981-10-08
NO810639L (no) 1981-08-27
ZA811124B (en) 1982-03-31
MX6908E (es) 1986-11-07
PT72573B (en) 1982-02-12
AT380237B (de) 1986-04-25
PH17145A (en) 1984-06-04
DK171253B1 (da) 1996-08-12
IE51696B1 (en) 1987-02-18
HK71789A (en) 1989-09-14
DE3107306A1 (de) 1981-12-17
SE452764B (sv) 1987-12-14
FR2476646A1 (fr) 1981-08-28
AT380236B (de) 1986-04-25
AR230630A1 (es) 1984-05-31
FR2476646B1 (da) 1984-08-17
AU6748781A (en) 1981-09-03
LU83169A1 (fr) 1981-09-11
IL62161A (en) 1984-06-29
NZ196282A (en) 1983-12-16
NL192109B (nl) 1996-10-01
PT72573A (pt) 1981-03-01
FI810582L (fi) 1981-08-27
SE437514B (sv) 1985-03-04
KR830005143A (ko) 1983-08-03
JPH0141626B2 (da) 1989-09-06
IT8119952A0 (it) 1981-02-24
US4264609A (en) 1981-04-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired