DK8591A - Interleukin-l inhibitor - Google Patents

Interleukin-l inhibitor Download PDF

Info

Publication number
DK8591A
DK8591A DK008591A DK8591A DK8591A DK 8591 A DK8591 A DK 8591A DK 008591 A DK008591 A DK 008591A DK 8591 A DK8591 A DK 8591A DK 8591 A DK8591 A DK 8591A
Authority
DK
Denmark
Prior art keywords
interleukin
inhibitor
Prior art date
Application number
DK008591A
Other languages
English (en)
Other versions
DK172763B1 (da
DK8591D0 (da
Inventor
Charles H Hannum
Stephen P Eisenberg
Robert C Thompson
William P Arend
Fenneke G Joslin
Andreas Sommer
Original Assignee
Synergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synergen Inc filed Critical Synergen Inc
Publication of DK8591A publication Critical patent/DK8591A/da
Publication of DK8591D0 publication Critical patent/DK8591D0/da
Application granted granted Critical
Publication of DK172763B1 publication Critical patent/DK172763B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK199100085A 1988-05-27 1991-01-18 Isoleret interleukin-1 (IL-1) inhibitor eller forstadiepolypeptid dertil, isoleret DNA-molekyle, som koder derfor, vektor o DK172763B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US19991588A 1988-05-27 1988-05-27
US19991588 1988-05-27
US23871388A 1988-08-31 1988-08-31
US23871388 1988-08-31
US26653188A 1988-11-03 1988-11-03
US26653188 1988-11-03
PCT/US1989/002275 WO1989011540A1 (en) 1988-05-27 1989-05-25 Interleukin-1 inhibitors
US8902275 1989-05-25

Publications (3)

Publication Number Publication Date
DK8591A true DK8591A (da) 1991-01-18
DK8591D0 DK8591D0 (da) 1991-01-18
DK172763B1 DK172763B1 (da) 1999-07-05

Family

ID=27394086

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199100085A DK172763B1 (da) 1988-05-27 1991-01-18 Isoleret interleukin-1 (IL-1) inhibitor eller forstadiepolypeptid dertil, isoleret DNA-molekyle, som koder derfor, vektor o

Country Status (9)

Country Link
JP (2) JP3192651B2 (da)
KR (1) KR970002917B1 (da)
BR (1) BR8907457A (da)
DK (1) DK172763B1 (da)
FI (2) FI109206B (da)
HU (3) HU9803037D0 (da)
NO (2) NO316122B1 (da)
OA (1) OA09631A (da)
WO (1) WO1989011540A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075222A (en) 1988-05-27 1991-12-24 Synergen, Inc. Interleukin-1 inhibitors
US6159460A (en) * 1988-05-27 2000-12-12 Amgen Inc. Method for treating interleukin-1 mediated diseases
US6858409B1 (en) 1988-05-27 2005-02-22 Amgen Inc. Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
US5872095A (en) * 1990-05-01 1999-02-16 Chiron Corporation IL-1 receptor antagonists medicaments
EP0534978B1 (en) * 1990-05-01 1999-03-24 Chiron Corporation Interleukin-1 antagonist and uses thereof
US5932537A (en) * 1990-10-09 1999-08-03 Chiron Corporation Method for attenuating a cellular response to IL-1
US5747444A (en) * 1990-10-09 1998-05-05 Chiron Corporation Method of treating graft-versus-host disease
ZA921120B (en) 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US20030103978A1 (en) 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
WO2003035048A2 (en) * 2001-10-26 2003-05-01 Novartis Ag Methods for the treatment of osteoarthritis and compositions thereof
EP2314316A1 (en) 2002-04-05 2011-04-27 Amgen, Inc Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
CA2574881C (en) 2004-08-04 2013-01-08 Amgen Inc. Antibodies to dkk-1
RS56743B1 (sr) 2007-08-21 2018-03-30 Amgen Inc Humani c-fms antigen vezujući proteini
CA2737056C (en) * 2008-09-12 2018-10-30 Xbiotech Inc. Targeting pathogenic monocytes
WO2012025910A1 (en) 2010-08-26 2012-03-01 Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional METHODS OF DIAGNOSIS AND TREATMENT OF OSTEOARTHRITIS AT EARLY STAGES USING INTERLEUKIN IL-1ß AS EARLY BIOMARKER OF THE DISEASE
WO2012122985A1 (en) 2011-03-14 2012-09-20 University Of Copenhagen Antagonists of the interleukin- 1 receptor
CN103492416A (zh) 2011-04-15 2014-01-01 默克专利股份公司 用于癌症中使用的抗il-1r1抑制剂
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
WO2015087187A1 (en) 2013-12-10 2015-06-18 Rinat Neuroscience Corp. Anti-sclerostin antibodies
AU2017229575A1 (en) 2016-03-08 2018-09-27 Janssen Biotech, Inc. GITR antibodies, methods, and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3014099B2 (ja) * 1987-08-26 2000-02-28 バイオジェン インコーポレイテッド 生物的材料、生物的材料の生産およびこの種の材料の治療への使用方法

Also Published As

Publication number Publication date
HU215434B (hu) 1999-04-28
NO905090D0 (no) 1990-11-23
DK172763B1 (da) 1999-07-05
AU633831B2 (en) 1993-02-11
FI20020545L (fi) 2002-03-21
KR970002917B1 (ko) 1997-03-12
JP3192651B2 (ja) 2001-07-30
HU893412D0 (en) 1991-05-28
NO20014783D0 (no) 2001-10-01
HU9803037D0 (en) 1999-11-29
NO905090L (no) 1991-01-28
NO316122B1 (no) 2003-12-15
NO316917B1 (no) 2004-06-21
JPH03505279A (ja) 1991-11-21
AU3746989A (en) 1989-12-12
FI905812A0 (fi) 1990-11-26
JP2001029093A (ja) 2001-02-06
OA09631A (en) 1993-04-30
DK8591D0 (da) 1991-01-18
NO20014783L (no) 1991-01-28
FI109206B (fi) 2002-06-14
HU222810B1 (hu) 2003-11-28
FI20020545A7 (fi) 2002-03-21
BR8907457A (pt) 1991-04-02
WO1989011540A1 (en) 1989-11-30

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
AGE Re-establishment of rights: approved
B1 Patent granted (law 1993)
PUP Patent expired