DK9390A - Kondenserede benzapiner - Google Patents

Kondenserede benzapiner Download PDF

Info

Publication number: DK9390A
Authority: DK; Denmark
Prior art keywords: benzapines; condensed; compounds; transisomeric; benzazepines
Prior art date: 1987-07-15

Application number

DK009390A

Other languages

English (en)

Other versions

DK162889B (da

DK162889C (da

DK9390D0 (da

Inventor

Joel Gilbert Berger

Wei Kong Chang

Elijah Herman Gold

John Welch Clader

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-15

Filing date

1990-01-12

Publication date

1990-03-12

1990-01-12 Application filed by Schering Corp filed Critical Schering Corp

1990-01-12 Publication of DK9390D0 publication Critical patent/DK9390D0/da

1990-03-12 Publication of DK9390A publication Critical patent/DK9390A/da

1991-12-23 Publication of DK162889B publication Critical patent/DK162889B/da

1992-05-11 Application granted granted Critical

1992-05-11 Publication of DK162889C publication Critical patent/DK162889C/da

Links

150000001875 compounds Chemical class 0.000 abstract 2
206010020772 Hypertension Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
150000008038 benzoazepines Chemical class 0.000 abstract 1
230000036407 pain Effects 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
229940124550 renal vasodilator Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Electroluminescent Light Sources (AREA)
Luminescent Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

DK009390A 1987-07-15 1990-01-12 Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater DK162889C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US8701636		1987-07-15
PCT/US1987/001636 WO1989000561A1 (en)	1987-07-15	1987-07-15	Fused benzazepines
EP87110253A EP0299101B1 (en)	1987-07-15	1987-07-16	Fused benzazepines
EP87110253		1987-07-16

Publications (4)

Publication Number	Publication Date
DK9390D0 DK9390D0 (da)	1990-01-12
DK9390A true DK9390A (da)	1990-03-12
DK162889B DK162889B (da)	1991-12-23
DK162889C DK162889C (da)	1992-05-11

Family

ID=26108265

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK009390A DK162889C (da)	1987-07-15	1990-01-12	Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater

Country Status (13)

Country	Link
EP (2)	EP0363353B1 (da)
JP (1)	JPH0678317B2 (da)
AT (1)	ATE78467T1 (da)
AU (1)	AU617651B2 (da)
DE (1)	DE3780649T2 (da)
DK (1)	DK162889C (da)
ES (1)	ES2043623T3 (da)
FI (1)	FI93212C (da)
GR (1)	GR3006671T3 (da)
HU (1)	HU203537B (da)
NO (1)	NO177264C (da)
WO (1)	WO1989000561A1 (da)
ZA (1)	ZA875183B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4973586A (en) *	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
PL168408B1 (pl) *	1989-08-03	1996-02-29	Smithkline Beecham Biolog	Sposób wytwarzania stransformowanego mikroorganizmu PL
FI923458A0 (fi) *	1990-02-02	1992-07-31	Schering Corp	4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning.
JPH07137816A (ja) *	1993-11-15	1995-05-30	Tokai Univ	地下空洞内貯蔵装置
JP4555685B2 (ja) *	2002-08-29	2010-10-06	シェーリングコーポレイション	肥満およびｃｎｓ障害の処置のための選択的ｄ１／ｄ５レセプターアンタゴニスト
EP1646623A2 (en) *	2003-05-22	2006-04-19	Schering Corporation	5-h-benzo[d]naphth[2,1-b]azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3393192A (en) *	1965-04-26	1968-07-16	Schering Corp	Novel benzazepines
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US4680298A (en) *	1983-05-31	1987-07-14	Schering Corporation	Tricyclic anti-allergy and use as anti-inflammatory agents
EP0254737B1 (en) *	1986-01-16	1990-07-25	Schering Corporation	Fused benzazepines

1987
- 1987-07-15 AU AU80378/87A patent/AU617651B2/en not_active Ceased
- 1987-07-15 WO PCT/US1987/001636 patent/WO1989000561A1/en not_active Ceased
- 1987-07-15 ZA ZA875183A patent/ZA875183B/xx unknown
- 1987-07-15 HU HU8552A patent/HU203537B/hu not_active IP Right Cessation
- 1987-07-15 EP EP87906614A patent/EP0363353B1/en not_active Expired - Lifetime
- 1987-07-15 DE DE8787906614T patent/DE3780649T2/de not_active Expired - Lifetime
- 1987-07-15 JP JP62506016A patent/JPH0678317B2/ja not_active Expired - Lifetime
- 1987-07-15 AT AT87906614T patent/ATE78467T1/de not_active IP Right Cessation
- 1987-07-16 EP EP87110253A patent/EP0299101B1/en not_active Expired - Lifetime
- 1987-07-16 ES ES87110253T patent/ES2043623T3/es not_active Expired - Lifetime
1990
- 1990-01-12 NO NO900186A patent/NO177264C/no unknown
- 1990-01-12 DK DK009390A patent/DK162889C/da active
- 1990-01-12 FI FI900175A patent/FI93212C/fi not_active IP Right Cessation
1992
- 1992-12-24 GR GR920403109T patent/GR3006671T3/el unknown

Also Published As

Publication number	Publication date
FI900175A0 (fi)	1990-01-12
ES2043623T3 (es)	1994-01-01
DE3780649T2 (de)	1992-12-10
HU203537B (en)	1991-08-28
EP0299101B1 (en)	1992-09-23
JPH0678317B2 (ja)	1994-10-05
GR3006671T3 (da)	1993-06-30
NO900186D0 (no)	1990-01-12
EP0363353A1 (en)	1990-04-18
NO177264B (no)	1995-05-08
NO177264C (no)	1995-08-16
NO900186L (no)	1990-01-12
AU8037887A (en)	1989-02-13
JPH02504629A (ja)	1990-12-27
EP0299101A1 (en)	1989-01-18
FI93212C (fi)	1995-03-10
ZA875183B (en)	1988-04-08
ATE78467T1 (de)	1992-08-15
WO1989000561A1 (en)	1989-01-26
FI93212B (fi)	1994-11-30
DK162889B (da)	1991-12-23
DK162889C (da)	1992-05-11
DK9390D0 (da)	1990-01-12
EP0363353B1 (en)	1992-07-22
AU617651B2 (en)	1991-12-05
DE3780649D1 (de)	1992-08-27

Publication	Publication Date	Title
EA199800946A1 (ru)	1999-06-24	Концентрированный препарат антител
DK442788A (da)	1988-10-07	Fremgangsmaade og praeparat til behandling af non-ige-medierede lidelser
DE68903846D1 (de)	1993-01-28	Neue galenische form von fenofibrat.
FI875209L (fi)	1988-05-28	Galeniskt preparat.
DE3784157D1 (de)	1993-03-25	Modifizierte succinimide.
NO875045D0 (no)	1987-12-03	Fremgangsmaate for fremstilling av topiske preparater for behandling av akne.
DK479087A (da)	1987-09-14	Kondenserede benzazepiner
NO161899C (no)	1989-10-11	Freseverktoey for trebearbeidning.
FI872630A0 (fi)	1987-06-12	Farmaceutiska kompositioner foer utvaertes bruk, vilka laett penetrerar huden.
FI873841A7 (fi)	1988-03-09	Cis-platina-komplex, foerfarande foer deras framstaellning och dessa foereningar innehaollande farmaceutisk produkt.
FI883561L (fi)	1989-01-31	Spaonskaerare.
DE3689232D1 (de)	1993-12-02	Ionenquelle.
ES2088965T3 (es)	1996-10-01	Derivados de rodanina aril-sustituidos.
NL960005I1 (nl)	1996-09-02	Optisch zuivere verbinding, en werkwijze voor de bereiding daarvan.
DE3881579D1 (de)	1993-07-15	Ionenquelle.
DK5384A (da)	1984-01-05	Cycloaliphatiske farmaceutiske forbindelser
NO874193D0 (no)	1987-10-06	Farmasoeytiske preparater.
FI850304L (fi)	1985-07-26	Indolofenathridiner.
FI883370A7 (fi)	1989-01-18	Vaakasuuntainen, voima-avusteinen nahanlevityspöytä
NO873213D0 (no)	1987-07-31	Fremgangsmaate for fremstilling av transdermale preparater.
NO900186D0 (no)	1990-01-12	Kondenserte benzazepiner.
DE3779675D1 (de)	1992-07-16	6-(disubstituiertes amino)carbapenam-verbindungen.
IT8705102A0 (it)	1987-01-13	Derivati di prolina.
DE69006704D1 (de)	1994-03-24	Trifunktionelle Polyoxyethylenediaminderivate.
NO903599L (no)	1990-08-15	Minoxidilgel.