DOP2006000060A - Compuestos de n-sulfonilaminofeniletil -2-fenoxiacetamida sustituida - Google Patents
Compuestos de n-sulfonilaminofeniletil -2-fenoxiacetamida sustituidaInfo
- Publication number
- DOP2006000060A DOP2006000060A DO2006000060A DO2006000060A DOP2006000060A DO P2006000060 A DOP2006000060 A DO P2006000060A DO 2006000060 A DO2006000060 A DO 2006000060A DO 2006000060 A DO2006000060 A DO 2006000060A DO P2006000060 A DOP2006000060 A DO P2006000060A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- alkyl
- alkoxy
- sulfonylaminofeniletile
- halogen atom
- compounds replaced
- Prior art date
Links
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 11
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 7
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 2
- -1 (C1-Cs) -sulfinyl Chemical group 0.000 abstract 2
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Esta invencion proporciona un compuesto de formula (I): en la que R' representa alquilo (C1-C6); R2 representa un atomo de hidrogeno, un atomo de halogeno, un grupo hidroxi, alquilo (Cl-C6), alcoxi (C1-C6), hidroxi-alquilo (C1-C6), alcoxi (C1-C6)-alquilo (C,1-C6) o halo-alquilo (C1-C6); R3 representa un atomo de halogeno, alquilo (C1-C6), alcoxi (Cl-C6), hidroxi-alcoxi (C1-C6), alcoxi (C1-C6)-alquilo (C1-C6), alcoxi (C1-C6)-alcoxi (C1-C6), haloalquilo (C1-C6), alquil (C1-Cs)-tio, alquil (C1-Cs)-sulfinilo, alquil (C1-C6) sulfonilo, [alquil (C1-C6)]NH- o [alquil (C1-C6)]2N-; R4 representa un itomo de halogeno, alquilo (C1-C6), haloalquilo (C1-C6), alcoxi (C1-C6), hidroxi-alcoxi (C1-C6, alcoxi (C1-C6)-alquilo (C1-C6, alcoxi (C1-C6)alcoxi (C1-C6), [alquil (C1-C6)]NH-, o [alquil (C1-C6)]2N-; R5 representa un atomo de halogeno, alquilo (C1-C5), alcoxi (C1-C6), hidroxi alcoxi (C1-C6), alcoxi (C1-Cs)-alquilo (C1-C6), alcoxi (C1-Cs)-alcoxi (C1-C6), haloalquilo (C1-C6), alquil (Cl-C6)-to, alquil (C1-C6)-sulfinilo, alquil (C1-C6) sulfonilo, [alquil (C1-C6)]NH-, [alquil (C1-C6)]2N-, H2N-alcoxi (C1-C6), alquil (C1- C6)-NH-alcoxi (C1-C6), [alquil (C1-C6)]2N-alcoxi (C1-C6), H2N-alcoxi (C1-C6)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66097805P | 2005-03-10 | 2005-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2006000060A true DOP2006000060A (es) | 2006-09-30 |
Family
ID=36297248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2006000060A DOP2006000060A (es) | 2005-03-10 | 2006-03-09 | Compuestos de n-sulfonilaminofeniletil -2-fenoxiacetamida sustituida |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7566739B2 (es) |
| EP (1) | EP1858865B1 (es) |
| JP (1) | JP4906839B2 (es) |
| AR (1) | AR052938A1 (es) |
| AT (1) | ATE443056T1 (es) |
| CA (1) | CA2600409C (es) |
| DE (1) | DE602006009231D1 (es) |
| DO (1) | DOP2006000060A (es) |
| ES (1) | ES2331153T3 (es) |
| GT (1) | GT200600107A (es) |
| MX (1) | MX2007011105A (es) |
| NL (1) | NL1031335C2 (es) |
| PE (1) | PE20061163A1 (es) |
| TW (1) | TW200700398A (es) |
| UY (1) | UY29412A1 (es) |
| WO (1) | WO2006095263A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0934061B3 (en) | 1996-07-24 | 2015-01-21 | Warner-Lambert Company LLC | Isobutylgaba and its derivatives for the treatment of pain |
| AU2006225496A1 (en) * | 2005-03-19 | 2006-09-28 | Amorepacific Corporation | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| WO2007120012A1 (en) * | 2006-04-19 | 2007-10-25 | Amorepacific Corporation | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| CA2658925C (en) | 2006-07-27 | 2015-07-14 | Amorepacific Corporation | Novel sulfonylamino acrylamide derivatives, isomer thereof,or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| WO2009096701A2 (en) | 2008-01-28 | 2009-08-06 | Amorepacific Corporation | Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| WO2009132050A2 (en) | 2008-04-21 | 2009-10-29 | Otonomy, Inc. | Auris formulations for treating otic diseases and conditions |
| US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
| JP5438103B2 (ja) | 2008-07-02 | 2014-03-12 | アモーレパシフィック コーポレイション | バニロイド受容体アンタゴニストとしての新規化合物、その異性体またはその薬学的に許容される塩、並びにそれを含む医薬組成物 |
| WO2010011605A2 (en) | 2008-07-21 | 2010-01-28 | Otonomy, Inc. | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| CN102762572A (zh) | 2010-02-01 | 2012-10-31 | 诺瓦提斯公司 | 作为CRF-1受体拮抗剂的吡唑并[5,1b]*唑衍生物 |
| EP2531490B1 (en) | 2010-02-02 | 2014-10-15 | Novartis AG | Cyclohexyl amide derivatives as crf receptor antagonists |
| NZ705225A (en) | 2010-07-16 | 2016-11-25 | Abbvie Bahamas Ltd | Process for preparing antiviral compounds |
| US8975443B2 (en) | 2010-07-16 | 2015-03-10 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| US8841487B2 (en) | 2010-07-16 | 2014-09-23 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| US9255074B2 (en) | 2010-07-16 | 2016-02-09 | Abbvie Inc. | Process for preparing antiviral compounds |
| EP3478269A4 (en) | 2016-06-29 | 2020-04-08 | Otonomy, Inc. | OTIC FORMULATIONS BASED ON TRIGLYCERIDES AND THEIR USES |
| EP3522881A4 (en) * | 2016-10-05 | 2020-05-27 | Afecta Pharmaceuticals, Inc. | HIGHLY MOBILE GROUP B1 PROTEIN INHIBITORS |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4810716A (en) | 1986-04-11 | 1989-03-07 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
| US5585388A (en) | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
| US6632815B2 (en) | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| CZ2002961A3 (cs) | 1999-09-17 | 2002-08-14 | Millennium Pharmaceuticals, Inc. | Benzamidy a příbuzné sloučeniny pro inhibici faktoru Xa |
| AU781880B2 (en) | 1999-09-17 | 2005-06-16 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| WO2001064642A2 (en) | 2000-02-29 | 2001-09-07 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| EP1311478B1 (en) * | 2000-08-21 | 2006-06-07 | Pacific Corporation | Novel (thio)urea compounds and the pharmaceutical compositions containing the same |
| NZ523882A (en) * | 2000-08-21 | 2004-11-26 | Pacific Corp | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
| CN1564809A (zh) | 2001-10-04 | 2005-01-12 | 诺瓦提斯公司 | 有机化合物 |
| US7229987B2 (en) | 2002-05-13 | 2007-06-12 | Eli Lilly And Company | Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes |
| KR100556158B1 (ko) * | 2002-10-17 | 2006-03-06 | (주) 디지탈바이오텍 | 신규 엔-하이드록시 티오우레아, 우레아 및 아미드계화합물 및 이를 함유하는 약제학적 조성물 |
| KR100707123B1 (ko) * | 2003-07-02 | 2007-04-16 | 그뤼넨탈 게엠베하 | 바닐로이드 수용체의 길항제로서 강력한 진통효과를나타내는 4-(메틸설포닐아미노)페닐 동족체 및 이를함유하는 약학적 조성물 |
| US20050085449A1 (en) | 2003-10-15 | 2005-04-21 | Dalton James T. | Haloacetamide and azide substituted compounds and methods of use thereof |
| CA2541894A1 (en) | 2003-10-24 | 2005-05-06 | Kissei Pharmaceutical Co., Ltd. | Amino alcohol derivative, medicinal composition containing the same, and use of these |
| CN101087771A (zh) * | 2004-11-10 | 2007-12-12 | 辉瑞大药厂 | 经取代n－磺酰基氨基苄基－2－苯氧基乙酰胺化合物 |
-
2006
- 2006-02-24 EP EP06710536A patent/EP1858865B1/en not_active Expired - Lifetime
- 2006-02-24 MX MX2007011105A patent/MX2007011105A/es active IP Right Grant
- 2006-02-24 CA CA2600409A patent/CA2600409C/en not_active Expired - Fee Related
- 2006-02-24 JP JP2008500290A patent/JP4906839B2/ja not_active Expired - Fee Related
- 2006-02-24 ES ES06710536T patent/ES2331153T3/es not_active Expired - Lifetime
- 2006-02-24 DE DE602006009231T patent/DE602006009231D1/de not_active Expired - Lifetime
- 2006-02-24 WO PCT/IB2006/000539 patent/WO2006095263A1/en not_active Ceased
- 2006-02-24 AT AT06710536T patent/ATE443056T1/de not_active IP Right Cessation
- 2006-03-08 AR ARP060100869A patent/AR052938A1/es unknown
- 2006-03-08 UY UY29412A patent/UY29412A1/es not_active Application Discontinuation
- 2006-03-08 PE PE2006000268A patent/PE20061163A1/es not_active Application Discontinuation
- 2006-03-09 DO DO2006000060A patent/DOP2006000060A/es unknown
- 2006-03-09 GT GT200600107A patent/GT200600107A/es unknown
- 2006-03-09 NL NL1031335A patent/NL1031335C2/nl not_active IP Right Cessation
- 2006-03-09 TW TW095108023A patent/TW200700398A/zh unknown
- 2006-03-10 US US11/372,706 patent/US7566739B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| UY29412A1 (es) | 2006-10-31 |
| DE602006009231D1 (de) | 2009-10-29 |
| MX2007011105A (es) | 2007-10-08 |
| TW200700398A (en) | 2007-01-01 |
| EP1858865A1 (en) | 2007-11-28 |
| EP1858865B1 (en) | 2009-09-16 |
| ATE443056T1 (de) | 2009-10-15 |
| ES2331153T3 (es) | 2009-12-22 |
| PE20061163A1 (es) | 2006-10-27 |
| WO2006095263A1 (en) | 2006-09-14 |
| US7566739B2 (en) | 2009-07-28 |
| AR052938A1 (es) | 2007-04-11 |
| CA2600409C (en) | 2011-07-05 |
| JP4906839B2 (ja) | 2012-03-28 |
| CA2600409A1 (en) | 2006-09-14 |
| NL1031335C2 (nl) | 2007-01-23 |
| US20060205980A1 (en) | 2006-09-14 |
| WO2006095263A8 (en) | 2007-11-08 |
| JP2008532994A (ja) | 2008-08-21 |
| NL1031335A1 (nl) | 2006-09-12 |
| GT200600107A (es) | 2006-12-26 |
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