DOP2009000132A - AKT ACTIVITY INHIBITORS - Google Patents
AKT ACTIVITY INHIBITORSInfo
- Publication number
- DOP2009000132A DOP2009000132A DO2009000132A DO2009000132A DOP2009000132A DO P2009000132 A DOP2009000132 A DO P2009000132A DO 2009000132 A DO2009000132 A DO 2009000132A DO 2009000132 A DO2009000132 A DO 2009000132A DO P2009000132 A DOP2009000132 A DO P2009000132A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- akt
- akt activity
- activity inhibitors
- compounds
- activity
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000001708 Protein Isoforms Human genes 0.000 abstract 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000005054 naphthyridines Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invención proporciona compuestos de naftiridina sustituidos que inhiben la actividad de la Akt. En particular, los compuestos descritos inhiben de manera selectiva una o dos de las isoformas de la Akt. La invención tambien proporciona composiciones que comprenden tales compuestos inhibidores y procedimientos de inhibición de la actividad de la Akt mediante la administración del compuesto a un paciente en necesidad de tratamiento de cáncer.The present invention provides substituted naphthyridine compounds that inhibit the activity of Akt. In particular, the compounds described selectively inhibit one or two of the isoforms of Akt. The invention also provides compositions comprising such inhibitor compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of cancer treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2009000132A DOP2009000132A (en) | 2009-06-05 | 2009-06-05 | AKT ACTIVITY INHIBITORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2009000132A DOP2009000132A (en) | 2009-06-05 | 2009-06-05 | AKT ACTIVITY INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2009000132A true DOP2009000132A (en) | 2009-08-15 |
Family
ID=44680891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2009000132A DOP2009000132A (en) | 2009-06-05 | 2009-06-05 | AKT ACTIVITY INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| DO (1) | DOP2009000132A (en) |
-
2009
- 2009-06-05 DO DO2009000132A patent/DOP2009000132A/en unknown
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