DOP2009000145A - DERIVATIVES OF 8-ETINYLXANTINE AS SELECTIVE A2A RECEIVER ANTAGONISTS - Google Patents

DERIVATIVES OF 8-ETINYLXANTINE AS SELECTIVE A2A RECEIVER ANTAGONISTS

Info

Publication number
DOP2009000145A
DOP2009000145A DO2009000145A DO2009000145A DOP2009000145A DO P2009000145 A DOP2009000145 A DO P2009000145A DO 2009000145 A DO2009000145 A DO 2009000145A DO 2009000145 A DO2009000145 A DO 2009000145A DO P2009000145 A DOP2009000145 A DO P2009000145A
Authority
DO
Dominican Republic
Prior art keywords
etinylxantine
selective
derivatives
receiver antagonists
antagonists
Prior art date
Application number
DO2009000145A
Other languages
Spanish (es)
Inventor
Christa Mueller
Joerg Hockemeyer
Nikolay Tzvetkov
Joachim Burbiel
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41294864&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2009000145(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP06026739A external-priority patent/EP1939197A1/en
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of DOP2009000145A publication Critical patent/DOP2009000145A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se revelan compuestos novedosos de la fórmula general (la) y sus sales, isómeros, diatereómeros o enantiómerosa de los mismos farmacéuticamente aceptables (la) y su uso como medicamentos, por ejemplo, en el tratamiento de trastornos del movimiento relacionados con dopamina.Novel compounds of the general formula (la) and their pharmaceutically acceptable salts, isomers, diatereomers or enantiomers thereof and their use as medicaments are disclosed, for example, in the treatment of dopamine-related movement disorders.

DO2009000145A 2006-12-22 2009-06-17 DERIVATIVES OF 8-ETINYLXANTINE AS SELECTIVE A2A RECEIVER ANTAGONISTS DOP2009000145A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06026739A EP1939197A1 (en) 2006-12-22 2006-12-22 8-ethinylxanthine derivatives as selective A2A receptor antagonists
US94524807P 2007-06-20 2007-06-20

Publications (1)

Publication Number Publication Date
DOP2009000145A true DOP2009000145A (en) 2009-07-15

Family

ID=41294864

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2009000145A DOP2009000145A (en) 2006-12-22 2009-06-17 DERIVATIVES OF 8-ETINYLXANTINE AS SELECTIVE A2A RECEIVER ANTAGONISTS

Country Status (7)

Country Link
JP (1) JP2010513353A (en)
KR (1) KR20090094465A (en)
CL (1) CL2007003778A1 (en)
DO (1) DOP2009000145A (en)
MX (1) MX2009006346A (en)
PE (1) PE20081543A1 (en)
TW (1) TW200848421A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9593118B2 (en) * 2015-04-08 2017-03-14 Lewis And Clark Pharmaceuticals, Inc. Xanthine-substituted alkynyl carbamates/reverse carbamates as A2B antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69130869T2 (en) * 1990-10-18 1999-06-10 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo XANTINE DERIVATIVES
CA2093403C (en) * 1992-04-08 1999-08-10 Fumio Suzuki Therapeutic agent for parkinson's disease
JP2613355B2 (en) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 Parkinson's disease treatment
WO1994025462A1 (en) * 1993-05-03 1994-11-10 The United States Of America, Represented By The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
CA2161011A1 (en) * 1994-02-23 1995-08-31 Fumio Suzuki Xanthine derivatives

Also Published As

Publication number Publication date
PE20081543A1 (en) 2009-01-04
JP2010513353A (en) 2010-04-30
MX2009006346A (en) 2010-03-03
KR20090094465A (en) 2009-09-07
CL2007003778A1 (en) 2009-03-27
TW200848421A (en) 2008-12-16

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