DOP2014000030A - Procedimientos para la fabricación de medicamentos útiles para el tratamiento de infecciones virales - Google Patents

Procedimientos para la fabricación de medicamentos útiles para el tratamiento de infecciones virales

Info

Publication number
DOP2014000030A
DOP2014000030A DO2014000030A DO2014000030A DOP2014000030A DO P2014000030 A DOP2014000030 A DO P2014000030A DO 2014000030 A DO2014000030 A DO 2014000030A DO 2014000030 A DO2014000030 A DO 2014000030A DO P2014000030 A DOP2014000030 A DO P2014000030A
Authority
DO
Dominican Republic
Prior art keywords
manufacture
treatment
procedures
viral infections
useful drugs
Prior art date
Application number
DO2014000030A
Other languages
English (en)
Inventor
Jill Walker
Christian Voitenleitner
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47715500&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2014000030(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of DOP2014000030A publication Critical patent/DOP2014000030A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención proporciona un procedimiento para la fabricación de medicamentos útiles para el tratamiento de Hepatitis C en un ser humano que lo necesite, el cual comprende un compuesto de las fórmulas (II) o (IIB) descrito en la presente, o una sal farmacéuticamente aceptable del mismo, en combinación con uno o más agentes terapéuticos alternativos para Hepatitis C.
DO2014000030A 2011-08-17 2014-02-17 Procedimientos para la fabricación de medicamentos útiles para el tratamiento de infecciones virales DOP2014000030A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161524429P 2011-08-17 2011-08-17
US201161526787P 2011-08-24 2011-08-24

Publications (1)

Publication Number Publication Date
DOP2014000030A true DOP2014000030A (es) 2014-06-30

Family

ID=47715500

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2014000030A DOP2014000030A (es) 2011-08-17 2014-02-17 Procedimientos para la fabricación de medicamentos útiles para el tratamiento de infecciones virales

Country Status (22)

Country Link
US (2) US9119868B2 (es)
EP (1) EP2744342B1 (es)
JP (2) JP6121419B2 (es)
KR (2) KR20140093209A (es)
CN (2) CN103929965B (es)
AU (1) AU2012296446B2 (es)
BR (1) BR112014003556A2 (es)
CA (1) CA2843502C (es)
CL (2) CL2014000394A1 (es)
CO (1) CO6880064A2 (es)
CR (1) CR20140075A (es)
DO (1) DOP2014000030A (es)
EA (2) EA201690327A1 (es)
ES (1) ES2735542T3 (es)
IL (1) IL230484A (es)
MA (1) MA35347B1 (es)
MX (1) MX2014001833A (es)
PE (1) PE20141391A1 (es)
PH (1) PH12014500381A1 (es)
SG (1) SG10201606646RA (es)
WO (1) WO2013025992A1 (es)
ZA (2) ZA201400435B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2014001833A (es) * 2011-08-17 2014-02-27 Glaxosmithkline Llc Metodos terapeuticos.
PH12014500385A1 (en) 2011-08-19 2020-06-22 Glaxo Group Ltd Benzofuran compounds for the treatment of hepatitis c virus infections
SG11201703645XA (en) * 2014-11-10 2017-06-29 Glaxosmithkline Intellectual Property (No 2) Ltd Long acting pharmaceutical compositions for hepatitis c
KR20170081257A (ko) * 2014-11-10 2017-07-11 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 C형 간염에 대한 조합 장기 작용 조성물 및 방법
CN105732602B (zh) * 2015-09-23 2017-04-19 常州寅盛药业有限公司 作为ns4b抑制剂的苯并呋喃类似物
EP3600333A4 (en) 2017-03-21 2020-11-25 The Scripps Research Institute CU AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS
EP4049680A4 (en) * 2019-10-25 2024-01-10 Sumitomo Pharma Co., Ltd. NEW SUBSTITUTED CONDENSED RING CONNECTION

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5920400A (en) * 1999-07-07 2001-01-22 Du Pont Pharmaceuticals Company Cell-based assay systems for examining hcv ns3 protease activity
EA009943B1 (ru) * 2002-11-01 2008-04-28 Вирофарма Инкорпорейтед Соединения бензофурана, композиции и способы лечения и профилактики инфекций, вызванных вирусом гепатита с, и связанных с ним заболеваний
WO2005051318A2 (en) 2003-11-24 2005-06-09 Viropharma Incorporated Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
EP2015757A4 (en) 2006-05-02 2011-01-26 Anacor Pharmaceuticals Inc HYDROLYSERESISTENT, BOROYED THERAPEUTIC USES
CA2695989A1 (en) 2007-08-10 2009-02-19 Glaxosmithkline Llc Certain nitrogen containing bicyclic chemical entities for treating viral infections
GB0719366D0 (en) * 2007-10-03 2007-11-14 Smithkline Beecham Corp Compounds
ATE539070T1 (de) * 2008-02-14 2012-01-15 Hoffmann La Roche Heterozyklische antivirale verbindungen
WO2009137500A1 (en) * 2008-05-05 2009-11-12 Wyeth 6-substituted benzofuran compounds to treat infection with hepatitis c virus
WO2011050284A1 (en) * 2009-10-23 2011-04-28 Glaxosmithkline Llc Pyrazolylpyridine antiviral agents
WO2011103063A1 (en) * 2010-02-19 2011-08-25 Glaxo Group Limited Therapeutic compounds
AU2011329485A1 (en) 2010-11-18 2013-04-18 Glaxo Group Limited Compounds
MX2014001833A (es) * 2011-08-17 2014-02-27 Glaxosmithkline Llc Metodos terapeuticos.
WO2013025975A1 (en) * 2011-08-17 2013-02-21 Glaxosmithkline Llc Combination treatments for hepatitis c
PH12014500385A1 (en) * 2011-08-19 2020-06-22 Glaxo Group Ltd Benzofuran compounds for the treatment of hepatitis c virus infections
WO2013028953A1 (en) * 2011-08-24 2013-02-28 Glaxosmithkline Llc Combination treatments for hepatitis c

Also Published As

Publication number Publication date
JP2017165732A (ja) 2017-09-21
MX2014001833A (es) 2014-02-27
CL2016000300A1 (es) 2016-09-02
US10238678B2 (en) 2019-03-26
KR101975233B1 (ko) 2019-05-07
CO6880064A2 (es) 2014-02-28
IL230484A0 (en) 2014-03-31
CA2843502A1 (en) 2013-02-21
CL2014000394A1 (es) 2014-08-01
CA2843502C (en) 2019-01-15
EA201490199A1 (ru) 2015-01-30
EP2744342B1 (en) 2019-04-24
ES2735542T3 (es) 2019-12-19
EA024357B1 (ru) 2016-09-30
CN103929965B (zh) 2016-08-17
EP2744342A4 (en) 2015-01-28
JP6121419B2 (ja) 2017-04-26
EA201690327A1 (ru) 2016-06-30
AU2012296446A1 (en) 2014-02-13
CR20140075A (es) 2014-03-24
ZA201502595B (en) 2017-01-25
NZ619985A (en) 2016-06-24
EP2744342A1 (en) 2014-06-25
CN106109479A (zh) 2016-11-16
PE20141391A1 (es) 2014-10-29
US20140212384A1 (en) 2014-07-31
US20150320777A1 (en) 2015-11-12
ZA201400435B (en) 2015-09-30
KR20140093209A (ko) 2014-07-25
IL230484A (en) 2016-11-30
SG10201606646RA (en) 2016-09-29
JP2014524446A (ja) 2014-09-22
WO2013025992A1 (en) 2013-02-21
US9119868B2 (en) 2015-09-01
BR112014003556A2 (pt) 2017-03-21
MA35347B1 (fr) 2014-08-01
EA201490199A8 (ru) 2015-12-30
PH12014500381A1 (en) 2021-07-12
AU2012296446B2 (en) 2015-07-09
CN103929965A (zh) 2014-07-16
KR20180129973A (ko) 2018-12-05

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