EA031899B9 - Производные 1,3-дифенилпропана, их получение и применение - Google Patents

Производные 1,3-дифенилпропана, их получение и применение

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Publication number
EA031899B9
EA031899B9 EA201400761A EA201400761A EA031899B9 EA 031899 B9 EA031899 B9 EA 031899B9 EA 201400761 A EA201400761 A EA 201400761A EA 201400761 A EA201400761 A EA 201400761A EA 031899 B9 EA031899 B9 EA 031899B9
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EA
Eurasian Patent Office
Prior art keywords
disease
present
preparation
diphenylpropane derivatives
metabolic
Prior art date
Application number
EA201400761A
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English (en)
Other versions
EA201400761A1 (ru
EA031899B1 (ru
Inventor
Матьё Дюберне
Жан-Франсуа Дельомель
Карин Бертран
Original Assignee
Жанфит
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Publication date
Application filed by Жанфит filed Critical Жанфит
Publication of EA201400761A1 publication Critical patent/EA201400761A1/ru
Publication of EA031899B1 publication Critical patent/EA031899B1/ru
Publication of EA031899B9 publication Critical patent/EA031899B9/ru

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Abstract

Изобретение имеет отношение к новым производным 1,3-дифенилпропана, фармацевтическим композициям, содержащим эти производные, и их терапевтическому применению, в частности, в области здоровья людей и животных. Соединения в соответствии с изобретением обладают характерными свойствами PPAR агониста. Поэтому они представляют особый интерес при лечении метаболических и/или воспалительных заболеваний и, в частности периферических и связанных с центральной нервной системой болезней, связанных с метаболическим синдромом, таких как различные формы стеатогепатита, диабета 2 типа, различные нейродегенеративные нарушения, болезнь Альцгеймера, болезнь Паркинсона и рассеянный склероз.
EA201400761A 2011-12-28 2012-12-28 Производные 1,3-дифенилпропана, их получение и применение EA031899B9 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11306790 2011-12-28
PCT/EP2012/077026 WO2013098374A1 (en) 2011-12-28 2012-12-28 1,3-diphenylpropane derivatives, preparations and uses thereof

Publications (3)

Publication Number Publication Date
EA201400761A1 EA201400761A1 (ru) 2015-05-29
EA031899B1 EA031899B1 (ru) 2019-03-29
EA031899B9 true EA031899B9 (ru) 2019-08-30

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EA201400761A EA031899B9 (ru) 2011-12-28 2012-12-28 Производные 1,3-дифенилпропана, их получение и применение

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US (1) US9115073B2 (ru)
EP (1) EP2811992A1 (ru)
JP (1) JP6140729B2 (ru)
KR (1) KR102023667B1 (ru)
CN (1) CN104185471B (ru)
AU (1) AU2012360796B2 (ru)
BR (1) BR112014016129B1 (ru)
CA (1) CA2858285C (ru)
EA (1) EA031899B9 (ru)
HK (1) HK1203061A1 (ru)
IL (1) IL233172A (ru)
IN (1) IN2014DN05789A (ru)
MX (1) MX362862B (ru)
PH (1) PH12014501443B1 (ru)
SG (1) SG11201403107TA (ru)
WO (1) WO2013098374A1 (ru)
ZA (1) ZA201405459B (ru)

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KR101761767B1 (ko) 2015-03-04 2017-07-26 한국과학기술연구원 찰콘 유도체를 포함하는 신독성 감소용 조성물
FR3050112B1 (fr) 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
WO2020208205A1 (en) 2019-04-10 2020-10-15 Genfit Combination therapy comprising compounds of formula (i) and glp-1 receptor agonists
KR20240018778A (ko) * 2022-08-03 2024-02-14 포항공과대학교 산학협력단 신규 ppar 활성 조절물질을 유효성분으로 포함하는 퇴행성 뇌질환의 예방, 개선 또는 치료용 조성물
CN120392721A (zh) * 2024-01-30 2025-08-01 哈尔滨三联药业股份有限公司 PPARα/δ双重激动剂在治疗多囊肾疾病中的应用

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FR2841900B1 (fr) 2002-07-08 2007-03-02 Genfit S A Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
BRPI0506718A (pt) * 2004-01-08 2007-05-02 Genfit compostos, processo de preparação dos mesmos, e, composição farmacêutica ou cosmética
FR2902789A1 (fr) 2006-06-21 2007-12-28 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations
FR2910892A1 (fr) * 2006-12-29 2008-07-04 Genfit Sa Derives de 1,3-diphenylpropane substitues, preparations et utilisations.

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KR20140131507A (ko) 2014-11-13
NZ626718A (en) 2016-01-29
EA201400761A1 (ru) 2015-05-29
PH12014501443A1 (en) 2014-10-08
MX2014007956A (es) 2014-08-21
CA2858285A1 (en) 2013-07-04
CN104185471A (zh) 2014-12-03
JP6140729B2 (ja) 2017-05-31
BR112014016129B1 (pt) 2022-04-05
IL233172A (en) 2016-06-30
EA031899B1 (ru) 2019-03-29
HK1203061A1 (en) 2015-10-16
BR112014016129A8 (pt) 2021-04-27
KR102023667B1 (ko) 2019-09-23
PH12014501443B1 (en) 2014-10-08
MX362862B (es) 2019-02-20
IN2014DN05789A (ru) 2015-05-15
ZA201405459B (en) 2016-07-27
US20140350112A1 (en) 2014-11-27
US9115073B2 (en) 2015-08-25
SG11201403107TA (en) 2014-09-26
CA2858285C (en) 2021-06-08
AU2012360796B2 (en) 2017-02-02
IL233172A0 (en) 2014-07-31
CN104185471B (zh) 2018-03-30
WO2013098374A1 (en) 2013-07-04
AU2012360796A1 (en) 2014-07-24
EP2811992A1 (en) 2014-12-17
BR112014016129A2 (pt) 2017-06-13
JP2015507627A (ja) 2015-03-12

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