EA200901221A1 - Композиция, содержащая рутин и полиненасыщенную жирную кислоту, имеющая ингибирующую активность в отношении 5 альфа-редуктазы - Google Patents

Композиция, содержащая рутин и полиненасыщенную жирную кислоту, имеющая ингибирующую активность в отношении 5 альфа-редуктазы

Info

Publication number
EA200901221A1
EA200901221A1 EA200901221A EA200901221A EA200901221A1 EA 200901221 A1 EA200901221 A1 EA 200901221A1 EA 200901221 A EA200901221 A EA 200901221A EA 200901221 A EA200901221 A EA 200901221A EA 200901221 A1 EA200901221 A1 EA 200901221A1
Authority
EA
Eurasian Patent Office
Prior art keywords
respect
polinatinated
fatty acid
composition containing
inhibiting activity
Prior art date
Application number
EA200901221A
Other languages
English (en)
Other versions
EA015819B1 (ru
Inventor
Джаммария Джулиани
Анна Бенедуси
Серджио Барони
Original Assignee
ДЖУЛИАНИ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДЖУЛИАНИ С.п.А. filed Critical ДЖУЛИАНИ С.п.А.
Publication of EA200901221A1 publication Critical patent/EA200901221A1/ru
Publication of EA015819B1 publication Critical patent/EA015819B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Настоящее изобретение относится к применению выбранных действующих начал природного происхождения взамен экстракта из Boehmeria nipononivea для регуляции трофики волосяных фолликулов и образования секрета сальных желез в коже и их применению при алопеции со значительными практическими преимуществами и в отношении профиля безопасности. Композиция по изобретению основана на ассоциации омега-6 полиненасыщенных кислот и рутина в фармацевтически приемлемом носителе.
EA200901221A 2007-03-21 2008-03-18 КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ РУТИН И ПОЛИНЕНАСЫЩЕННУЮ ЖИРНУЮ КИСЛОТУ, ИМЕЮЩАЯ ИНГИБИРУЮЩУЮ АКТИВНОСТЬ В ОТНОШЕНИИ 5α-РЕДУКТАЗЫ EA015819B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000555A ITMI20070555A1 (it) 2007-03-21 2007-03-21 Composizione provvista di attivita' di inibizione sulla 5 alfa-reduttasi
PCT/IB2008/000772 WO2008114141A2 (en) 2007-03-21 2008-03-18 Composition comprising rutin and polyunsaturated fatty acid having an inhibitory activity on 5 alpha-reductase

Publications (2)

Publication Number Publication Date
EA200901221A1 true EA200901221A1 (ru) 2010-04-30
EA015819B1 EA015819B1 (ru) 2011-12-30

Family

ID=39766557

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200901221A EA015819B1 (ru) 2007-03-21 2008-03-18 КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ РУТИН И ПОЛИНЕНАСЫЩЕННУЮ ЖИРНУЮ КИСЛОТУ, ИМЕЮЩАЯ ИНГИБИРУЮЩУЮ АКТИВНОСТЬ В ОТНОШЕНИИ 5α-РЕДУКТАЗЫ

Country Status (9)

Country Link
US (1) US9144560B2 (ru)
EP (1) EP2124922B1 (ru)
EA (1) EA015819B1 (ru)
ES (1) ES2424323T3 (ru)
IT (1) ITMI20070555A1 (ru)
PL (1) PL2124922T3 (ru)
PT (1) PT2124922E (ru)
UA (1) UA98638C2 (ru)
WO (1) WO2008114141A2 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8729033B2 (en) * 2008-11-03 2014-05-20 Giuliani S.P.A. Therapeutic, dietary or cosmetic use of compounds with specific anti-apoptotic activity toward caspase-3, and compositions containing these compounds
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
IT1395122B1 (it) * 2009-07-29 2012-09-05 Giuliani Spa Composizione per uso farmaceutico o cosmetico o dietetico atta a svolgere un effetto di pigmentazione dei capelli
ITMI20091940A1 (it) * 2009-11-05 2011-05-06 Functional Point S R L Composizione comprendente resveratrolo e almeno un polifenolo del vino rosso e suoi usi.
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
DE102011086636A1 (de) * 2011-11-18 2013-05-23 Henkel Ag & Co. Kgaa Haarpflegemittel mit Aminosäuren und kationischen Silikonen
DE102011086635A1 (de) * 2011-11-18 2013-05-23 Henkel Ag & Co. Kgaa Haarpflegemittel mit Antischuppenmitteln und kationischen Silikonen
US20130267598A1 (en) * 2012-02-23 2013-10-10 Dignity Sciences Limited Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same
BR112016012151B1 (pt) 2013-12-03 2020-03-10 Colgate-Palmolive Company Composição dentifrícia e uso
MX375328B (es) 2014-06-04 2025-03-06 Ds Biopharma Ltd Composiciones farmacéuticas que comprenden ácido dihomo-gamma-linolénico (dgla) y uso de las mismas
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
EP0093516B1 (en) * 1982-04-29 1986-10-01 Efamol Limited Pharmaceutical composition
US6150405A (en) * 1985-07-18 2000-11-21 Proctor; Peter H. Hair loss treatment with ascorbates
GB9419715D0 (en) 1994-09-30 1994-11-16 Boots Co Plc Hair stimulant composition
WO1997017953A1 (en) * 1995-11-13 1997-05-22 Arcturus Pharmaceutical Corporation Method for the treatment, prevention or minimization of hair loss using a source of fatty acids
WO1999022728A1 (en) * 1997-10-31 1999-05-14 Arch Development Corporation Methods and compositions for regulation of 5-alpha reductase activity
US20030224071A1 (en) * 1999-08-20 2003-12-04 Howard Murad Pharmaceutical compositions and methods for managing connective tissue ailments
FR2829692B1 (fr) 2001-09-17 2004-10-15 Lehning Lab Composition selective de six categories de substances preservant l'equilibre physiologique chez l'homme comprenant un complexe de micronutriments,un complexe d'antioxydants et un complexe d'acides gras.
WO2004078189A1 (de) * 2003-03-03 2004-09-16 Bioplanta Arzneimittel Gmbh Verwendung von rutin und isorhamnetin zur behandlung von depressiven verstimmungen und erkrankungen sowei bei anderen affektiven störungen
US7452527B2 (en) * 2003-03-28 2008-11-18 Murad, Inc. Methods of promoting hair growth
KR100499564B1 (ko) 2003-03-28 2005-07-07 신석봉 모발의 재생방법 및 발모제 조성물
FR2865635B1 (fr) 2004-01-29 2007-10-12 Oreal Procede de preparation d'une composition de traitement cosmetique a partir de fluide sous pression, et d'actifs cosmetiques non colorants sensibles a un stimulus exterieur
GB0411166D0 (en) 2004-05-19 2004-06-23 Bionovate Ltd Treatment for asthma and arthritis

Also Published As

Publication number Publication date
EP2124922B1 (en) 2013-05-15
UA98638C2 (ru) 2012-06-11
ES2424323T3 (es) 2013-10-01
WO2008114141A3 (en) 2008-12-04
US20100034904A1 (en) 2010-02-11
PT2124922E (pt) 2013-08-26
PL2124922T3 (pl) 2013-10-31
EP2124922A2 (en) 2009-12-02
EA015819B1 (ru) 2011-12-30
WO2008114141A2 (en) 2008-09-25
US9144560B2 (en) 2015-09-29
ITMI20070555A1 (it) 2007-06-20

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU