EA201190309A1 - ЛИПОПОЛИСАХАРИД Ochrobactrum intermedium И ЕГО ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИММУНОСТИМУЛЯТОРА У МЛЕКОПИТАЮЩИХ - Google Patents

ЛИПОПОЛИСАХАРИД Ochrobactrum intermedium И ЕГО ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИММУНОСТИМУЛЯТОРА У МЛЕКОПИТАЮЩИХ

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Publication number
EA201190309A1
EA201190309A1 EA201190309A EA201190309A EA201190309A1 EA 201190309 A1 EA201190309 A1 EA 201190309A1 EA 201190309 A EA201190309 A EA 201190309A EA 201190309 A EA201190309 A EA 201190309A EA 201190309 A1 EA201190309 A1 EA 201190309A1
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EA
Eurasian Patent Office
Prior art keywords
lipopolysaharid
immunity
mammal
application
ochrobactrum intermedium
Prior art date
Application number
EA201190309A
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English (en)
Other versions
EA025766B1 (ru
Inventor
Хуан Игнасио Овехеро Гисасола
Мануэль Фресно Эскудеро
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Лабораториос Овехеро, С.А.
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Application filed by Лабораториос Овехеро, С.А. filed Critical Лабораториос Овехеро, С.А.
Publication of EA201190309A1 publication Critical patent/EA201190309A1/ru
Publication of EA025766B1 publication Critical patent/EA025766B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к выделению, очистке и характеристике липополисахарида (ЛПС) штамма Ochrobactrum intermedium LMG3306 и его применению в качестве иммуностимулятора у млекопитающих, способу получения фармацевтического соединения для лечения и/или предупреждения сепсиса и в качестве адъюванта вакцины для иммуносупрессированных животных от Leishmania.
EA201190309A 2009-06-04 2009-12-31 Липополисахарид ochrobactrum intermedium и его применение в качестве иммуностимулятора у млекопитающих EA025766B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200930265A ES2352780B2 (es) 2009-06-04 2009-06-04 Lipopolisacárido de ochrobactrum intermedium contra la sepsis.
PCT/EP2009/009342 WO2010139352A1 (en) 2009-06-04 2009-12-31 Lipopolysaccharide of ochrobactrum intermedium and their use as immunostimulant of mammalians

Publications (2)

Publication Number Publication Date
EA201190309A1 true EA201190309A1 (ru) 2012-05-30
EA025766B1 EA025766B1 (ru) 2017-01-30

Family

ID=41796455

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201190309A EA025766B1 (ru) 2009-06-04 2009-12-31 Липополисахарид ochrobactrum intermedium и его применение в качестве иммуностимулятора у млекопитающих

Country Status (20)

Country Link
US (1) US9241954B2 (ru)
EP (1) EP2437754B1 (ru)
JP (1) JP5730862B2 (ru)
KR (1) KR20120061045A (ru)
CN (1) CN102802639A (ru)
AU (1) AU2009347459A1 (ru)
BR (1) BRPI0924393A2 (ru)
CA (1) CA2763266A1 (ru)
CL (1) CL2011003033A1 (ru)
CO (1) CO6470857A2 (ru)
CU (1) CU24041B1 (ru)
EA (1) EA025766B1 (ru)
ES (2) ES2352780B2 (ru)
IL (1) IL216560A0 (ru)
MX (1) MX2011012934A (ru)
NZ (1) NZ596599A (ru)
PL (1) PL2437754T3 (ru)
SG (1) SG176660A1 (ru)
WO (1) WO2010139352A1 (ru)
ZA (1) ZA201200021B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103937722B (zh) * 2014-04-24 2016-10-26 烟台地元生物科技有限公司 中间苍白杆菌及微生物菌剂和它们的应用
CN106754562B (zh) * 2017-02-14 2020-06-02 南京中医药大学 一种高产细菌多糖的菌株及其发酵中药废弃物制备多糖的方法
CN106755186B (zh) * 2017-02-14 2020-03-31 南京中医药大学 一种中间苍白杆菌胞外多糖及其在土壤改良方面的应用
CN109182159B (zh) * 2018-07-27 2021-04-23 华南农业大学 一种n-酰基高丝氨酸内酯淬灭菌及其在病害防控中的应用
EP3962493A2 (en) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V, Inc. Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
CN111053789A (zh) * 2019-11-26 2020-04-24 湖南营养树生物科技有限公司 调节免疫系统的方法和组合物
RU2736933C1 (ru) * 2020-05-20 2020-11-23 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени Г.П. Сомова" (НИИ эпидемиологии и микробиологии имени Г.П. Сомова) Адъювант
CN111909874B (zh) * 2020-08-17 2022-08-19 东北农业大学 一株生防菌i-5及其在防治紫花苜蓿根腐病中的应用
CN112625943B (zh) * 2020-12-02 2021-11-16 安徽农业大学 一种玉米用溶钾菌剂及其制备方法和应用
CA3208643A1 (en) 2021-01-18 2022-07-21 Conserv Bioscience Limited Coronavirus immunogenic compositions, methods and uses thereof
WO2024159198A2 (en) * 2023-01-27 2024-08-02 Nagy Aurangzeb Nafees Compositions and methods using tetrahydrocannabinol and compositions including same for treating indications involving inflammation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824310A (en) * 1991-10-22 1998-10-20 The United States Of America As Represented By The Department Of Health And Human Services Lipopplysaccharide conjugate vaccines
GB9706930D0 (en) 1997-04-04 1997-05-21 Univ Glasgow Leishmania vaccine
DE60131430T2 (de) 2000-01-14 2008-10-16 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
EP2170372A1 (en) * 2007-07-13 2010-04-07 Infectious Disease Research Institute Leishmania sterol 24-c-methyltransferase compositions for the prevention, treatment and diagnosis of leishmaniasis

Also Published As

Publication number Publication date
PL2437754T3 (pl) 2018-03-30
KR20120061045A (ko) 2012-06-12
JP5730862B2 (ja) 2015-06-10
CL2011003033A1 (es) 2012-07-06
WO2010139352A1 (en) 2010-12-09
CO6470857A2 (es) 2012-06-29
ZA201200021B (en) 2013-03-27
CU20110223A7 (es) 2012-06-21
EP2437754B1 (en) 2017-09-20
IL216560A0 (en) 2012-02-29
US9241954B2 (en) 2016-01-26
ES2352780B2 (es) 2011-09-15
JP2012528805A (ja) 2012-11-15
MX2011012934A (es) 2012-04-30
CN102802639A (zh) 2012-11-28
EP2437754A1 (en) 2012-04-11
CU24041B1 (es) 2014-11-27
EA025766B1 (ru) 2017-01-30
ES2653202T3 (es) 2018-02-06
BRPI0924393A2 (pt) 2016-09-06
NZ596599A (en) 2013-08-30
SG176660A1 (en) 2012-01-30
ES2352780A1 (es) 2011-02-23
AU2009347459A1 (en) 2011-12-22
CA2763266A1 (en) 2010-12-09
US20120107352A1 (en) 2012-05-03

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