EA201201480A1 - Адгезионные ретардированные составы для местного применения куркумина - Google Patents
Адгезионные ретардированные составы для местного применения куркуминаInfo
- Publication number
- EA201201480A1 EA201201480A1 EA201201480A EA201201480A EA201201480A1 EA 201201480 A1 EA201201480 A1 EA 201201480A1 EA 201201480 A EA201201480 A EA 201201480A EA 201201480 A EA201201480 A EA 201201480A EA 201201480 A1 EA201201480 A1 EA 201201480A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- curkumin
- adhesive
- local application
- retarded compositions
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000853 adhesive Substances 0.000 title 1
- 230000001070 adhesive effect Effects 0.000 title 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 2
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229940109262 curcumin Drugs 0.000 abstract 1
- 235000012754 curcumin Nutrition 0.000 abstract 1
- 239000004148 curcumin Substances 0.000 abstract 1
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003232 mucoadhesive effect Effects 0.000 abstract 1
- 239000004584 polyacrylic acid Substances 0.000 abstract 1
- 230000000979 retarding effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение относится к медицине и предназначено для изготовления куркуминовых составов путем совместного использования растворителей с полиакриловой кислотой, которые устойчивы в жидкой форме, проявляют как мукоадгезивные, так и ретардирующие свойства и обеспечивают растворимость действующего вещества до 15% (мас./об.).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0073710A AT509777B1 (de) | 2010-04-30 | 2010-04-30 | Adhesive retardformulierungen zur lokalen verabreichung von curcumin |
| PCT/EP2011/056836 WO2011135073A1 (de) | 2010-04-30 | 2011-04-29 | Adhesive retardformulierungen zur lokalen verabreichung von curcumin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201201480A1 true EA201201480A1 (ru) | 2013-03-29 |
Family
ID=44201889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201201480A EA201201480A1 (ru) | 2010-04-30 | 2011-04-29 | Адгезионные ретардированные составы для местного применения куркумина |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130052145A1 (ru) |
| EP (1) | EP2563351A1 (ru) |
| JP (1) | JP2013525412A (ru) |
| AT (1) | AT509777B1 (ru) |
| AU (1) | AU2011247569A1 (ru) |
| CA (1) | CA2797779A1 (ru) |
| EA (1) | EA201201480A1 (ru) |
| IL (1) | IL222616A0 (ru) |
| MX (1) | MX2012012476A (ru) |
| WO (1) | WO2011135073A1 (ru) |
| ZA (1) | ZA201209038B (ru) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201504187YA (en) | 2010-05-28 | 2015-06-29 | Solazyme Inc | Tailored oils produced from recombinant heterotrophic microorganisms |
| EP3213760A4 (en) * | 2014-10-27 | 2018-06-20 | FBM Indústria Farmacêutica Ltda. | Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and method for producing same; base pharmaceutical composition for preparing the pharmaceutical compositions and method for producing same |
| JP2016150930A (ja) * | 2015-02-19 | 2016-08-22 | 花王株式会社 | ディフェンシン発現促進剤 |
| AU2021373070B2 (en) | 2020-11-09 | 2023-08-24 | Albert Einstein College Of Medicine | Transdermal delivery formulations |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8283135B2 (en) * | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| US20060172007A1 (en) * | 2001-05-01 | 2006-08-03 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
| US20070003582A1 (en) * | 2003-11-25 | 2007-01-04 | Heng Madalene C | Medicine for the treatment of acne and for reversing the signs of age and sun damage and method for using same |
| US20050244522A1 (en) * | 2004-04-30 | 2005-11-03 | Carrara Dario Norberto R | Permeation enhancer comprising genus Curcuma or germacrone for transdermal and topical administration of active agents |
| DE102004043945A1 (de) * | 2004-09-11 | 2006-03-30 | Henkel Kgaa | Mund-, Zahn- und Zahnprotesenpflegemittel enthaltend die Plaquebildung inhibierende Substanzen |
| BRPI0713574A2 (pt) * | 2006-06-30 | 2012-10-23 | Piramal Life Sciences Ltd | composições herbais para o tratamento de doenças da cavidade oral |
| ITMI20071136A1 (it) * | 2007-06-04 | 2008-12-05 | Velleja Res Srl | Formulazioni topiche per la prevenzione e il trattamento degli stati infiammatori e/o infettivi dell'aera genitale |
| DE102007049612A1 (de) * | 2007-10-17 | 2009-06-10 | Evonik Goldschmidt Gmbh | Bioaktive Zusammensetzung für kosmetische Anwendungen |
| TW201019949A (en) * | 2008-10-16 | 2010-06-01 | Herbalscience Group Llc | Extracts of curcuma and methods of use thereof |
| EP2346520B1 (en) | 2008-11-17 | 2014-11-26 | Laila Pharmaceuticals Pvt. Ltd. | Curcuminoids and its metabolites for the application in ocular diseases |
| WO2010115852A1 (en) | 2009-04-03 | 2010-10-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Curcuminoids in combination docetaxel for the treatment of cancer and tumour metastasis |
-
2010
- 2010-04-30 AT AT0073710A patent/AT509777B1/de not_active IP Right Cessation
-
2011
- 2011-04-29 AU AU2011247569A patent/AU2011247569A1/en not_active Abandoned
- 2011-04-29 EP EP11717608A patent/EP2563351A1/de not_active Withdrawn
- 2011-04-29 CA CA2797779A patent/CA2797779A1/en not_active Abandoned
- 2011-04-29 US US13/642,142 patent/US20130052145A1/en not_active Abandoned
- 2011-04-29 WO PCT/EP2011/056836 patent/WO2011135073A1/de not_active Ceased
- 2011-04-29 EA EA201201480A patent/EA201201480A1/ru unknown
- 2011-04-29 JP JP2013506676A patent/JP2013525412A/ja not_active Withdrawn
- 2011-04-29 MX MX2012012476A patent/MX2012012476A/es not_active Application Discontinuation
-
2012
- 2012-10-22 IL IL222616A patent/IL222616A0/en unknown
- 2012-11-29 ZA ZA2012/09038A patent/ZA201209038B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201209038B (en) | 2014-02-26 |
| EP2563351A1 (de) | 2013-03-06 |
| AT509777A1 (de) | 2011-11-15 |
| AU2011247569A1 (en) | 2012-11-01 |
| IL222616A0 (en) | 2012-12-31 |
| WO2011135073A1 (de) | 2011-11-03 |
| CA2797779A1 (en) | 2011-11-03 |
| MX2012012476A (es) | 2013-02-27 |
| JP2013525412A (ja) | 2013-06-20 |
| US20130052145A1 (en) | 2013-02-28 |
| AT509777B1 (de) | 2012-03-15 |
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