EA201400151A1 - Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот, способы их получения и применения - Google Patents

Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот, способы их получения и применения

Info

Publication number
EA201400151A1
EA201400151A1 EA201400151A EA201400151A EA201400151A1 EA 201400151 A1 EA201400151 A1 EA 201400151A1 EA 201400151 A EA201400151 A EA 201400151A EA 201400151 A EA201400151 A EA 201400151A EA 201400151 A1 EA201400151 A1 EA 201400151A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
microorganisms
eycopentena
acid
produce
Prior art date
Application number
EA201400151A
Other languages
English (en)
Other versions
EA034980B1 (ru
Inventor
III Джозеф У. Пфайфер
Джон Милтон Хансен
Хосе Р. Гарсиа
Сяо Дэниель Дун
Пол Уоррен Беренс
Кирк Е. Эпт
Original Assignee
ДСМ АйПй АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПй АССЕТС Б.В. filed Critical ДСМ АйПй АССЕТС Б.В.
Publication of EA201400151A1 publication Critical patent/EA201400151A1/ru
Publication of EA034980B1 publication Critical patent/EA034980B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Birds (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Изобретение направлено на изолированные микроорганизмы, а также на их штаммы и мутанты, биомассы, микробные масла, композиции и культуры; способы получения микробных масел, биомасс и мутантов; и способы применения изолированных микроорганизмов, биомасс и микробных масел.
EA201400151A 2011-07-21 2012-07-20 Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот, способы их получения и применения EA034980B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161510464P 2011-07-21 2011-07-21
PCT/US2012/047728 WO2013013208A2 (en) 2011-07-21 2012-07-20 Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

Publications (2)

Publication Number Publication Date
EA201400151A1 true EA201400151A1 (ru) 2014-10-30
EA034980B1 EA034980B1 (ru) 2020-04-14

Family

ID=47558749

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400151A EA034980B1 (ru) 2011-07-21 2012-07-20 Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот, способы их получения и применения

Country Status (20)

Country Link
US (6) US9045785B2 (ru)
EP (4) EP2734630B1 (ru)
JP (3) JP6338285B2 (ru)
KR (2) KR102158437B1 (ru)
CN (3) CN104011217B (ru)
AR (1) AR087944A1 (ru)
AU (2) AU2012285803B2 (ru)
BR (2) BR122015020130A2 (ru)
CA (1) CA2842374C (ru)
CL (2) CL2014000156A1 (ru)
DK (1) DK3050972T3 (ru)
EA (1) EA034980B1 (ru)
ES (2) ES2859752T3 (ru)
IL (1) IL230500B (ru)
MX (2) MX385408B (ru)
MY (1) MY169454A (ru)
PH (1) PH12014500169B1 (ru)
SG (1) SG10201605966TA (ru)
WO (1) WO2013013208A2 (ru)
ZA (2) ZA201400620B (ru)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3118954B2 (ja) 1992-05-14 2000-12-18 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3196326B2 (ja) 1992-06-22 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3196316B2 (ja) 1992-05-20 2001-08-06 石川島播磨重工業株式会社 ブロー成形装置
JP3125443B2 (ja) 1992-07-02 2001-01-15 石川島播磨重工業株式会社 偏平ブロー成形装置
JP3196323B2 (ja) 1992-06-09 2001-08-06 石川島播磨重工業株式会社 偏平ブロー成形機のパリソン皺矯正装置
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
MX342216B (es) 2011-07-21 2016-09-20 Dsm Ip Assets Bv Composiciones de acidos grasos.
US9587215B2 (en) 2014-08-07 2017-03-07 General Electric Company Devices, systems and methods for automated transfer of a sample
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
CN107075540A (zh) 2014-10-02 2017-08-18 赢创德固赛有限公司 用于制备具有高细胞稳定性的含pufa生物质的方法
CN106793803B (zh) * 2014-10-02 2021-03-09 赢创运营有限公司 通过挤压含pufa的生物质来制备含pufa的饲料的方法
BR112017005388B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo biomassa de aurantiochytrium
CN104962589B (zh) * 2015-08-05 2019-02-26 嘉必优生物技术（武汉）股份有限公司 一种富含磷脂型多不饱和脂肪酸的微生物油脂及制备方法
JP6998934B2 (ja) * 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 脂質含有細胞から脂質を単離する方法
KR102405390B1 (ko) 2016-07-13 2022-06-03 에보닉 오퍼레이션스 게엠베하 용해된 지질을 함유하는 바이오매스로부터 지질을 분리하는 방법
CA3034122A1 (en) 2016-08-19 2018-02-22 Noblegen Inc. Methods and uses of dissolved organic material fractions for binding metal ions
ES2872009T3 (es) 2016-12-27 2021-11-02 Evonik Degussa Gmbh Método de aislamiento de lípidos a partir de una biomasa que contiene lípidos
US11053139B2 (en) 2017-04-07 2021-07-06 Noblegen Inc. Methods and uses of encapsulated exudates and dried euglena biomass for binding metal
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
WO2019219443A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
US20210277430A1 (en) * 2020-03-09 2021-09-09 Lanzatech, Inc. Fermentation process for the production of lipids
KR102614551B1 (ko) * 2020-12-07 2023-12-15 씨제이제일제당 주식회사 단일 미세조류로부터 단백질 및 오메가-3 지방산을 포함하는 바이오매스를 제조하는 방법 및 이에 의해 제조된 바이오매스
WO2023144707A1 (en) 2022-01-25 2023-08-03 Dsm Ip Assets B.V. Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production
CN115927005B (zh) * 2022-10-14 2024-11-22 广西中医药大学 两面针内生真菌y118的固体发酵培养基及其制备和培养方法
CN116479063B (zh) * 2023-05-04 2024-02-20 厦门汇盛生物有限公司 一种ω-3多不饱和脂肪酸的生产方法
WO2025019424A1 (en) * 2023-07-14 2025-01-23 Dsm Ip Assets B.V. Microbial oils having high epa content and methods of making the same
CN118755584B (zh) * 2024-08-06 2025-04-29 杭州合碳创物科技有限公司 一种高产epa的裂殖壶菌及其应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US6451567B1 (en) * 1988-09-07 2002-09-17 Omegatech, Inc. Fermentation process for producing long chain omega-3 fatty acids with euryhaline microorganisms
EP2140863A1 (en) * 1993-06-09 2010-01-06 Martek Biosciences Corporation Use of docosahexaenoic acid for the manufacture of a medicament for the treatment of neurological disorders
WO1996033263A1 (en) 1995-04-17 1996-10-24 JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
US6255505B1 (en) * 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
AU748220C (en) 1997-08-01 2003-02-27 Martek Biosciences Corporation DHA-containing nutritional compositions and methods for their production
KR101591834B1 (ko) 2000-01-19 2016-02-18 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
EP1707055A3 (en) * 2000-01-28 2009-01-14 Martek Biosciences Corporation Enhanced production of lipids containing polyenoic fatty acids by very high density cultures of eukaryotic microbes in fermentors
US6410282B1 (en) * 2000-03-30 2002-06-25 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid fungi
DE10102337A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
US20040203120A1 (en) * 2002-03-22 2004-10-14 Council Of Scientific And Industrial Research Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
JP4280158B2 (ja) 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
US20050019880A1 (en) * 2003-03-31 2005-01-27 Council Of Scientific And Industrial Research Method of enhancing levels of polyunsaturated fatty acids in thraustochytrid protists
JP4839454B2 (ja) * 2003-12-30 2011-12-21 ディーエスエム アイピー アセッツ ビー．ブイ． 脱気方法
ES2529572T3 (es) * 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
US9023616B2 (en) * 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
CL2008002020A1 (es) * 2007-07-12 2008-11-14 Ocean Nutrition Canada Ltd Metodo de modificacion de un aceite, que comprende hidrolizar gliceridos con una solucion de lipasa thermomyces lanuginosus, separar la fraccion de acido graso saturado de la fraccion de glicerido hidrolizado y esterificar los gliceridos hidrolizados en la presencia de candida antarctica lipasa b; y composicion de aceite.
KR101650584B1 (ko) * 2007-08-31 2016-08-23 디에스엠 아이피 어셋츠 비.브이. 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산
US9695372B2 (en) * 2007-09-11 2017-07-04 Sapphire Energy, Inc. Methods of producing organic products with photosynthetic organisms
EA019387B1 (ru) * 2007-09-12 2014-03-31 Мартек Биосайнсиз Корпорейшн Способ получения биологического масла и его использование в способе получения биодизеля
US8323935B2 (en) * 2007-10-03 2012-12-04 E I Du Pont De Nemours And Company Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production
EP4183883A1 (en) * 2009-03-19 2023-05-24 DSM IP Assets B.V. Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
EP2519625B1 (en) * 2009-12-28 2018-09-26 DSM IP Assets B.V. Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof
CA2993690C (en) * 2010-01-19 2022-03-22 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
EP2561050A1 (en) * 2010-04-22 2013-02-27 E.I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
DK2580342T3 (da) * 2010-06-09 2019-07-01 Fermentalg Sammensætninger omfattende eicosapentaensyre egnet til høj oprensning
EP2734626B1 (en) * 2011-07-21 2020-12-16 DSM IP Assets B.V. Microbial oils enriched in polyunsaturated fatty acids

Also Published As

Publication number Publication date
SG10201605966TA (en) 2016-09-29
AU2016256769B2 (en) 2018-01-18
US20170245523A1 (en) 2017-08-31
ES2774778T3 (es) 2020-07-22
US20150094382A1 (en) 2015-04-02
KR20190082331A (ko) 2019-07-09
WO2013013208A2 (en) 2013-01-24
JP2020036602A (ja) 2020-03-12
BR112014001443A2 (pt) 2017-11-21
KR102038715B1 (ko) 2019-10-31
CN104011217B (zh) 2018-09-04
AR087944A1 (es) 2014-04-30
EP3050972A3 (en) 2016-11-02
IL230500B (en) 2018-04-30
BR112014001443B1 (pt) 2021-11-16
NZ620578A (en) 2015-09-25
EP2734630B1 (en) 2019-12-25
JP2017200480A (ja) 2017-11-09
AU2012285803A1 (en) 2014-02-20
MX2014000759A (es) 2014-05-07
EP3050972A2 (en) 2016-08-03
NZ712497A (en) 2016-09-30
EP4585049A2 (en) 2025-07-16
CN119899748A (zh) 2025-04-29
JP7134938B2 (ja) 2022-09-12
BR122015020130A2 (pt) 2019-08-27
ZA201400620B (en) 2015-12-23
KR20140046469A (ko) 2014-04-18
EP2734630A4 (en) 2015-07-29
EP3831952A1 (en) 2021-06-09
CN105255738B (zh) 2024-12-27
US20260165347A1 (en) 2026-06-18
MY169454A (en) 2019-04-11
CL2015001217A1 (es) 2015-06-26
EP2734630A2 (en) 2014-05-28
AU2016256769A1 (en) 2016-12-01
EA034980B1 (ru) 2020-04-14
CL2014000156A1 (es) 2014-06-13
HK1198545A1 (en) 2015-05-15
PH12014500169B1 (en) 2018-11-23
US9045785B2 (en) 2015-06-02
IL230500A0 (en) 2014-03-31
CN105255738A (zh) 2016-01-20
US20130172590A1 (en) 2013-07-04
EP3050972B1 (en) 2020-11-18
MX385408B (es) 2025-03-18
ZA201502764B (en) 2017-01-25
WO2013013208A3 (en) 2013-03-28
MX351174B (es) 2017-10-04
ES2859752T3 (es) 2021-10-04
KR102158437B1 (ko) 2020-09-22
PH12014500169A1 (en) 2014-02-24
US20150223492A1 (en) 2015-08-13
CA2842374A1 (en) 2013-01-24
CA2842374C (en) 2019-03-05
DK3050972T3 (da) 2021-02-08
AU2012285803B2 (en) 2016-08-25
US20220322705A1 (en) 2022-10-13
CN104011217A (zh) 2014-08-27
JP2014520573A (ja) 2014-08-25
JP6338285B2 (ja) 2018-06-06
NZ710646A (en) 2015-12-24

Similar Documents

Publication Publication Date Title
EA201290656A1 (ru) Микроорганизмы, продуцирующие эйкозапентаеновую кислоту, композиции жирных кислот и способы их получения и применения
EA201190218A1 (ru) Траустохитридиевые композиции жирных кислот и способы их получения и применения
MX351174B (es) Microorganismos que producen acido eicosapentaenoico, composiciones de acidos grasos,y metodos para prepararlos y usos de los mismos.
EA201201278A1 (ru) Штаммы дрожжей и их использование при производстве липидов
PH12014500588A1 (en) Microorganisms and methods for producing alkenes
MY158663A (en) Fermentation broth formulations
UY34333A (es) ?métodos y composiciones para el control de malezas, y métodos para reducir la expresión de enzima dhps?
WO2011127409A3 (en) Methods and compositions related to fatty alcohol biosynthetic enzymes
EA201270151A1 (ru) Способы и композиции для рекомбинантного биосинтеза h-алканов
EA201101626A1 (ru) Бактерии с высокоэффективным метаболизмом
WO2014093505A3 (en) Acp-mediated production of fatty acid derivatives
EA201490895A1 (ru) Производство сахарного спирта из биомассы
EA201070605A8 (ru) Применение бактерий для производства биоэнергии
DE602007005233D1 (de) Verfahren zur herstellung von l-aminosäure
MX391947B (es) Produccion microbiana de alcanolamidas y amidoaminas y usos de las mismas.
MX2017012554A (es) Microalgas adaptadas para condiciones de cultivo heterotrofo.
GB201122220D0 (en) Novel emoillients
MY174023A (en) Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
MY179079A (en) Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
MY152262A (en) Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
TH127465A (th) วิธีผลิตน้ำมันหรือไขมันที่มีลอริค แอซิด

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM