EA201592012A1 - Применение флагеллина для улучшенной химиотерапии - Google Patents

Применение флагеллина для улучшенной химиотерапии

Info

Publication number
EA201592012A1
EA201592012A1 EA201592012A EA201592012A EA201592012A1 EA 201592012 A1 EA201592012 A1 EA 201592012A1 EA 201592012 A EA201592012 A EA 201592012A EA 201592012 A EA201592012 A EA 201592012A EA 201592012 A1 EA201592012 A1 EA 201592012A1
Authority
EA
Eurasian Patent Office
Prior art keywords
flagellin
application
improved chemotherapy
chemotherapy
relates
Prior art date
Application number
EA201592012A
Other languages
English (en)
Other versions
EA201592012A8 (ru
Inventor
Андрей ГУДКОВ
Людмила Г. Бурделя
Original Assignee
Кливлэнд Биолабс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кливлэнд Биолабс, Инк. filed Critical Кливлэнд Биолабс, Инк.
Publication of EA201592012A1 publication Critical patent/EA201592012A1/ru
Publication of EA201592012A8 publication Critical patent/EA201592012A8/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к способам и композициям, которые можно применять для лечения различных заболеваний, в том числе рака. Настоящее изобретение относится, в частности, к комбинированным терапевтическим стратегиям улучшения эффективности химиотерапии.
EA201592012A 2014-02-21 2015-02-20 Применение флагеллина для улучшенной химиотерапии EA201592012A8 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461942927P 2014-02-21 2014-02-21
PCT/US2015/016850 WO2015127227A1 (en) 2014-02-21 2015-02-20 Uses of flagellin for improved chemotherapy

Publications (2)

Publication Number Publication Date
EA201592012A1 true EA201592012A1 (ru) 2017-02-28
EA201592012A8 EA201592012A8 (ru) 2018-10-31

Family

ID=53879029

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201592012A EA201592012A8 (ru) 2014-02-21 2015-02-20 Применение флагеллина для улучшенной химиотерапии

Country Status (2)

Country Link
EA (1) EA201592012A8 (ru)
WO (1) WO2015127227A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420317B (zh) * 2019-07-25 2022-11-22 中国人民解放军军事科学院军事医学研究院 Cblb502蛋白在防治创伤后应激障碍中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050206A1 (es) * 2003-05-26 2005-03-26 Schering Ag Composicion farmaceutica que contiene un inhibidor de histona deacetilasa
US8580321B2 (en) * 2003-12-02 2013-11-12 The Cleveland Clinic Foundation Method for reducing the effects of chemotherapy using flagellin related polypeptides
US20090124557A1 (en) * 2007-04-16 2009-05-14 Yeda Research And Development Co. Ltd. Compositions and methods for treating cancer

Also Published As

Publication number Publication date
EA201592012A8 (ru) 2018-10-31
WO2015127227A1 (en) 2015-08-27

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