EA202193251A1 - Пептидомиметики для лечения коронавирусной и пикорнавирусной инфекций - Google Patents

Пептидомиметики для лечения коронавирусной и пикорнавирусной инфекций

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Publication number
EA202193251A1
EA202193251A1 EA202193251A EA202193251A EA202193251A1 EA 202193251 A1 EA202193251 A1 EA 202193251A1 EA 202193251 A EA202193251 A EA 202193251A EA 202193251 A EA202193251 A EA 202193251A EA 202193251 A1 EA202193251 A1 EA 202193251A1
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EA
Eurasian Patent Office
Prior art keywords
coronavirus
sars
viruses
peptidomimetics
treatment
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Application number
EA202193251A
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English (en)
Inventor
Рэймонд Ф. Скинази
Кейван ЗАНДИ
Фрэнк Амблард
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Эмори Юниверсити
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Application filed by Эмори Юниверсити filed Critical Эмори Юниверсити
Publication of EA202193251A1 publication Critical patent/EA202193251A1/ru

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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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  • Chemical & Material Sciences (AREA)
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Abstract

Представлены соединения, композиции и способы предупреждения, лечения или излечения коронавирусной, пикорнавирусной инфекции и/или инфекции вирусом из семейства Hepeviridae у людей или других животных-хозяев. Конкретные вирусы, которые можно лечить, включают в себя энтеровирусы. В соответствии с одним вариантом осуществления соединения могут применяться для лечения вирусной инфекции, вызывающей тяжелый острый респираторный синдром, такой как человеческий коронавирус 229E, SARS, MERS, SARS-CoV-1 (OC43) и SARS-CoV-2. В соответствии с другим вариантом осуществления способы применяли для лечения пациента, одновременно инфицированного двумя или более такими вирусами или комбинацией одного или более таких вирусов и норовируса.
EA202193251A 2019-06-05 2020-06-04 Пептидомиметики для лечения коронавирусной и пикорнавирусной инфекций EA202193251A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962857674P 2019-06-05 2019-06-05
PCT/US2020/036171 WO2020247665A1 (en) 2019-06-05 2020-06-04 Peptidomimetics for the treatment of coronavirus and picornavirus infections

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EA202193251A1 true EA202193251A1 (ru) 2022-03-10

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US (2) US11207370B2 (ru)
EP (1) EP3980400B1 (ru)
KR (1) KR20220026538A (ru)
CN (1) CN114026067A (ru)
AU (1) AU2020289560A1 (ru)
BR (1) BR112021024310A2 (ru)
CA (1) CA3139977A1 (ru)
EA (1) EA202193251A1 (ru)
MX (1) MX2021014742A (ru)
WO (1) WO2020247665A1 (ru)

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