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Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
La invención se refiere a los analogos de la FLINT que son resistentes a la proteolisis in vivo e in vitro en la posición 218 de la FLINT madura, a los usos clínicos y terapéuticos de los mismos y a las formulaciones farmacéuticas que comprenden dichos análogos.The invention relates to FLINT analogs that are resistant to proteolysis in vivo and in vitro at position 218 of mature FLINT, to clinical and therapeutic uses thereof, and to pharmaceutical formulations comprising such analogs.
"PIRAZOLO [4,3, e] NOVEDOUS REPLACED DIAZEPINS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, ITS USE AS MEDICINAL PRODUCTS AND PROCESSES TO PREPARE THEM
NEW DERIVATIVES OF THERAPEUTICALLY ACTIVE PEPTIDES IN THE BLOOD COAGULATION CHAIN, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.