ECSP003473A - DERIVATIVES OF 3 (5) - AMINO - PIRAZOL, PROCESS FOR ITS PREPARATION AND USE AS ANTI-TUMOR AGENTS - Google Patents
DERIVATIVES OF 3 (5) - AMINO - PIRAZOL, PROCESS FOR ITS PREPARATION AND USE AS ANTI-TUMOR AGENTSInfo
- Publication number
- ECSP003473A ECSP003473A ECSP003473A ECSP003473A EC SP003473 A ECSP003473 A EC SP003473A EC SP003473 A ECSP003473 A EC SP003473A EC SP003473 A ECSP003473 A EC SP003473A
- Authority
- EC
- Ecuador
- Prior art keywords
- derivatives
- amino
- pirazol
- preparation
- alkyl
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- JVVRJMXHNUAPHW-UHFFFAOYSA-N 1h-pyrazol-5-amine Chemical class NC=1C=CNN=1 JVVRJMXHNUAPHW-UHFFFAOYSA-N 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- -1 cyclolakyl Chemical group 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compuestos que son derivados de 3-amino-pirazol, representados por la fórmula (I): (gráfico), en la cual: R es un grupo cicloalquilo C3-C6, opcionalmente sustituido por un grupo alquilo o arilalquilo C1-C6 de cadena recta o ramificada; R1 es un grupo alquilo C1-C6, alquenilo C2-C4, ciclolaquilo, cicloalquenilo, heterociclilo, arilo, arilalquilo, arilcarbonilo, ariloxialquilo o arilalquenilo, de cadena recta o ramificada, cada uno de los cuales puede estar opcionalmente sustituido en forma adicional, según se indica en la dsecripción; o una sal farmacéuticamente aceptable del mismo. Los compuestos resultan de utilidad para el tratamiento del cáncer, de los trastornos proliferativos de las células del mal de Alzheimer, de las infecciones virales, de las enfermedades autoinmunes o de las enfermedades neurodegenerativas.Compounds that are derivatives of 3-amino-pyrazole, represented by formula (I): (graph), in which: R is a C3-C6 cycloalkyl group, optionally substituted by a straight chain C1-C6 alkyl or arylalkyl group or branched; R1 is a C1-C6 alkyl, C2-C4 alkenyl, cyclolakyl, cycloalkenyl, heterocyclyl, aryl, arylalkyl, arylcarbonyl, aryloxyalkyl or arylalkenyl group, each of which may optionally be additionally substituted, depending on indicated in the description; or a pharmaceutically acceptable salt thereof. The compounds are useful for the treatment of cancer, proliferative disorders of Alzheimer's disease cells, viral infections, autoimmune diseases or neurodegenerative diseases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003473 ECSP003473A (en) | 2000-05-15 | 2000-05-15 | DERIVATIVES OF 3 (5) - AMINO - PIRAZOL, PROCESS FOR ITS PREPARATION AND USE AS ANTI-TUMOR AGENTS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003473 ECSP003473A (en) | 2000-05-15 | 2000-05-15 | DERIVATIVES OF 3 (5) - AMINO - PIRAZOL, PROCESS FOR ITS PREPARATION AND USE AS ANTI-TUMOR AGENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003473A true ECSP003473A (en) | 2000-08-18 |
Family
ID=42041099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003473 ECSP003473A (en) | 2000-05-15 | 2000-05-15 | DERIVATIVES OF 3 (5) - AMINO - PIRAZOL, PROCESS FOR ITS PREPARATION AND USE AS ANTI-TUMOR AGENTS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003473A (en) |
-
2000
- 2000-05-15 EC ECSP003473 patent/ECSP003473A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR026122A1 (en) | DERIVATIVES OF 3 (5) -AMINO-PIRAZOL, PROCEDURE FOR ITS PREPARATION AND ITS USE AS ANTITUMOR AGENT | |
| EA200200249A1 (en) | DERIVATIVES 3 (5) -UREIDOPYRAZOL, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION AS ANTI-TUMOR AGENTS | |
| SV2002000504A (en) | REPLACED BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH REF.PC10760 / 20205 / BB | |
| UY28132A1 (en) | PIRROLOPIRIMIDINE DERIVATIVES | |
| PY0225352A (en) | NEW PIPERAZINE DERIVATIVES | |
| UY28150A1 (en) | THERAPEUTIC AGENTS | |
| CY1113323T1 (en) | [3,4-D] DIOXOLANIUM COMPOUNDS FOR USE IN THE TREATMENT OF VIRUS INFECTIONS AND CANCER | |
| UY28578A1 (en) | AMIDA DERIVATIVES | |
| SV2005001918A (en) | METHODS TO PREPARE DERIVATIVES 7- (B-D-RIBOFURANOSIL SUBSTITUTED IN 2 ') - 4 (NR2R3) -5 (ETIN-1-ILO REPLACED) -PIRROL [2,3-D] PYRIMIDINE | |
| UY30411A1 (en) | SUBSTITUTED DERIVATIVES OF THE ACETATE OF 2,3,4, -TETRAHYDROIMIDAZO- [1,5-A] -PIRIMIDIN-6-AMINA, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS | |
| UY28526A1 (en) | GLUCOCORTICOID MIMETICS, METHODS OF PREPARATION PHARMACEUTICAL COMPOSITIONS AND USES OF THE SAME | |
| UY27333A1 (en) | NUCLEOTIDOS 4` REPLACED | |
| AR053162A1 (en) | COMPOUND 5 - OXO - REPLACED PIRROLIDIN, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND ITS USE TO PREPARE A MEDICINAL PRODUCT FOR THE TREATMENT OF GLAUCOMA. | |
| CO5031253A1 (en) | RECEIVING ANTAGONISTS Y5 OF NEUROPEPTIDES PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| AR046272A1 (en) | DIPEPTIDIL PEPTIDASA IV INHIBITORS | |
| UY32462A (en) | NEW BIFENYLL DERIVATIVES FOR HEPATITIS C 644 VIRUS INFECTION TREATMENT | |
| AR051997A1 (en) | TRICYCLIC HETEROCICLES, ITS OBTAINING AND USE OF THE SAME C OMO PHARMACEUTICAL AGENTS | |
| CR6698A (en) | CORTICOTROPINE RELEASE FACTOR ANTAGONISTS | |
| AR024060A1 (en) | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | |
| AR101177A1 (en) | SYK INHIBITORS | |
| CO4810375A1 (en) | DERIVATIVES OF 9-AMINO-3-KETO Erythromycin | |
| EA200600071A1 (en) | Derivatives of N-phenylpyrazine and Methods for the Prevention or Treatment of Diseases Associated with 5HT-Receptor | |
| ECSP056115A (en) | ANTAGONISTS OF A2A-2-ALQUINIL- AND 2-ALQUENIL-PIRAZOLO- [4,3-e] -1,2,4-TRIAZOLO- [1,5-c] -PIRIMIDINE ADENOSINE RECEPTOR | |
| UY26920A1 (en) | 7 - PYRIDOPIRIMIDIN OXY | |
| PA8568101A1 (en) | INDOLIL-UREA DERIVED FROM USEFUL TIENOPIRIDINS AS ANTIANGIOGEN AGENTS, AND PROCEDURES FOR USE |